Search Results - "Buckler, Andrew J."

The emerging science of quantitative imaging biomarkers terminology and definitions for scientific studies and regulatory submissions by Kessler, Larry G, Barnhart, Huiman X, Buckler, Andrew J, Choudhury, Kingshuk Roy, Kondratovich, Marina V, Toledano, Alicia, Guimaraes, Alexander R, Filice, Ross, Zhang, Zheng, Sullivan, Daniel C

“…The development and implementation of quantitative imaging biomarkers has been hampered by the inconsistent and often incorrect use of terminology related to…”
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A Collaborative Enterprise for Multi-Stakeholder Participation in the Advancement of Quantitative Imaging by BUCKLER, Andrew J, BRESOLIN, Linda, DUNNICK, N. Reed, SULLIVAN, Daniel C

“…Medical imaging has seen substantial and rapid technical advances during the past decade, including advances in image acquisition devices, processing and…”
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Multiparametric Quantitative Imaging in Risk Prediction: Recommendations for Data Acquisition, Technical Performance Assessment, and Model Development and Validation by Huang, Erich P., Pennello, Gene, deSouza, Nandita M., Wang, Xiaofeng, Buckler, Andrew J., Kinahan, Paul E., Barnhart, Huiman X., Delfino, Jana G., Hall, Timothy J., Raunig, David L., Guimaraes, Alexander R., Obuchowski, Nancy A.

“…Combinations of multiple quantitative imaging biomarkers (QIBs) are often able to predict the likelihood of an event of interest such as death or disease…”
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Quantitative imaging biomarkers: A review of statistical methods for computer algorithm comparisons by Obuchowski, Nancy A, Reeves, Anthony P, Huang, Erich P, Wang, Xiao-Feng, Buckler, Andrew J, Kim, Hyun J (Grace), Barnhart, Huiman X, Jackson, Edward F, Giger, Maryellen L, Pennello, Gene, Toledano, Alicia Y, Kalpathy-Cramer, Jayashree, Apanasovich, Tatiyana V, Kinahan, Paul E, Myers, Kyle J, Goldgof, Dmitry B, Barboriak, Daniel P, Gillies, Robert J, Schwartz, Lawrence H, Sullivan, Daniel C

“…Quantitative biomarkers from medical images are becoming important tools for clinical diagnosis, staging, monitoring, treatment planning, and development of…”
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Comparison of 1D, 2D, and 3D Nodule Sizing Methods by Radiologists for Spherical and Complex Nodules on Thoracic CT Phantom Images by Petrick, Nicholas, PhD, Kim, Hyun J. Grace, PhD, Clunie, David, MBBS, FRACR, Borradaile, Kristin, BS, MBA, Ford, Robert, MD, Zeng, Rongping, PhD, Gavrielides, Marios A., PhD, McNitt-Gray, Michael F., PhD, Lu, Z. Q. John, PhD, Fenimore, Charles, PhD, Zhao, Binsheng, DSc, Buckler, Andrew J., MS

“…Rationale and Objectives To estimate and statistically compare the bias and variance of radiologists measuring the size of spherical and complex synthetic…”
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Quantitative Imaging Test Approval and Biomarker Qualification: Interrelated but Distinct Activities by BUCKLER, Andrew J, BRESOLIN, Linda, REED DUNNICK, N, SULLIVAN, Daniel C

“…Quantitative imaging biomarkers could speed the development of new treatments for unmet medical needs and improve routine clinical care. However, it is not…”
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Meta-analysis of the technical performance of an imaging procedure: Guidelines and statistical methodology by Huang, Erich P, Wang, Xiao-Feng, Choudhury, Kingshuk Roy, McShane, Lisa M, Gönen, Mithat, Ye, Jingjing, Buckler, Andrew J, Kinahan, Paul E, Reeves, Anthony P, Jackson, Edward F, Guimaraes, Alexander R, Zahlmann, Gudrun

