Search Results - "Budatha, Madhusudhan"

Endothelial-to-mesenchymal transition drives atherosclerosis progression by Chen, Pei-Yu, Qin, Lingfeng, Baeyens, Nicolas, Li, Guangxin, Afolabi, Titilayo, Budatha, Madhusudhan, Tellides, George, Schwartz, Martin A, Simons, Michael

“…The molecular mechanisms responsible for the development and progression of atherosclerotic lesions have not been fully established. Here, we investigated the…”
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Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex by Coon, Brian G, Baeyens, Nicolas, Han, Jinah, Budatha, Madhusudhan, Ross, Tyler D, Fang, Jennifer S, Yun, Sanguk, Thomas, Jeon-Leon, Schwartz, Martin A

“…Endothelial responses to fluid shear stress are essential for vascular development and physiology, and determine the formation of atherosclerotic plaques at…”
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Fibronectin-Mediated Inflammatory Signaling Through Integrin α5 in Vascular Remodeling by Budatha, Madhusudhan, Zhang, Jiasheng, Schwartz, Martin A

“…Background Adhesion of vascular endothelial cells to the underlying basement membrane potently modulates endothelial cells to cells' inflammatory activation…”
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IL-10 from dendritic cells but not from T regulatory cells protects against cisplatin-induced nephrotoxicity by Wang, Wei Wei, Wang, Yamei, Li, Kang, Tadagavadi, Raghu, Friedrichs, William E, Budatha, Madhusudhan, Reeves, W. Brian

“…Interleukin-10 (IL-10), a cytokine with anti-inflammatory effects, is produced by renal parenchymal cells and bone marrow derived cells. Both endogenous and…”
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VE-Cadherin Phosphorylation Regulates Endothelial Fluid Shear Stress Responses through the Polarity Protein LGN by Conway, Daniel E., Coon, Brian G., Budatha, Madhusudhan, Arsenovic, Paul T., Orsenigo, Fabrizio, Wessel, Florian, Zhang, Jiasheng, Zhuang, Zhenwu, Dejana, Elisabetta, Vestweber, Dietmar, Schwartz, Martin A.

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Inhibiting Integrin α5 Cytoplasmic Domain Signaling Reduces Atherosclerosis and Promotes Arteriogenesis by Budatha, Madhusudhan, Zhang, Jiasheng, Zhuang, Zhen W., Yun, Sanguk, Dahlman, James E., Anderson, Daniel G., Schwartz, Martin A.

“…Background Fibronectin in endothelial basement membranes promotes endothelial inflammatory activation and atherosclerosis but also promotes plaque stability…”
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Dysregulation of protease and protease inhibitors in a mouse model of human pelvic organ prolapse by Budatha, Madhusudhan, Silva, Simone, Montoya, Teodoro Ignacio, Suzuki, Ayako, Shah-Simpson, Sheena, Wieslander, Cecilia Karin, Yanagisawa, Masashi, Word, Ruth Ann, Yanagisawa, Hiromi

“…Mice deficient for the fibulin-5 gene (Fbln5(-/-)) develop pelvic organ prolapse (POP) due to compromised elastic fibers and upregulation of matrix…”
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Characterization of Bacillus thuringiensis Cry toxin binding novel GPI anchored aminopeptidase from fat body of the moth Spodoptera litura by Budatha, Madhusudhan, Meur, Gargi, Kirti, P. B, Dutta Gupta, Aparna

“…Aminopeptidase N (APN) isoforms were identified as candidate receptors for Bacillus thuringiensis Cry toxins from the midgut of several insect species. In this…”
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Extracellular matrix proteases contribute to progression of pelvic organ prolapse in mice and humans by Budatha, Madhusudhan, Roshanravan, Shayzreen, Zheng, Qian, Weislander, Cecilia, Chapman, Shelby L, Davis, Elaine C, Starcher, Barry, Word, R Ann, Yanagisawa, Hiromi

“…Pelvic organ prolapse (POP) is a common condition affecting almost half of women over the age of 50. The molecular and cellular mechanisms underlying this…”
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VE-Cadherin Phosphorylation Regulates Endothelial Fluid Shear Stress Responses through the Polarity Protein LGN by Conway, Daniel E., Coon, Brian G., Budatha, Madhusudhan, Arsenovic, Paul T., Orsenigo, Fabrizio, Wessel, Florian, Zhang, Jiasheng, Zhuang, Zhenwu, Dejana, Elisabetta, Vestweber, Dietmar, Schwartz, Martin A.

