Search Results - "Buckley, Michael T."
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The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivo
Published in Journal of translational medicine (12-10-2007)“…Treatment options for patients with recurrent superficial bladder cancer are limited, necessitating aggressive exploration of new treatment strategies that…”
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Assessing the clinical utility of measuring Insulin-like Growth Factor Binding Proteins in tissues and sera of melanoma patients
Published in Journal of translational medicine (24-11-2008)“…Different Insulin-like Growth Factor Binding Proteins (IGFBPs) have been investigated as potential biomarkers in several types of tumors. In this study, we…”
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Digitalizing the Clinical Research Informed Consent Process: Assessing the Participant Experience in Comparison With Traditional Paper-Based Methods
Published in JCO oncology practice (01-03-2023)“…Consent processes are critical for clinical care and research and may benefit from incorporating digital strategies. We compared an electronic informed consent…”
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4
Androgen receptor overexpression in prostate cancer linked to Pur alpha loss from a novel repressor complex
Published in Cancer research (Chicago, Ill.) (15-04-2008)“…Increased androgen receptor (AR) expression and activity are pivotal for androgen-independent (AI) prostate cancer (PC) progression and resistance to…”
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Oxalic acid alters intracellular calcium in endothelial cells
Published in Atherosclerosis (01-04-2004)“…Patients with chronic renal failure (CRF) who undergo hemodialysis experience accelerated atherosclerosis and premature death. While the cause of uremic…”
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Use of an application that extracts and consolidates adverse events and concomitant medication data from clinical systems to increase clinical trial data entry efficiency, trust, and satisfaction
Published in Journal of clinical oncology (01-06-2024)“…e13651 Background: Manual abstraction of data from a site’s clinical systems to a biopharmaceutical firm’s electronic data capture (EDC) system is inefficient…”
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Integrating technology to support data management abstraction of adverse events (AE) and concomitant medications (ConMed) from the electronic health record (EHR) to sponsor electronic data capture (EDC) systems using design thinking (DT) methodology
Published in Journal of clinical oncology (01-06-2023)“…e13624 Background: Manual abstraction of data from a site’s EHR to pharmaceutical sponsor’s EDC system is labor intensive and inefficient. To reduce the time…”
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The vitamin-like dietary supplement para-aminobenzoic acid enhances the antitumor activity of ionizing radiation
Published in International journal of radiation oncology, biology, physics (01-06-2006)“…To determine whether para-aminobenzoic acid (PABA) alters the sensitivity of tumor cells to ionizing radiation in vitro and in vivo. Cellular proliferation was…”
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Patient satisfaction with cancer care delivery through telemedicine at a comprehensive cancer center across three years during and after the COVID-19 pandemic
Published in Journal of clinical oncology (01-06-2024)“…1632 Background: Telemedicine, once sparingly utilized, surged during the COVID-19 pandemic to enhance care accessibility and safety concerns. Despite initial…”
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Electronic research consents for complex early-phase I-II clinical trials integrated with telemedicine visits compared with in-person encounters
Published in Journal of clinical oncology (01-06-2022)“…1514 Background: Based on our previous research with patient satisfaction for electronic consenting (95% of 940 respondents would recommend it another…”
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MSK eConsent: Digitalizing the informed consent process to improve participant engagement and understanding
Published in Journal of clinical oncology (20-05-2020)“…Abstract only 2066 Background: eConsent was developed to digitize the research participant consenting experience with an educational engagement model. The…”
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12
Defining Methods to Improve eSource Site Start-Up Practices
Published in Contemporary clinical trials communications (01-11-2024)Get full text
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The Memorial Sloan Kettering (MSK) electronic informed consent (eIC) platform for clinical trials: An operational model and suite of tools for obtaining informed consent, and managing consent documents
Published in Journal of clinical oncology (20-05-2018)“…Abstract only…”
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The anti-inflammatory mechanism of sulfasalazine is related to adenosine release at inflamed sites
Published in The Journal of immunology (1950) (01-03-1996)“…The anti-inflammatory mechanism of sulfasalazine is not well understood. It has recently been shown that sulfasalazine inhibits…”
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