Search Results - "Buckner, Lyndsey"

Unbiased Screens Show CD8+ T Cells of COVID-19 Patients Recognize Shared Epitopes in SARS-CoV-2 that Largely Reside outside the Spike Protein by Ferretti, Andrew P., Kula, Tomasz, Wang, Yifan, Nguyen, Dalena M.V., Weinheimer, Adam, Dunlap, Garrett S., Xu, Qikai, Nabilsi, Nancy, Perullo, Candace R., Cristofaro, Alexander W., Whitton, Holly J., Virbasius, Amy, Olivier, Kenneth J., Buckner, Lyndsey R., Alistar, Angela T., Whitman, Eric D., Bertino, Sarah A., Chattopadhyay, Shrikanta, MacBeath, Gavin

“…Developing effective strategies to prevent or treat coronavirus disease 2019 (COVID-19) requires understanding the natural immune response to severe acute…”
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Chlamydia trachomatis Infection of Endocervical Epithelial Cells Enhances Early HIV Transmission Events by Buckner, Lyndsey R, Amedee, Angela M, Albritton, Hannah L, Kozlowski, Pamela A, Lacour, Nedra, McGowin, Chris L, Schust, Danny J, Quayle, Alison J

“…Chlamydia trachomatis causes a predominantly asymptomatic, but generally inflammatory, genital infection that is associated with an increased risk for HIV…”
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A novel whole-bacterial enzyme linked-immunosorbant assay to quantify Chlamydia trachomatis specific antibodies reveals distinct differences between systemic and genital compartments by Albritton, Hannah L, Kozlowski, Pamela A, Lillis, Rebecca A, McGowin, Chris L, Siren, Julia D, Taylor, Stephanie N, Ibana, Joyce A, Buckner, Lyndsey R, Shen, Li, Quayle, Alison J

“…Chlamydia trachomatis (CT) is the leading sexually transmitted bacterial infection. The continued global burden of CT infection strongly predicates the need…”
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Cervical and systemic concentrations of long acting hormonal contraceptive (LARC) progestins depend on delivery method: Implications for the study of HIV transmission by Buckner, Lyndsey R, Drobnis, Erma Z, Augustine, Molly S, Rogers, Lynette K, Akers, Jill, Mott, Patricia D, Hope, Thomas J, Quayle, Alison J, Schust, Danny J

“…Progestin-only long-acting reversible contraceptives (LARCs) are increasingly popular among women seeking contraception; however, recent epidemiological…”
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The expression of YAP1 is increased in high-grade prostatic adenocarcinoma but is reduced in neuroendocrine prostate cancer by Cheng, Siyuan, Prieto-Dominguez, Nestor, Yang, Shu, Connelly, Zachary M., StPierre, Samantha, Rushing, Bryce, Watkins, Andy, Shi, Lawrence, Lakey, Meredith, Baiamonte, Lyndsey Buckner, Fazili, Tajammul, Lurie, Aubrey, Corey, Eva, Shi, Runhua, Yeh, Yunshin, Yu, Xiuping

“…Background After long-term androgen deprivation therapy, 25–30% prostate cancer (PCa) acquires an aggressive neuroendocrine (NE) phenotype. Dysregulation of…”
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Presence of antibody-dependent cellular cytotoxicity (ADCC) against SARS-CoV-2 in COVID-19 plasma by Tso, For Yue, Lidenge, Salum J, Poppe, Lisa K, Peña, Phoebe B, Privatt, Sara R, Bennett, Sydney J, Ngowi, John R, Mwaiselage, Julius, Belshan, Michael, Siedlik, Jacob A, Raine, Morgan A, Ochoa, Juan B, Garcia-Diaz, Julia, Nossaman, Bobby, Buckner, Lyndsey, Roberts, W Mark, Dean, Matthew J, Ochoa, Augusto C, West, John T, Wood, Charles

