Search Results - "Budgen, Bradley"

Inhibition of the PCR by genomic DNA by Latham, Sue, Hughes, Elizabeth, Budgen, Bradley, Morley, Alexander

“…qPCR, is widely used for quantifying minimal residual disease (MRD) and is conventionally performed according to guidelines proposed by the EuroMRD consortium…”
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Sources of error in measurement of minimal residual disease in childhood acute lymphoblastic leukemia by Latham, Sue, Hughes, Elizabeth, Budgen, Bradley, Mechinaud, Francoise, Crock, Catherine, Ekert, Henry, Campbell, Peter, Morley, Alexander

“…The level of minimal residual disease (MRD) in marrow predicts outcome and guides treatment in childhood acute lymphoblastic leukemia (ALL) but accurate…”
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Rapid isolation of translocation breakpoints in chronic myeloid and acute promyelocytic leukaemia by Bartley, Paul A., Martin‐Harris, Michael H., Budgen, Bradley J., Ross, David M., Morley, Alexander A.

“…Summary Isolation and sequencing of the translocation breakpoint in chronic myeloid leukaemia‐(CML) and acute promyelocytic leukaemia (APML) may help to…”
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Patient-Specific MRD Primers Amplify with Uniformly High Efficiency by Morley, Alexander A, Latham, Sue, Hughes, Elizabeth, Budgen, Bradley

“…The use of PCR to quantify MRD has been inhibited in North America owing to lack of insurance due to concern by the FDA that the amplification efficiency (AE)…”
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Patient-Specific Minimal Residual Disease Primers Amplify with Uniformly High Efficiency by Latham, Susan, Hughes, Elizabeth, Budgen, Bradley, Bartley, Paul, Morley, Alexander A.

“…The widespread use of PCR to quantify minimal residual disease has been hampered by the apparently wide variation in amplification efficiency (AE) of PCR…”
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Sensitive Measurement of Minimal Residual Disease in Blood by HAT-PCR by Latham, Sue, Hughes, Elizabeth, Budgen, Bradley, Ross, David, Greenwood, Matthew, Bradstock, Kenneth, Dalla-Pozza, Luciano, Huang, Libby, Law, Tamara, Doculara, Louise, Venn, Nicola, Ullah, Shahid, Sutton, Rosemary, Morley, Alexander A.

“…PCR is widely used to measure minimal residual disease (MRD) in lymphoid neoplasms, but its sensitivity is limited. High Adenine/Thymine PCR and High Annealing…”
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High-Annealing-Temperature PCR (HAT-PCR) Enables Sensitive Quantification of Minimal Residual Disease (MRD) in Blood in Acute Lymphoblastic Leukaemia (ALL) by Morley, Alexander A, Latham, Sue, Hughes, Elizabeth, Budgen, Bradley, Greenwood, Matthew, Bradstock, Kenneth F, Dalla-Pozza, Luciano, Law, Tamara, Doculara, Louise, Venn, Nicola, Sutton, Rosemary

“…Measurement of MRD in samples of marrow is widely used for managing patients with ALL but the clinical utility of current methods is limited by their lack of…”
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BCR-ABL1 expression, RT-qPCR and treatment decisions in chronic myeloid leukaemia by Latham, Susan, Bartley, Paul A, Budgen, Bradley, Ross, David M, Hughes, Elizabeth, Branford, Susan, White, Deborah, Hughes, Timothy P, Morley, Alexander A

“…RT-qPCR is used to quantify minimal residual disease (MRD) in chronic myeloid leukaemia (CML) in order to make decisions on treatment, but its results depend…”
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A DNA Real-Time Quantitative PCR Method Suitable for Routine Monitoring of Low Levels of Minimal Residual Disease in Chronic Myeloid Leukemia by Bartley, Paul A, Latham, Susan, Budgen, Bradley, Ross, David M, Hughes, Elizabeth, Branford, Susan, White, Deborah, Hughes, Timothy P, Morley, Alexander A

“…The BCR-ABL1 sequence has advantages over the BCR-ABL1 transcript as a molecular marker in chronic myeloid leukemia and has been used in research studies. We…”
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Sensitive monitoring of acute promyelocytic leukemia by PML-RARA DNA Q-PCR by Kommers, Ivar O., Bartley, Paul A., Budgen, Bradley, Latham, Sue, Beligaswatte, Ashanka, Supple, Shane G., Catalano, Alberto, Iland, Harry J., Morley, Alexander A., Ross, David M.

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Sensitive and Specific Measurement of Minimal Residual Disease in Acute Lymphoblastic Leukemia by Morley, Alexander A, Latham, Sue, Brisco, Michael J, Sykes, Pamela J, Sutton, Rosemary, Hughes, Elizabeth, Wilczek, Vicki, Budgen, Bradley, van Zanten, Katrina, Kuss, Bryone J, Venn, Nicola C, Norris, Murray D, Crock, Catherine, Storey, Colin, Revesz, Tamas, Waters, Keith

“…A sensitive and specific quantitative real-time polymerase chain reaction method, involving three rounds of amplification with two allele-specific…”
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Determining the Repertoire of IGH Gene Rearrangements to Develop Molecular Markers for Minimal Residual Disease in B-Lineage Acute Lymphoblastic Leukemia by Brisco, Michael J, Latham, Sue, Sutton, Rosemary, Hughes, Elizabeth, Wilczek, Vicki, van Zanten, Katrina, Budgen, Bradley, Bahar, Anita Y, Malec, Maria, Sykes, Pamela J, Kuss, Bryone J, Waters, Keith, Venn, Nicola C, Giles, Jodie E, Haber, Michelle, Norris, Murray D, Marshall, Glenn M, Morley, Alexander A

“…Molecular markers for minimal residual disease in B-lineage acute lymphoblastic leukemia were identified by determining, at the time of diagnosis, the…”
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