Search Results - "Budde, U"

von Willebrand factor: the complex molecular genetics of a multidomain and multifunctional protein by SCHNEPPENHEIM, R., BUDDE, U.

“…von Willebrand disease (VWD), the most common inherited bleeding disorder in humans, is characterised by a prolonged bleeding time due to quantitative and/or…”
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Acquired von Willebrand syndrome in congenital heart disease surgery: results from an observational case‐series by Icheva, V., Nowak‐Machen, M., Budde, U., Jaschonek, K., Neunhoeffer, F., Kumpf, M., Hofbeck, M., Schlensak, C., Wiegand, G.

“…Essentials Bleeding complications during congenital heart disease surgery in neonatal age are very common. We report the perioperative incidence of acquired…”
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Prospective evaluation of a pediatric bleeding questionnaire and the ISTH bleeding assessment tool in children and parents in routine clinical practice by BIDLINGMAIER, C., GROTE, V., BUDDE, U., OLIVIERI, M., KURNIK, K.

“…Background:  Diagnosing mild bleeding disorders (BDs) in children is difficult. Bleeding scores (BSs) have been proposed for obtaining standardized…”
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Deep intronic ‘mutations’ cause hemophilia A: application of next generation sequencing in patients without detectable mutation in F8 cDNA by Pezeshkpoor, B., Zimmer, N., Marquardt, N., Nanda, I., Haaf, T., Budde, U., Oldenburg, J., El‐Maarri, O.

“…Summary Background In a small group of typical hemophilia A (HA) patients no mutations in the F8 coding sequence (cDNA) could be found. In the current study,…”
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Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor by SADLER, J. E., BUDDE, U., EIKENBOOM, J. C. J., FAVALORO, E. J., HILL, F. G. H., HOLMBERG, L., INGERSLEV, J., LEE, C. A., LILLICRAP, D., MANNUCCI, P. M., MAZURIER, C., MEYER, D., NICHOLS, W. L., NISHINO, M., PEAKE, I. R., RODEGHIERO, F., SCHNEPPENHEIM, R., RUGGERI, Z. M., SRIVASTAVA, A., MONTGOMERY, R. R., FEDERICI, A. B.

“…von Willebrand disease (VWD) is a bleeding disorder caused by inherited defects in the concentration, structure, or function of von Willebrand factor (VWF)…”
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A quantitative analysis of bleeding symptoms in type 1 von Willebrand disease: results from a multicenter European study (MCMDM‐1 VWD) by TOSETTO, A., RODEGHIERO, F., CASTAMAN, G., GOODEVE, A., FEDERICI, A. B., BATLLE, J., MEYER, D., FRESSINAUD, E., MAZURIER, C., GOUDEMAND, J., EIKENBOOM, J., SCHNEPPENHEIM, R., BUDDE, U., INGERSLEV, J., VORLOVA, Z., HABART, D., HOLMBERG, L., LETHAGEN, S., PASI, J., HILL, F., PEAKE, I.

“…Background: A quantitative description of bleeding symptoms in type 1 von Willebrand disease (VWD) has never been reported. Objectives: The aim was to…”
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Shear‐induced unfolding activates von Willebrand factor A2 domain for proteolysis by BALDAUF, C., SCHNEPPENHEIM, R., STACKLIES, W., OBSER, T., PIECONKA, A., SCHNEPPENHEIM, S., BUDDE, U., ZHOU, J., GRÄTER, F.

“…Background: To avoid pathological platelet aggregation by von Willebrand factor (VWF), VWF multimers are regulated in size and reactivity for adhesion by…”
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Clopidogrel Resistance in Neurovascular Stenting: Correlations between Light Transmission Aggregometry, VerifyNow, and the Multiplate by Flechtenmacher, N, Kämmerer, F, Dittmer, R, Budde, U, Michels, P, Röther, J, Eckert, B

“…Clopidogrel resistance is blamed for thromboembolic complications in neurovascular stent placement. Platelet-function assays are weakly standardized. The aim…”
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Diagnostic workup of patients with acquired von Willebrand syndrome: a retrospective single‐centre cohort study by TIEDE, A., PRIESACK, J., WERWITZKE, S., BOHLMANN, K., OORTWIJN, B., LENTING, P., EISERT, R., GANSER, A., BUDDE, U.

