Search Results - "Buckle, Malcolm"

H-NS cooperative binding to high-affinity sites in a regulatory element results in transcriptional silencing by Travers, Andrew, Badaut, Cyril, Bouffartigues, Emeline, Rimsky, Sylvie, Buckle, Malcolm

“…H-NS is a protein of the bacterial nucleoid involved in DNA compaction and transcription regulation. In vivo, H-NS selectively silences specific genes of the…”
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Nucleosome assembly and disassembly pathways in vitro by Hatakeyama, Akiko, Shymko, Yuliia, Hartmann, Brigitte, Retureau, Romain, Nogues, Claude, Pasi, Marco, Buckle, Malcolm

“…Structural fluctuations of nucleosomes modulate the access to internal DNA in eukaryotic cells; clearly characterisation of this fundamental process is crucial…”
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High-affinity DNA binding sites for H-NS provide a molecular basis for selective silencing within proteobacterial genomes by Lang, Benjamin, Blot, Nicolas, Bouffartigues, Emeline, Buckle, Malcolm, Geertz, Marcel, Gualerzi, Claudio O, Mavathur, Ramesh, Muskhelishvili, Georgi, Pon, Cynthia L, Rimsky, Sylvie, Stella, Stefano, Babu, M. Madan, Travers, Andrew

“…The global transcriptional regulator H-NS selectively silences bacterial genes associated with pathogenicity and responses to environmental insults. Although…”
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Ribosome Evolution and Structural Capacitance by Buckle, Ashley M, Buckle, Malcolm

“…In addition to the canonical loss-of-function mutations, mutations in proteins may additionally result in gain-of-function through the binary activation of…”
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Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis by Kass, Itamar, Hoke, David E, Costa, Mauricio G S, Reboul, Cyril F, Porebski, Benjamin T, Cowieson, Nathan P, Leh, Hervé, Pennacchietti, Eugenia, McCoey, Julia, Kleifeld, Oded, Borri Voltattorni, Carla, Langley, David, Roome, Brendan, Mackay, Ian R, Christ, Daniel, Perahia, David, Buckle, Malcolm, Paiardini, Alessandro, De Biase, Daniela, Buckle, Ashley M

“…The human neuroendocrine enzyme glutamate decarboxylase (GAD) catalyses the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) using…”
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Efficient antifouling surface for quantitative surface plasmon resonance based biosensor analysis by Nogues, Claude, Leh, Hervé, Lautru, Joseph, Delelis, Olivier, Buckle, Malcolm

“…Non-specific binding to biosensor surfaces is a major obstacle to quantitative analysis of selective retention of analytes at immobilized target molecules…”
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Highly mutagenic exocyclic DNA adducts are substrates for the human nucleotide incision repair pathway by Prorok, Paulina, Saint-Pierre, Christine, Gasparutto, Didier, Fedorova, Olga S, Ishchenko, Alexander A, Leh, Hervé, Buckle, Malcolm, Tudek, Barbara, Saparbaev, Murat

“…Oxygen free radicals induce lipid peroxidation (LPO) that damages and breaks polyunsaturated fatty acids in cell membranes. LPO-derived aldehydes and…”
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DNA base pair resolution measurements using resonance energy transfer efficiency in lanthanide doped nanoparticles by Delplanque, Aleksandra, Wawrzynczyk, Dominika, Jaworski, Pawel, Matczyszyn, Katarzyna, Pawlik, Krzysztof, Buckle, Malcolm, Nyk, Marcin, Nogues, Claude, Samoc, Marek

“…Lanthanide-doped nanoparticles are of considerable interest for biodetection and bioimaging techniques thanks to their unique chemical and optical properties…”
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SPRi-based strategy to identify specific biomarkers in systemic lupus erythematosus, rheumatoid arthritis and autoimmune hepatitis by Beleoken, Elvire, Leh, Hervé, Arnoux, Armelle, Ducot, Béatrice, Nogues, Claude, De Martin, Eleonora, Johanet, Catherine, Samuel, Didier, Mustafa, Mohammad Zahid, Duclos-Vallée, Jean-Charles, Buckle, Malcolm, Ballot, Eric

“…Heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 is a target for antinuclear autoantibodies in systemic Lupus erythematosus (SLE), rheumatoid arthritis…”
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Fast Active Merging of Microdroplets in Microfluidic Chambers Driven by Photo-Isomerisation of Azobenzene Based Surfactants by Hayat, Zain, Bchellaoui, Nizar, Deo, Claire, Métivier, Rémi, Bogliotti, Nicolas, Xie, Juan, Buckle, Malcolm, El Abed, Abdel I

