Search Results - "Buckle, Tessa"

Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2 by de Gooijer, Mark C., de Vries, Nienke A., Buckle, Tessa, Buil, Levi C.M., Beijnen, Jos H., Boogerd, Willem, van Tellingen, Olaf

“…The anticancer drug temozolomide is the only drug with proven activity against high-grade gliomas and has therefore become a part of the standard treatment of…”
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High-resolution imaging and single-cell analysis via laser ablation-inductively coupled plasma-mass spectrometry for the determination of membranous receptor expression levels in breast cancer cell lines using receptor-specific hybrid tracers by Van Acker, Thibaut, Buckle, Tessa, Van Malderen, Stijn J.M., van Willigen, Danny M., van Unen, Vincent, van Leeuwen, Fijs W.B., Vanhaecke, Frank

“…This work evaluates the possibility of placement of high-resolution imaging and single-cell analysis via laser ablation-inductively coupled plasma-mass…”
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Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met by Burggraaf, Jacobus, Kamerling, Ingrid M C, Gordon, Paul B, Schrier, Lenneke, de Kam, Marieke L, Kales, Andrea J, Bendiksen, Ragnar, Indrevoll, Bård, Bjerke, Roger M, Moestue, Siver A, Yazdanfar, Siavash, Langers, Alexandra M J, Swaerd-Nordmo, Marit, Torheim, Geir, Warren, Madhuri V, Morreau, Hans, Voorneveld, Philip W, Buckle, Tessa, van Leeuwen, Fijs W B, Ødegårdstuen, Liv-Ingrid, Dalsgaard, Grethe T, Healey, Andrew, Hardwick, James C H

“…Intravenous administration of a fluorescently labeled c-Met–binding peptide enables visualization of polyps not detected using white light. Colon cancer…”
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Intraoperative Laparoscopic Fluorescence Guidance to the Sentinel Lymph Node in Prostate Cancer Patients: Clinical Proof of Concept of an Integrated Functional Imaging Approach Using a Multimodal Tracer by van der Poel, Henk G, Buckle, Tessa, Brouwer, Oscar R, Valdés Olmos, Renato A, van Leeuwen, Fijs W.B

“…Abstract Background Integration of molecular imaging and in particular intraoperative image guidance is expected to improve the surgical accuracy of…”
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Multi-Wavelength Fluorescence in Image-Guided Surgery, Clinical Feasibility and Future Perspectives by van Beurden, Florian, van Willigen, Danny M., Vojnovic, Borivoj, van Oosterom, Matthias N., Brouwer, Oscar R., der Poel, Henk G. van, Kobayashi, Hisataka, van Leeuwen, Fijs W.B., Buckle, Tessa

“…With the rise of fluorescence-guided surgery, it has become evident that different types of fluorescence signals can provide value in the surgical setting…”
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Hybrid Tracers Based on Cyanine Backbones Targeting Prostate-Specific Membrane Antigen: Tuning Pharmacokinetic Properties and Exploring Dye-Protein Interaction by Hensbergen, Albertus W, Buckle, Tessa, van Willigen, Danny M, Schottelius, Margret, Welling, Mick M, van der Wijk, Felicia A, Maurer, Tobias, van der Poel, Henk G, van der Pluijm, Gabri, van Weerden, Wytske M, Wester, Hans-Jürgen, van Leeuwen, Fijs W B

“…Prostate cancer surgery is currently being revolutionized by the use of prostate-specific membrane antigen (PSMA)-targeted radiotracers, for example,…”
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The impact of drainage pathways on the detection of nodal metastases in prostate cancer: a phase II randomized comparison of intratumoral vs intraprostatic tracer injection for sentinel node detection by Wit, Esther M. K., van Beurden, Florian, Kleinjan, Gijs H., Grivas, Nikolaos, de Korne, Clarize M., Buckle, Tessa, Donswijk, Maarten L., Bekers, Elise M., van Leeuwen, Fijs W. B., van der Poel, Henk G.

“…Introduction Previous studies indicated that location and amount of detected sentinel lymph nodes (SLNs) in prostate cancer (PCa) are influenced where…”
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Nerve Targeting via Myelin Protein Zero and the Impact of Dimerization on Binding Affinity by Berehova, Nataliia, Buckle, Tessa, van Meerbeek, Maarten P, Bunschoten, Anton, Velders, Aldrik H, van Leeuwen, Fijs W B

“…Surgically induced nerve damage is a common but debilitating side effect. By developing tracers that specifically target the most abundant protein in…”
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P-Glycoprotein and Breast Cancer Resistance Protein: Two Dominant Transporters Working Together in Limiting the Brain Penetration of Topotecan by DEVRIES, Nienkea, JIN ZHAO, KROON, Emily, BUCKLE, Tessa, BEIJNEN, Jos H, VANTELLINGEN, Olaf

“…Purpose: The brain is a pharmacologic sanctuary site, due to the presence of the blood-brain barrier (BBB). Whereas the effect of P-glycoprotein (P-gp) at the…”
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In vivo stability of supramolecular host–guest complexes monitored by dual-isotope multiplexing in a pre-targeting model of experimental liver radioembolization by Welling, Mick M., Spa, Silvia J., van Willigen, Danny M., Rietbergen, Daphne D.D., Roestenberg, Meta, Buckle, Tessa, van Leeuwen, Fijs W.B.

