Search Results - "Bucolo, Claudio"
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Long-term efficacy and safety profile of multiple injections of intravitreal dexamethasone implant to manage diabetic macular edema: A systematic review of real-world studies
Published in Journal of pharmacological sciences (01-12-2018)“…Systematic review of real-world studies about repeated dexamethasone intravitreal implant (DEXi) 0.7 mg in diabetic macular edema management, in order to…”
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2
Role of omega-3 fatty acids in the treatment of depressive disorders: a comprehensive meta-analysis of randomized clinical trials
Published in PloS one (07-05-2014)“…Despite omega-3 polyunsaturated fatty acids (PUFA) supplementation in depressed patients have been suggested to improve depressive symptomatology, previous…”
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3
The P2X7 receptor as a new pharmacological target for retinal diseases
Published in Biochemical pharmacology (01-04-2022)“…[Display omitted] Purinergic ionotropic receptors, such as the P2X7 receptor, are activated by extracellular adenosine triphosphate (ATP). The P2X7 receptor is…”
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4
Curcumin prevents high glucose damage in retinal pigment epithelial cells through ERK1/2‐mediated activation of the Nrf2/HO‐1 pathway
Published in Journal of cellular physiology (01-10-2019)“…To study the effects of curcumin on human retinal pigment epithelial (RPE) cells exposed to high glucose (HG) insult, we performed in vitro studies on RPE…”
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5
Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient
Published in Frontiers in pharmacology (23-12-2020)“…We report a case of central retinal artery occlusion (CRAO) in a patient with a previous history of severe COVID-19 disease. This disease has been associated…”
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6
Omega-3 Fatty Acids and Depression: Scientific Evidence and Biological Mechanisms
Published in Oxidative medicine and cellular longevity (01-01-2014)“…The changing of omega-6/omega-3 polyunsaturated fatty acids (PUFA) in the food supply of Western societies occurred over the last 150 years is thought to…”
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7
Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats
Published in Biochemical pharmacology (01-07-2012)“…Effects of eriodictyol on retinal biomarkers levels in diabetic rats Diabetic retinopathy is a complex disease that has potential involvement of inflammatory…”
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8
Carbon monoxide and the eye: Implications for glaucoma therapy
Published in Pharmacology & therapeutics (Oxford) (01-05-2011)“…In the late 1990s, the scientific community witnessed a very peculiar phenomenon: the transformation of nitric oxide (NO) from a noxious gas into a key…”
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Targeting the miRNA-155/TNFSF10 network restrains inflammatory response in the retina in a mouse model of Alzheimer’s disease
Published in Cell death & disease (05-10-2021)“…Age-related disorders, such as Alzheimer’s disease (AD) and age-related macular degeneration (AMD) share common features such as amyloid-β (Aβ) protein…”
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10
TGF-β Serum Levels in Diabetic Retinopathy Patients and the Role of Anti-VEGF Therapy
Published in International journal of molecular sciences (15-12-2020)“…Transforming growth factor β1 (TGFβ1) is a proinflammatory cytokine that has been implicated in the pathogenesis of diabetic retinopathy (DR), particularly in…”
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The immune system on the TRAIL of Alzheimer’s disease
Published in Journal of neuroinflammation (13-10-2020)“…Abstract Alzheimer’s disease (AD) is the most common form of dementia, characterized by progressive degeneration and loss of neurons in specific regions of the…”
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Modulation of Pro-Oxidant and Pro-Inflammatory Activities of M1 Macrophages by the Natural Dipeptide Carnosine
Published in International journal of molecular sciences (25-01-2020)“…Carnosine is a natural endogenous dipeptide widely distributed in mammalian tissues, existing at particularly high concentrations in the muscles and brain and…”
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13
Dopamine D3 receptor as a new pharmacological target for the treatment of depression
Published in European journal of pharmacology (05-11-2013)“…A substantial proportion of depressed patients do not respond to current antidepressant drug therapies. So far, antidepressant drugs have been developed based…”
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A New Human Blood-Retinal Barrier Model Based on Endothelial Cells, Pericytes, and Astrocytes
Published in International journal of molecular sciences (27-02-2020)“…Blood-retinal barrier (BRB) dysfunction represents one of the most significant changes occurring during diabetic retinopathy. We set up a high-reproducible…”
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Blood-retinal barrier protection against high glucose damage: The role of P2X7 receptor
Published in Biochemical pharmacology (01-10-2019)“…[Display omitted] Blood retinal barrier (BRB) breakdown is a hallmark of diabetic retinopathy, whose occurrence in early or later phases of the disease has not…”
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The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome
Published in PloS one (18-01-2019)“…The role of the hydroxycarboxylic acid receptor 2 (HCA2) in the retinal damage induced by diabetes has never been explored. In this context, the present study…”
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Short-Term Efficacy and Safety Outcomes of Brolucizumab in the Real-Life Clinical Practice
Published in Frontiers in pharmacology (04-11-2021)“…To report the early efficacy and safety outcomes of treatment with intravitreal injections of brolucizumab (IVT-B) in patients presenting neovascular…”
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Influence of Trace Elements on Neurodegenerative Diseases of The Eye-The Glaucoma Model
Published in International journal of molecular sciences (21-04-2021)“…Glaucoma is a heterogeneous group of chronic neurodegenerative disorders characterized by a relatively selective, progressive damage to the retinal ganglion…”
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Activation of the VEGF-A/ERK/PLA2 Axis Mediates Early Retinal Endothelial Cell Damage Induced by High Glucose: New Insight from an In Vitro Model of Diabetic Retinopathy
Published in International journal of molecular sciences (13-10-2020)“…Early blood retinal barrier (BRB) dysfunction induced by hyperglycemia was related to increased pro-inflammatory activity of phospholipase A2 (PLA2) and the…”
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Editorial: Chronic Inflammation and Neurodegeneration in Retinal Disease, Volume II
Published in Frontiers in pharmacology (31-05-2022)Get full text
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