“…Background: Diagnosis of acquired von Willebrand syndrome (AVWS) remains challenging. Diagnostic algorithms suggest the use of factor VIII (FVIII:C), von…”
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Ex vivo human placental transfer study on recombinant Von Willebrand factor (rVWF) by Pastuschek, J., Bär, C., Göhner, C., Budde, U., Leidenmuehler, P., Groten, T., Schleußner, E., Markert, U.R.

“…Deficiency or mutation of von Willebrand factor (VWF) leads to a coagulation disorder (von Willebrand disease; VWD) which requires a lifelong therapy. For…”
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Diagnosis of von Willebrand disease subtypes: implications for treatment by BUDDE, U.

“…von Willebrand disease (VWD) is a complex congenital bleeding disorder that is characterized by different quantitative and/or qualitative defects in von…”
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An international collaborative study to compare different von Willebrand factor glycoprotein Ib binding activity assays: the COMPASS‐VWF study by Szederjesi, A., Baronciani, L., Budde, U., Castaman, G., Lawrie, A. S., Liu, Y., Montgomery, R., Peyvandi, F., Schneppenheim, R., Várkonyi, A., Patzke, J., Bodó, I.

“…Essentials New VWF activity assays are increasingly used but information on their comparability is limited. This is an ISTH SSC‐organized study (expert labs, 5…”
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Identification and characterization of the elusive mutation causing the historical von Willebrand Disease type IIC Miami by Obser, T., Ledford‐Kraemer, M., Oyen, F., Brehm, M. A., Denis, C. V., Marschalek, R., Montgomery, R. R., Sadler, J. E., Schneppenheim, S., Budde, U., Schneppenheim, R.

“…Essentials Von Willebrand disease IIC Miami features high von Willebrand factor (VWF) with reduced function. We aimed to identify and characterize the elusive…”
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Detailed von Willebrand factor multimer analysis in patients with von Willebrand disease in the European study, molecular and clinical markers for the diagnosis and management of type 1 von Willebrand disease (MCMDM‐1VWD) by BUDDE, U., SCHNEPPENHEIM, R., EIKENBOOM, J., GOODEVE, A., WILL, K., DREWKE, E., CASTAMAN, G., RODEGHIERO, F., FEDERICI, A. B., BATLLE, J., PÉREZ, A., MEYER, D., MAZURIER, C., GOUDEMAND, J., INGERSLEV, J., HABART, D., VORLOVA, Z., HOLMBERG, L., LETHAGEN, S., PASI, J., HILL, F., PEAKE, I.

“…Background: Type 1 von Willebrand disease (VWD) is a congenital bleeding disorder characterized by a partial quantitative deficiency of plasma von Willebrand…”
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P-045: Dead fetus syndrome (DFS) in a high risk twin pregnancy – is laboratory testing for DIC useful? by Bergmann, F, Czwalinna, A, Groening, H, Schwerdtfeger, R, Schild, R, Budde, U

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Lupus anticoagulants associated inhibitor against factor IX in a young patient with haemophilia B by Barnbrock, A., Heller, C., Königs, C., Budde, U., Schwabe, D.

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Acquired type 2A von Willebrand syndrome caused by aortic valve disease corrects during valve surgery by Solomon, C., Budde, U., Schneppenheim, S., Czaja, E., Hagl, C., Schoechl, H., von Depka, M., Rahe-Meyer, N.

“…Aortic valve (AV) defects can destroy high molecular weight multimers (HMWM) of von Willebrand factor (VWF), leading to acquired von Willebrand syndrome (aVWS)…”
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Epidemiology and general guidelines of the management of acquired haemophilia and von Willebrand syndrome by COLLINS, P., BUDDE, U., RAND, J. H., FEDERICI, A. B., KESSLER, C. M.

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Inflammation-associated ADAMTS13 deficiency promotes formation of ultra-large von Willebrand factor by Bockmeyer, Clemens L, Claus, Ralf A, Budde, Ulrich, Kentouche, Karim, Schneppenheim, Reinhard, Losche, Wolfgang, Reinhart, Konrad, Brunkhorst, Frank M

“…1 Department of Anaesthesiology and Intensive Care Medicine, University Hospital, Friedrich-Schiller-University, Jena 2 Lab-Association Prof. Arndt and…”
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In vivo von Willebrand factor size heterogeneity in spite of the clinical deficiency of ADAMTS‐13 by DE MEYER, S. F., BUDDE, U., DECKMYN, H., VANHOORELBEKE, K.

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