“…Cyclodextrin (CD)-based supramolecular interactions have been proposed as nanocarriers for drug delivery. We previously explored the use of these…”
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Restricted brain penetration of the tyrosine kinase inhibitor erlotinib due to the drug transporters P-gp and BCRP by de Vries, Nienke A., Buckle, Tessa, Zhao, Jin, Beijnen, Jos H., Schellens, Jan H. M., van Tellingen, Olaf

“…Summary Purpose Erlotinib (Tarceva®, OSI-774) is a small molecule inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. As high-grade…”
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ATP-binding cassette transporters restrict drug delivery and efficacy against brain tumors even when blood-brain barrier integrity is lost by de Gooijer, Mark C., Kemper, E. Marleen, Buil, Levi C.M., Çitirikkaya, Ceren H., Buckle, Tessa, Beijnen, Jos H., van Tellingen, Olaf

“…The impact of a compromised blood-brain barrier (BBB) on the drug treatment of intracranial tumors remains controversial. We characterize the BBB integrity in…”
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Technologic (R)Evolution Leads to Detection of More Sentinel Nodes in Patients with Melanoma in the Head and Neck Region by Berger, Danique M S, van den Berg, Nynke S, van der Noort, Vincent, van der Hiel, Bernies, Valdés Olmos, Renato A, Buckle, Tessa A, KleinJan, Gijs H, Brouwer, Oscar R, Vermeeren, Lenka, Karakullukçu, Baris, van den Brekel, Michiel W M, van de Wiel, Bart A, Nieweg, Omgo E, Balm, Alfons J M, van Leeuwen, Fijs W B, Klop, W Martin C

“…Sentinel lymph node (SN) biopsy (SNB) has proven to be a valuable tool for staging melanoma patients. Since its introduction in the early 1990s, this procedure…”
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Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1−/−/Mdr1a/1b−/− (triple-knockout) and wild-type mice by Marchetti, Serena, de Vries, Nienke A, Buckle, Tessa, Bolijn, Maria J, van Eijndhoven, Maria A J, Beijnen, Jos H, Mazzanti, Roberto, van Tellingen, Olaf, Schellens, Jan H M

“…We tested whether erlotinib hydrochloride (Tarceva, OSI-774), an orally active epidermal growth factor receptor tyrosine kinase inhibitor, is a substrate for…”
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Intraoperative visualization of nerves using a myelin protein-zero specific fluorescent tracer by Buckle, Tessa, Hensbergen, Albertus. W., van Willigen, Danny M., Bosse, Frank, Bauwens, Kevin, Pelger, Rob C. M., van Leeuwen, Fijs W. B.

“…Background Surgically induced nerve damage is a common but debilitating side effect in oncological surgery. With the aim to use fluorescence guidance to enable…”
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Advancing intraoperative magnetic tracing using 3D freehand magnetic particle imaging by Azargoshasb, Samaneh, Molenaar, Lennert, Rosiello, Giuseppe, Buckle, Tessa, van Willigen, Danny M., van de Loosdrecht, Melissa M., Welling, Mick M., Alic, Lejla, van Leeuwen, Fijs W. B., Winter, Alexander, van Oosterom, Matthias N.

“…Purpose Sentinel lymph node biopsy is a routine procedure for nodal staging in penile cancer. Most commonly, this procedure is guided by radioactive tracers,…”
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The current status and future prospects for molecular imaging-guided precision surgery by Boekestijn, Imke, van Oosterom, Matthias N, Dell'Oglio, Paolo, van Velden, Floris H P, Pool, Martin, Maurer, Tobias, Rietbergen, Daphne D D, Buckle, Tessa, van Leeuwen, Fijs W B

“…Molecular imaging technologies are increasingly used to diagnose, monitor, and guide treatment of i.e., cancer. In this review, the current status and future…”
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Synthesis and Evaluation of a Bimodal CXCR4 Antagonistic Peptide by Kuil, Joeri, Buckle, Tessa, Yuan, Hushan, van den Berg, Nynke S, Oishi, Shinya, Fujii, Nobutaka, Josephson, Lee, van Leeuwen, Fijs W. B

“…The antagonistic Ac-TZ14011 peptide, which binds to the chemokine receptor 4, has been labeled with a multifunctional single attachment point reagent that…”
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The effect of P-gp (Mdr1a/1b), BCRP (Bcrp1) and P-gp/BCRP inhibitors on the in vivo absorption, distribution, metabolism and excretion of imatinib by Oostendorp, Roos L., Buckle, Tessa, Beijnen, Jos H., van Tellingen, Olaf, Schellens, Jan H. M.

“…Summary Imatinib is transported by P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP), however, the exact impact of these transporters on…”
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A Truncated 14-Amino-Acid Myelin Protein-Zero-Targeting Peptide for Fluorescence-Guided Nerve-Preserving Surgery by Berehova, Nataliia, van Meerbeek, Maarten P, Azargoshasb, Samaneh, van Willigen, Danny M, Slof, Leon J, Navaei Lavasani, Saaedeh, van Oosterom, Matthias N, van Leeuwen, Fijs W B, Buckle, Tessa

“…The occurrence of accidental nerve damage during surgery and the increasing application of image guidance during head-and-neck surgery have highlighted the…”
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