Search Results - "Buczynski, G"

Estimating viral titres in solutions with low viral loads by Brownie, C., Statt, J., Bauman, P., Buczynski, G., Skjolaas, K., Lee, D., Hotta, J., Roth, N.J.

“…An important consideration in the manufacture of products derived from animal or human sources is the virus reduction capacity of the manufacturing process as…”
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Inactivation of West Nile virus, vaccinia virus and viral surrogates for relevant and emergent viral pathogens in plasma-derived products by Remington, K. M., Trejo, S. R., Buczynski, G., Li, H., Osheroff, W. P., Brown, J. P., Renfrow, H., Reynolds, R., Pifat, D. Y.

“…Background and Objectives  Human plasma is the source of a wide variety of therapeutic proteins, yet it is also a potential source of viral contamination…”
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Evidence for a recycling role for Rab7 in regulating a late step in endocytosis and in retention of lysosomal enzymes in Dictyostelium discoideum by Buczynski, G, Bush, J, Zhang, L, Rodriguez-Paris, J, Cardelli, J

“…The mammalian small molecular weight GTPase Rab7 (Ypt7 in yeast) has been implicated in regulating membrane traffic at postinternalization steps along the…”
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A mutation that separates the RasG signals that regulate development and cytoskeletal function in Dictyostelium by Zhang, T, Rebstein, P J, Khosla, M, Cardelli, J, Buczynski, G, Bush, J, Spiegelman, G B, Weeks, G

“…The expression of an activated RasG, RasG-G12T, in vegetative cells of Dictyostelium discoideium produced an alteration in cell morphology. Cells underwent a…”
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A Dictystelium mutant with defective aggregate size determination by Brock, D A, Buczynski, G, Spann, T P, Wood, S A, Cardelli, J, Gomer, R H

“…Starved Dictyostelium cells aggregate into groups of roughly 10(5) cells. We have identified a gene which, when repressed by antisense transformation or…”
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Characterization of a lidless form of the molecular chaperone DnaK: deletion of the lid increases peptide on- and off-rate constants by Buczynski, G, Slepenkov, S V, Sehorn, M G, Witt, S N

“…The C-terminal, polypeptide binding domain of the 70-kDa molecular chaperone DnaK is composed of a unique lidlike subdomain that appears to hinder steric…”
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The Small M r Ras-like GTPase Rap1 and the Phospholipase C Pathway Act to Regulate Phagocytosis in Dictyostelium discoideum by Seastone, David J., Zhang, Linyi, Buczynski, Greg, Rebstein, Patrick, Weeks, Gerald, Spiegelman, George, Cardelli, James

“…The function of the small-M r Ras-like GTPase Rap1 remains largely unknown, but this protein has been demonstrated to regulate cortical actin-based morphologic…”
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Inactivation of two Dictyostelium discoideum genes, DdPIK1 and DdPIK2, encoding proteins related to mammalian phosphatidylinositide 3-kinases, results in defects in endocytosis, lysosome to postlysosome transport, actin cytoskeleton organization by Buczynski, G, Grove, B, Nomura, A, Kleve, M, Bush, J, Firtel, R.A, Cardelli, J

“…Phosphatidylinositide 3-kinases (PI 3-kinases) have been implicated in controlling cell proliferation, actin cytoskeleton organization, and the regulation of…”
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A role for a Rab4-like GTPase in endocytosis and in regulation of contractile vacuole structure and function in Dictyostelium discoideum by Bush, J, Temesvari, L, Rodriguez-Paris, J, Buczynski, G, Cardelli, J

“…The small Mr Rab4-like GTPase, RabD, localizes to the endosomal pathway and the contractile vacuole membrane system in Dictyostelium discoideum. Stably…”
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A Dictyostelium mutant with defective aggregate size determination by Brock, Debra A., Buczynski, Greg, Spann, Timothy P., Wood, Salli A., Cardelli, James, Gomer, Richard H.

“…ABSTRACT Starved Dictyostelium cells aggregate into groups of roughly 105 cells. We have identified a gene which, when repressed by antisense transformation or…”
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A Mutation That Separates the RasG Signals That Regulate Development and Cytoskeletal Function inDictyostelium by Zhang, T., Rebstein, P.J., Khosla, M., Cardelli, J., Buczynski, G., Bush, J., Spiegelman, G.B., Weeks, G.

“…The expression of an activatedRasG, RasG-G12T, in vegetative cells ofDictyostelium discoideiumproduced an alteration in cell morphology. Cells underwent a…”
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The small Mr Ras-like GTPase Rap1 and the phospholipase C pathway act to regulate phagocytosis in Dictyostelium discoideum by Seastone, D J, Zhang, L, Buczynski, G, Rebstein, P, Weeks, G, Spiegelman, G, Cardelli, J

“…The function of the small-Mr Ras-like GTPase Rap1 remains largely unknown, but this protein has been demonstrated to regulate cortical actin-based morphologic…”
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Nucleoside diphosphate kinase from Xenopus oocytes; partial purification and characterization by Buczynski, G, Potter, R L

“…We have identified and partially purified a soluble nucleoside diphosphate kinase (NDP kinase) from Xenopus laevis oocytes. The enzyme preparation can catalyze…”
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