“…Neutralizing-antibody (nAb) is the major focus of most ongoing COVID-19 vaccine trials. However, nAb response against SARS-CoV-2, when present, decays rapidly…”
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Severe COVID-19 Is Characterized by an Impaired Type I Interferon Response and Elevated Levels of Arginase Producing Granulocytic Myeloid Derived Suppressor Cells by Dean, Matthew J, Ochoa, Juan B, Sanchez-Pino, Maria Dulfary, Zabaleta, Jovanny, Garai, Jone, Del Valle, Luis, Wyczechowska, Dorota, Baiamonte, Lyndsey Buckner, Philbrook, Phaethon, Majumder, Rinku, Vander Heide, Richard S, Dunkenberger, Logan, Thylur, Ramesh Puttalingaiah, Nossaman, Bobby, Roberts, W Mark, Chapple, Andrew G, Wu, Jiande, Hicks, Chindo, Collins, Jack, Luke, Brian, Johnson, Randall, Koul, Hari K, Rees, Chris A, Morris, Claudia R, Garcia-Diaz, Julia, Ochoa, Augusto C

“…COVID-19 ranges from asymptomatic in 35% of cases to severe in 20% of patients. Differences in the type and degree of inflammation appear to determine the…”
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APOL1 Risk Variants and Acute Kidney Injury in Black Americans with COVID-19 by Larsen, Christopher P, Wickman, Terrance J, Braga, Juarez R, Matute-Trochez, Luis A, Hasty, Anna E, Buckner, Lyndsey R, Arthur, John M, Haun, Randy S, Velez, Juan Carlos Q

“…Black Americans have a higher incidence of kidney disease compared with populations that do not have recent African ancestry. Two risk variants in the are…”
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Chlamydia trachomatis infection results in a modest pro-inflammatory cytokine response and a decrease in T cell chemokine secretion in human polarized endocervical epithelial cells by Buckner, Lyndsey R., Lewis, Maria E., Greene, Sheila J., Foster, Timothy P., Quayle, Alison J.

“…•A polarized endocervical epithelial cell model was infected with Chlamydia trachomatis.•C. trachomatis infection failed to yield a robust pro-inflammatory…”
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Comparison of Biaxial Biomechanical Properties of Post-menopausal Human Prolapsed and Non-prolapsed Uterosacral Ligament by Danso, Elvis K., Schuster, Jason D., Johnson, Isabella, Harville, Emily W., Buckner, Lyndsey R., Desrosiers, Laurephile, Knoepp, Leise R., Miller, Kristin S.

“…Uterosacral ligaments (USLs) provide structural support to the female pelvic floor, and a loss of USL structural integrity or biomechanical function may induce…”
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Influence of the tryptophan-indole-IFNγ axis on human genital Chlamydia trachomatis infection: role of vaginal co-infections by Aiyar, Ashok, Quayle, Alison J, Buckner, Lyndsey R, Sherchand, Shardulendra P, Chang, Theresa L, Zea, Arnold H, Martin, David H, Belland, Robert J

“…The natural history of genital Chlamydia trachomatis infections can vary widely; infections can spontaneously resolve but can also last from months to years,…”
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Potential mechanisms for increased HIV-1 transmission across the endocervical epithelium during C. trachomatis infection by Schust, Danny J, Ibana, Joyce A, Buckner, Lyndsey R, Ficarra, Mercedes, Sugimoto, Jun, Amedee, Angela M, Quayle, Alison J

“…Among the now pandemic sexually transmitted infections (STIs), Chlamydia trachomatis (C. trachomatis) is the predominant bacterial pathogen and human…”
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Structured illumination microscopy for cancer identification in diagnostic breast biopsies by Behr, Madeline, Alizadeh, Layla, Buckner-Baiamonte, Lyndsey, Roberts, Brett, Sholl, Andrew B, Brown, J Quincy