“…In this work, we report on the development of a newly synthesized photoactive reversible azobenzene derived surfactant polymer, which enables active and fast…”
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Real-Time Characterization of Intermediates in the Pathway to Open Complex Formation by Escherichia coli RNA Polymerase at the T7A1 Promoter by Sclavi, Bianca, Zaychikov, Evgeny, Rogozina, Anastasia, Walther, Ferdinand, Buckle, Malcolm, Heumann, Hermann, Geiduschek, E. Peter

“…We have used time-resolved x-ray-generated hydroxyl radical footprinting to directly characterize, at single-nucleotide resolution, several intermediates in…”
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Characterisation of peptide microarrays for studying antibody-antigen binding using surface plasmon resonance imagery by Nogues, Claude, Leh, Hervé, Langendorf, Christopher G, Law, Ruby H P, Buckle, Ashley M, Buckle, Malcolm

“…Non-specific binding to biosensor surfaces is a major obstacle to quantitative analysis of selective retention of analytes at immobilized target molecules…”
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A molecular mechanism for the repression of transcription by the H‐NS protein by Rimsky, Sylvie, Zuber, Florent, Buckle, Malcolm, Buc, Henri

“…The H‐NS protein is a major component of the bacterial nucleoid and plays a crucial role in the global gene regulation of enteric bacteria. Although H‐NS does…”
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Correction: Highly Mutagenic Exocyclic DNA Adducts Are Substrates for the Human Nucleotide Incision Repair Pathway by Prorok, Paulina, Saint-Pierre, Christine, Gasparutto, Didier, Fedorova, Olga S., Ishchenko, Alexander A., Leh, Hervé, Buckle, Malcolm, Tudek, Barbara, Saparbaev, Murat

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E2 Proteins from High- and Low-Risk Human Papillomavirus Types Differ in Their Ability To Bind p53 and Induce Apoptotic Cell Death by PARISH, Joanna L, KOWALCZYK, Anna, CHEN, Hsin-Tien, ROEDER, Geraldine E, SESSIONS, Richard, BUCKLE, Malcolm, GASTON, Kevin

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Recognition of a Conserved Class of RNA Tetraloops by Saccharomyces cerevisiae RNase III by Chanfreau, Guillaume, Buckle, Malcolm, Jacquier, Alain

“…Ribonucleases III are double-stranded RNA (dsRNA) endonucleases required for the processing of a large number of prokaryotic and eukaryotic transcripts…”
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Mechanism of Transcriptional Activation by FIS: Role of Core Promoter Structure and DNA Topology by Auner, Helge, Buckle, Malcolm, Deufel, Annette, Kutateladze, Tamara, Lazarus, Linda, Mavathur, Ramesh, Muskhelishvili, Georgi, Pemberton, Iain, Schneider, Robert, Travers, Andrew

“…The Escherichia coli DNA architectural protein FIS activates transcription from stable RNA promoters on entry into exponential growth and also reduces the…”
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Study of Bacteriophage T4-encoded Dam DNA (Adenine-N6)-methyltransferase Binding with Substrates by Rapid Laser UV Cross-linking by Evdokimov, Alexey A., Sclavi, Bianca, Zinoviev, Victor V., Malygin, Ernst G., Hattman, Stanley, Buckle, Malcolm

“…DNA methyltransferases of the Dam family (including bacteriophage T4-encoded Dam DNA (adenine-N6)-methyltransferase (T4Dam)) catalyze methyl group transfer…”
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The Metal Ion-induced Cooperative Binding of HIV-1 Integrase to DNA Exhibits a Marked Preference for Mn(II) Rather than Mg(II) (∗) by Pemberton, Iain K., Buckle, Malcolm, Buc, Henri

“…In this investigation, we examine the interaction between the human immunodeficiency virus type I integrase and oligonucleotides that reflect the sequences of…”
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Bacteriophage T4Dam DNA-(Adenine-N6)-methyltransferase by Malygin, Ernst G., Sclavi, Bianca, Zinoviev, Victor V., Evdokimov, Alexey A., Hattman, Stanley, Buckle, Malcolm

“…We analyzed pre-steady state and single turnover kinetics of bacteriophage T4Dam DNA-(adenine-N6)-methyltransferase-mediated methyl group transfer from…”
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