Search Results - "Buckley, Quinton"
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1
Dynamic changes in replication timing and gene expression during lineage specification of human pluripotent stem cells
Published in Genome research (01-08-2015)“…Duplication of the genome in mammalian cells occurs in a defined temporal order referred to as its replication-timing (RT) program. RT changes dynamically…”
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Abnormal developmental control of replication-timing domains in pediatric acute lymphoblastic leukemia
Published in Genome research (01-10-2012)“…Abnormal replication timing has been observed in cancer but no study has comprehensively evaluated this misregulation. We generated genome-wide…”
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Journal Article -
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Replication-timing boundaries facilitate cell-type and species-specific regulation of a rearranged human chromosome in mouse
Published in Human molecular genetics (01-10-2012)“…In multicellular organisms, developmental changes to replication timing occur in 400-800 kb domains across half the genome. While examples of epigenetic…”
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4
Replication Timing and Pediatric Leukemia
Published in Blood (16-11-2012)“…Abstract 4609 Abnormal temporal control of replication (“replication timing”) is a universal hallmark of cancer, but the significance of this relationship is…”
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Journal Article