“…Medical imaging serves many roles in patient care and the drug approval process, including assessing treatment response and guiding treatment decisions. These…”
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Measurement Accuracy of Atherosclerotic Plaque Structure on CT Using Phantoms to Establish Ground Truth by St. Pierre, Samantha, BS, Siegelman, Jenifer, MD, MPH, Obuchowski, Nancy A., PhD, Ma, Xiaonan, MS, Paik, David, PhD, Buckler, Andrew J., MS

“…Rationale and Objectives The purpose of this study was to characterize analytic performance of software-aided arterial vessel structure measurements across a…”
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Role of the Quantitative Imaging Biomarker Alliance in Optimizing CT for the Evaluation of Lung Cancer Screen–Detected Nodules by Mulshine, James L., MD, Gierada, David S., MD, Armato, Samuel G., PhD, Avila, Rick S., MS, Yankelevitz, David F., MD, Kazerooni, Ella A., MD, McNitt-Gray, Michael F., PhD, Buckler, Andrew J., MS, Sullivan, Daniel C., MD

“…Abstract The Quantitative Imaging Biomarker Alliance (QIBA) is a multidisciplinary consortium sponsored by the RSNA to define processes that enable the…”
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Algorithm Variability in the Estimation of Lung Nodule Volume From Phantom CT Scans: Results of the QIBA 3A Public Challenge by Athelogou, Maria, PhD, Kim, Hyun J., PhD, Dima, Alden, MS, Obuchowski, Nancy, PhD, Peskin, Adele, PhD, Gavrielides, Marios A., PhD, Petrick, Nicholas, PhD, Saiprasad, Ganesh, PhD, Colditz Colditz, Dirk, PhD, Beaumont, Hubert, PhD, Oubel, Estanislao, PhD, Tan, Yongqiang, PhD, Zhao, Binsheng, DSc, Kuhnigk, Jan-Martin, PhD, Moltz, Jan Hendrik, MS, Orieux, Guillaume, MS, Gillies, Robert J., PhD, Gu, Yuhua, PhD, Mantri, Ninad, MS, Goldmacher, Gregory, MD, PhD, Zhang, Luduan, PhD, Vega, Emilio, BS, RT (CT), Bloom, Michael, BFA, ARRT RT (CT) (CIIP), Jarecha, Rudresh, DNB, DMRE, Soza, Grzegorz, PhD, Tietjen, Christian, PhD, Takeguchi, Tomoyuki, PhD, Yamagata, Hitoshi, PhD, Peterson, Sam, MS, Masoud, Osama, PhD, Buckler, Andrew J., MS

“…Rationale and Objectives Quantifying changes in lung tumor volume is important for diagnosis, therapy planning, and evaluation of response to therapy. The aim…”
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Quantitative imaging biomarkers of coronary plaque morphology: insights from EVAPORATE by Buckler, Andrew J., Doros, Gheorghe, Kinninger, April, Lakshmanan, Suvasini, Le, Viet T., Libby, Peter, May, Heidi T., Muhlestein, Joseph B., Nelson, John R., Nicolaou, Anna, Roy, Sion K., Shaikh, Kashif, Shekar, Chandana, Tayek, John A., Zheng, Luke, Bhatt, Deepak L., Budoff, Matthew J.

“…Aims Residual cardiovascular risk persists despite statin therapy. In REDUCE-IT, icosapent ethyl (IPE) reduced total events, but the mechanisms of benefit are…”
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Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification by Seime, Till, Akbulut, Asim Cengiz, Liljeqvist, Moritz Lindquist, Siika, Antti, Jin, Hong, Winski, Greg, van Gorp, Rick H, Karlöf, Eva, Lengquist, Mariette, Buckler, Andrew J, Kronqvist, Malin, Waring, Olivia J, Lindeman, Jan H N, Biessen, Erik A L, Maegdefessel, Lars, Razuvaev, Anton, Schurgers, Leon J, Hedin, Ulf, Matic, Ljubica

“…Calcification is a prominent feature of late-stage atherosclerosis, but the mechanisms driving this process are unclear. Using a biobank of carotid…”
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Invited Commentary: Focus on Quantitative Imaging-Real Progress Is Being Made, but Much Is Left to Do by Buckler, Andrew J

