Search Results - "Buckland, Michael E"

Exosomal microRNA signatures in multiple sclerosis reflect disease status by Ebrahimkhani, Saeideh, Vafaee, Fatemeh, Young, Paul E., Hur, Suzy S. J., Hawke, Simon, Devenney, Emma, Beadnall, Heidi, Barnett, Michael H., Suter, Catherine M., Buckland, Michael E.

“…Multiple Sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS). There is currently no single definitive test for…”
Get full text

Potentially toxic elements in the brains of people with multiple sclerosis by Pamphlett, Roger, Buckland, Michael E., Bishop, David P.

“…Potentially toxic elements such as lead and aluminium have been proposed to play a role in the pathogenesis of multiple sclerosis (MS), since their neurotoxic…”
Get full text

Comprehensive proteome profiling of glioblastoma-derived extracellular vesicles identifies markers for more aggressive disease by Mallawaaratchy, Duthika M., Hallal, Susannah, Russell, Ben, Ly, Linda, Ebrahimkhani, Saeideh, Wei, Heng, Christopherson, Richard I., Buckland, Michael E., Kaufman, Kimberley L.

“…Extracellular vesicles (EVs) play key roles in glioblastoma (GBM) biology and represent novel sources of biomarkers that are detectable in the peripheral…”
Get full text

Understanding the extracellular vesicle surface for clinical molecular biology by Hallal, Susannah, Tűzesi, Ágota, Grau, Georges E., Buckland, Michael E., Alexander, Kimberley L.

“…Extracellular vesicles (EVs) are lipid‐membrane enclosed nanoparticles that play significant roles in health and disease. EVs are abundant in body fluids and…”
Get full text

Applying the Bradford Hill Criteria for Causation to Repetitive Head Impacts and Chronic Traumatic Encephalopathy by Nowinski, Christopher J, Bureau, Samantha C, Buckland, Michael E, Curtis, Maurice A, Daneshvar, Daniel H, Faull, Richard L M, Grinberg, Lea T, Hill-Yardin, Elisa L, Murray, Helen C, Pearce, Alan J, Suter, Catherine M, White, Adam J, Finkel, Adam M, Cantu, Robert C

“…Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with a history of repetitive head impacts (RHI). CTE was described in boxers…”
Get full text

Chronic traumatic encephalopathy in a female ex-professional Australian rules footballer by Suter, Catherine M., Affleck, Andrew J., Pearce, Alan J., Junckerstorff, Reimar, Lee, Maggie, Buckland, Michael E.

Get full text

Epigenetic profiling for the molecular classification of metastatic brain tumors by Orozco, Javier I. J., Knijnenburg, Theo A., Manughian-Peter, Ayla O., Salomon, Matthew P., Barkhoudarian, Garni, Jalas, John R., Wilmott, James S., Hothi, Parvinder, Wang, Xiaowen, Takasumi, Yuki, Buckland, Michael E., Thompson, John F., Long, Georgina V., Cobbs, Charles S., Shmulevich, Ilya, Kelly, Daniel F., Scolyer, Richard A., Hoon, Dave S. B., Marzese, Diego M.

“…Optimal treatment of brain metastases is often hindered by limitations in diagnostic capabilities. To meet this challenge, here we profile DNA methylomes of…”
Get full text

Epigenetic differences between monozygotic twins discordant for amyotrophic lateral sclerosis (ALS) provide clues to disease pathogenesis by Young, Paul E, Kum Jew, Stephen, Buckland, Michael E, Pamphlett, Roger, Suter, Catherine M

“…Amyotrophic lateral sclerosis (ALS) is a devastating late-onset neurodegenerative disorder in which only a small proportion of patients carry an identifiable…”
Get full text

Deep Sequencing of Small RNAs from Neurosurgical Extracellular Vesicles Substantiates miR-486-3p as a Circulating Biomarker that Distinguishes Glioblastoma from Lower-Grade Astrocytoma Patients by Hallal, Susannah, Ebrahim Khani, Saeideh, Wei, Heng, Lee, Maggie Yuk Ting, Sim, Hao-Wen, Sy, Joanne, Shivalingam, Brindha, Buckland, Michael E, Alexander-Kaufman, Kimberley L

“…Extracellular vesicles (EVs) play key roles in glioblastoma (GBM; astrocytoma grade IV) biology and are novel sources of biomarkers. EVs released from GBM…”
Get full text

Deep sequencing of circulating exosomal microRNA allows non-invasive glioblastoma diagnosis by Ebrahimkhani, Saeideh, Vafaee, Fatemeh, Hallal, Susannah, Wei, Heng, Lee, Maggie Yuk T., Young, Paul E., Satgunaseelan, Laveniya, Beadnall, Heidi, Barnett, Michael H., Shivalingam, Brindha, Suter, Catherine M., Buckland, Michael E., Kaufman, Kimberley L.