“…Fluid shear stress due to blood flow on the vascular endothelium regulates blood vessel development, remodeling, physiology, and pathology [1, 2]. A complex…”
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Fibulin-4 Deficiency Results in Ascending Aortic Aneurysms: A Potential Link Between Abnormal Smooth Muscle Cell Phenotype and Aneurysm Progression by Huang, Jianbin, Davis, Elaine C, Chapman, Shelby L, Budatha, Madhusudhan, Marmorstein, Lihua Y, Word, R Ann, Yanagisawa, Hiromi

“…RATIONALE:Loss of fibulin-4 during embryogenesis results in perinatal lethality because of aneurysm rupture, and defective elastic fiber assembly has been…”
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Interaction between integrin [alpha].sub.5 and PDE4D regulates endothelial inflammatory signalling by Yun, Sanguk, Budatha, Madhusudhan, Dahlman, James E, Coon, Brian G, Cameron, Ryan T, Langer, Robert, Anderson, Daniel G

“…Atherosclerosis is primarily a disease of lipid metabolism and inflammation; however, it is also closely associated with endothelial extracellular matrix (ECM)…”
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A novel aminopeptidase in the fat body of the moth Achaea janata as a receptor for Bacillus thuringiensis Cry toxins and its comparison with midgut aminopeptidase by Budatha, Madhusudhan, Meur, Gargi, Dutta-Gupta, Aparna

“…Bacillus thuringiensis insecticidal crystal proteins bind to cell-surface receptors which represent a family of aminopeptidases [APN (aminopeptidase N)]…”
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Interaction between integrin alpha sub(5) and PDE4D regulates endothelial inflammatory signalling by Yun, Sanguk, Budatha, Madhusudhan, Dahlman, James E, Coon, Brian G, Cameron, Ryan T, Langer, Robert, Anderson, Daniel G, Baillie, George, Schwartz, Martin A

“…Atherosclerosis is primarily a disease of lipid metabolism and inflammation; however, it is also closely associated with endothelial extracellular matrix (ECM)…”
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Interaction between integrin [alpha]5 and PDE4D regulates endothelial inflammatory signalling by Yun, Sanguk, Budatha, Madhusudhan, Dahlman, James E, Coon, Brian G, Cameron, Ryan T, Langer, Robert, Anderson, Daniel G, Baillie, George, Schwartz, Martin A

“…Atherosclerosis is primarily a disease of lipid metabolism and inflammation; however, it is also closely associated with endothelial extracellular matrix (ECM)…”
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Identification and characterization of midgut proteases in Achaea janata and their implications by Budatha, Madhusudhan, Meur, Gargi, Dutta-Gupta, Aparna

“…Insect midgut proteases are excellent targets for insecticidal agents such as Bacillus thuringiensis Cry toxins and protease inhibitors. The midgut proteases…”
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Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling by Yun, Sanguk, Budatha, Madhusudhan, Dahlman, James E., Coon, Brian G., Cameron, Ryan T., Langer, Robert, Anderson, Daniel G., Baillie, George, Schwartz, Martin A.

“…Atherosclerosis is primarily a disease of lipid metabolism and inflammation; however, it is also closely associated with endothelial extracellular matrix (ECM)…”
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IL-10 from dendritic cells but not from T regulatory cells protects against cisplatin-induced nephrotoxicity by Wei Wei Wang, Yamei Wang, Kang Li, Raghu Tadagavadi, William E. Friedrichs, Madhusudhan Budatha, W. Brian Reeves, Masaki Mogi

“…Interleukin-10 (IL-10), a cytokine with anti-inflammatory effects, is produced by renal parenchymal cells and bone marrow derived cells. Both endogenous and…”
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Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex by Coon, Brian G., Baeyens, Nicolas, Han, Jinah, Budatha, Madhusudhan, Ross, Tyler D., Fang, Jennifer S., Yun, Sanguk, Thomas, Jeon-Leon, Schwartz, Martin A.

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Is hexamerin receptor a GPI-anchored protein in Achaea janata (Lepidoptera: Noctuidae)? by Budatha, Madhusudhan, Ningshen, Thuirei Jacob, Dutta-Gupta, Aparna

“…The process of uptake of hexamerins during metamorphosis from insect haemolymph by fat body cells is reminiscent of receptor-mediated endocytosis. Previously,…”
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