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The Use of Volumetric CT as an Imaging Biomarker in Lung Cancer by Buckler, Andrew J., MS, Mulshine, James L., MD, Gottlieb, Ronald, MD, Zhao, Binsheng, DSc, Mozley, P. David, MD, Schwartz, Lawrence, MD

“…Rationale and Objectives Lung cancer is the leading cause of cancer death in the United States. Mortality outcomes have improved only modestly over the past 30…”
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Determining the Variability of Lesion Size Measurements from CT Patient Data Sets Acquired under “No Change” Conditions by McNitt-Gray, Michael F, Kim, Grace Hyun, Zhao, Binsheng, Schwartz, Lawrence H, Clunie, David, Cohen, Kristin, Petrick, Nicholas, Fenimore, Charles, Lu, Z.Q. John, Buckler, Andrew J

“…Abstract PURPOSE: To determine the variability of lesion size measurements in computed tomography data sets of patients imaged under a “no change” (“coffee…”
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Inter-Method Performance Study of Tumor Volumetry Assessment on Computed Tomography Test-Retest Data by Buckler, Andrew J., MS, Danagoulian, Jovanna, PhD, Johnson, Kjell, PhD, Peskin, Adele, PhD, Gavrielides, Marios A., PhD, Petrick, Nicholas, PhD, Obuchowski, Nancy A., PhD, Beaumont, Hubert, PhD, Hadjiiski, Lubomir, PhD, Jarecha, Rudresh, DNB, DMRE, Kuhnigk, Jan-Martin, PhD, Mantri, Ninad, MS, McNitt-Gray, Michael, PhD, Moltz, Jan H., PhD, Nyiri, Gergely, MS, Peterson, Sam, MS, Tervé, Pierre, MS, Tietjen, Christian, PhD, von Lavante, Etienne, PhD, Ma, Xiaonan, MS, St. Pierre, Samantha, BS, Athelogou, Maria, PhD

“…Rationale and objectives Tumor volume change has potential as a biomarker for diagnosis, therapy planning, and treatment response. Precision was evaluated and…”
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Coronary Computed Tomography Angiography From Clinical Uses to Emerging Technologies: JACC State-of-the-Art Review by Abdelrahman, Khaled M, Chen, Marcus Y, Dey, Amit K, Virmani, Renu, Finn, Aloke V, Khamis, Ramzi Y, Choi, Andrew D, Min, James K, Williams, Michelle C, Buckler, Andrew J, Taylor, Charles A, Rogers, Campbell, Samady, Habib, Antoniades, Charalambos, Shaw, Leslee J, Budoff, Matthew J, Hoffmann, Udo, Blankstein, Ron, Narula, Jagat, Mehta, Nehal N

“…Evaluation of coronary artery disease (CAD) using coronary computed tomography angiography (CCTA) has seen a paradigm shift in the last decade. Evidence…”
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Estimating the Precision of Quantitative Imaging Biomarkers without Test-Retest Studies by Obuchowski, Nancy A., Buckler, Andrew J.

“…A critical performance metric for any quantitative imaging biomarker is its ability to reliably generate similar values on repeat testing. This is known as the…”
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Atherosclerotic Plaque Tissue: Noninvasive Quantitative Assessment of Characteristics with Software-aided Measurements from Conventional CT Angiography by Sheahan, Malachi, Ma, Xiaonan, Paik, David, Obuchowski, Nancy A, St Pierre, Samantha, Newman, 3rd, William P, Rae, Guenevere, Perlman, Eric S, Rosol, Michael, Keith, Jr, James C, Buckler, Andrew J

“…Purpose To (a) evaluate whether plaque tissue characteristics determined with conventional computed tomographic (CT) angiography could be quantitated at higher…”
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A Novel Knowledge Representation Framework for the Statistical Validation of Quantitative Imaging Biomarkers by Buckler, Andrew J., Paik, David, Ouellette, Matt, Danagoulian, Jovanna, Wernsing, Gary, Suzek, Baris E.

“…Quantitative imaging biomarkers are of particular interest in drug development for their potential to accelerate the drug development pipeline. The lack of…”
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