“…Breast cancer is the second most common cancer diagnosed in women in the US with almost 280,000 new cases anticipated in 2023. Currently, on-site pathology for…”
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Morphologic and molecular evaluation of Chlamydia trachomatis growth in human endocervix reveals distinct growth patterns by Lewis, Maria E, Belland, Robert J, AbdelRahman, Yasser M, Beatty, Wandy L, Aiyar, Ashok A, Zea, Arnold H, Greene, Sheila J, Marrero, Luis, Buckner, Lyndsey R, Tate, David J, McGowin, Chris L, Kozlowski, Pamela A, O'Brien, Michelle, Lillis, Rebecca A, Martin, David H, Quayle, Alison J

“…In vitro models of Chlamydia trachomatis growth have long been studied to predict growth in vivo. Alternative or persistent growth modes in vitro have been…”
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Increased inflammatory low-density neutrophils in severe obesity and effect of bariatric surgery: Results from case-control and prospective cohort studies by Sanchez-Pino, Maria Dulfary, Richardson, William S., Zabaleta, Jovanny, Puttalingaiah, Ramesh Thylur, Chapple, Andrew G., Liu, Jiao, Kim, Yonghyan, Ponder, Michelle, DeArmitt, Randi, Baiamonte, Lyndsey Buckner, Wyczechowska, Dorota, Zheng, Liqin, Al-Khami, Amir A., Garai, Jone, Martini, Rachel, Davis, Melissa, Gorham, Jessica Koller, Wooldridge, James B., Rodriguez, Paulo C., Miele, Lucio, Ochoa, Augusto C.

“…Low-density neutrophils (LDN) are increased in several inflammatory diseases and may also play a role in the low-grade chronic inflammation associated with…”
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Innate immune mediator profiles and their regulation in a novel polarized immortalized epithelial cell model derived from human endocervix by Buckner, Lyndsey R, Schust, Danny J, Ding, Jian, Nagamatsu, Takeshi, Beatty, Wandy, Chang, Theresa L, Greene, Sheila J, Lewis, Maria E, Ruiz, Bernardo, Holman, Stacey L, Spagnuolo, Rae Ann, Pyles, Richard B, Quayle, Alison J

“…Abstract The endocervix in the female reproductive tract (FRT) is susceptible to sexually transmitted pathogens such as Chlamydia trachomatis and Neisseria…”
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Membrane vesicle production by Chlamydia trachomatis as an adaptive response by Frohlich, Kyla M, Hua, Ziyu, Quayle, Alison J, Wang, Jin, Lewis, Maria E, Chou, Chau-wen, Luo, Miao, Buckner, Lyndsey R, Shen, Li

“…Bacteria have evolved specific adaptive responses to cope with changing environments. These adaptations include stress response phenotypes with dynamic…”
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Altered protein secretion of Chlamydia trachomatis in persistently infected human endocervical epithelial cells by JIN WANG, FROHLICH, Kyla M, SORRELLS, Kelly, SANTIAGO, Kerri, GUANGMING ZHONG, LI SHEN, BUCKNER, Lyndsey, QUAYLE, Alison J, MIAO LUO, XIAOGENG FENG, BEATTY, Wandy, ZIYU HUA, XIANCAI RAO, LEWIS, Maria E

“…Chlamydia trachomatis is the most common bacterial infection of the human reproductive tract globally; however, the mechanisms underlying the adaptation of the…”
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Influence of the tryptophan-indole-IFNγ axis on human genital Chlamydia trachomatis infection: role of vaginal co-infections by Aiyar, Ashok, Quayle, Alison J., Buckner, Lyndsey R., Sherchand, Shardulendra P., Chang, Theresa L., Zea, Arnold H., Martin, David H., Belland, Robert J.

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Structured illumination microscopy for cancer identification in diagnostic breast biopsies by Madeline Behr, Layla Alizadeh, Lyndsey Buckner-Baiamonte, Brett Roberts, Andrew B Sholl, J Quincy Brown

“…Breast cancer is the second most common cancer diagnosed in women in the US with almost 280,000 new cases anticipated in 2023. Currently, on-site pathology for…”
Get full text