“…Exosomes are nano-sized extracellular vesicles released by many cells that contain molecules characteristic of their cell of origin, including microRNA…”
Get full text

Concentrations of toxic metals and essential trace elements vary among individual neurons in the human locus ceruleus by Pamphlett, Roger, Mak, Rachel, Lee, Joonsup, Buckland, Michael E, Harding, Antony J, Kum Jew, Stephen, Paterson, David J, Jones, Michael W M, Lay, Peter A

“…Damage to locus ceruleus neurons could play a part in the pathogenesis of neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and…”
Get full text

IDH1 and IDH2 mutations in postoperative diffuse glioma-associated epilepsy by Neal, Andrew, Kwan, Patrick, O'Brien, Terence John, Buckland, Michael E., Gonzales, Michael, Morokoff, Andrew

“…Isocitrate dehydrogenase 1 and 2 mutations (IDH1/2) have an established association with preoperative seizures in patients with grades II–IV diffuse gliomas…”
Get full text

Chronic Traumatic Encephalopathy as a Preventable Environmental Disease by Buckland, Michael E., Affleck, Andrew J., Pearce, Alan J., Suter, Catherine M.

“…In this Perspective we explore the evolution of our understanding of chronic traumatic encephalopathy (CTE) and its relationship with repetitive head injury…”
Get full text

Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity by Cropley, Jennifer E, Eaton, Sally A, Aiken, Alastair, Young, Paul E, Giannoulatou, Eleni, Ho, Joshua W.K, Buckland, Michael E, Keam, Simon P, Hutvagner, Gyorgy, Humphreys, David T, Langley, Katherine G, Henstridge, Darren C, Martin, David I.K, Febbraio, Mark A, Suter, Catherine M

“…Abstract Objective Parental obesity can induce metabolic phenotypes in offspring independent of the inherited DNA sequence. Here we asked whether such…”
Get full text

Integrated Genomic Classification of Melanocytic Tumors of the Central Nervous System Using Mutation Analysis, Copy Number Alterations, and DNA Methylation Profiling by Griewank, Klaus G, Koelsche, Christian, van de Nes, Johannes A P, Schrimpf, Daniel, Gessi, Marco, Möller, Inga, Sucker, Antje, Scolyer, Richard A, Buckland, Michael E, Murali, Rajmohan, Pietsch, Torsten, von Deimling, Andreas, Schadendorf, Dirk

“…In the central nervous system, distinguishing primary leptomeningeal melanocytic tumors from melanoma metastases and predicting their biological behavior…”
Get full text

The emerging clinical potential of circulating extracellular vesicles for non-invasive glioma diagnosis and disease monitoring by Hallal, Susannah, Ebrahimkhani, Saeideh, Shivalingam, Brindha, Graeber, Manuel B., Kaufman, Kimberley L., Buckland, Michael E.

“…Diffuse gliomas (grades II–IV) are amongst the most frequent and devastating primary brain tumours of adults. Currently, patients are monitored by clinical…”
Get full text

Implications of Concurrent IDH1 and IDH2 Mutations on Survival in Glioma—A Case Report and Systematic Review by Yuile, Alexander, Satgunaseelan, Laveniya, Wei, Joe, Kastelan, Marina, Back, Michael F., Lee, Maggie, Wei, Heng, Buckland, Michael E., Lee, Adrian, Wheeler, Helen R.

“…Both IDH1 (isocitrate dehydrogenase 1) and IDH2 (isocitrate dehydrogenase 2) mutations play a vital role in the development of gliomas through disruption of…”
Get full text

Chronic traumatic encephalopathy in two former Australian National Rugby League players by Buckland, Michael E, Sy, Joanne, Szentmariay, Istvan, Kullen, Alexandra, Lee, Maggie, Harding, Antony, Halliday, Glenda, Suter, Catherine M

“…Keywords: Chronic traumatic encephalopathy, CTE, Rugby league, Tau, ARTAG…”
Get full text

Chronic Neurophysiological Effects of Repeated Head Trauma in Retired Australian Male Sport Athletes by Pearce, Alan J, Kidgell, Dawson J, Tommerdahl, Mark A, Frazer, Ashlyn K, Rist, Billymo, Mobbs, Rowena, Batchelor, Jennifer, Buckland, Michael E

“…This study investigated the somatosensory and corticomotor physiology of retired contact sport athletes with a history of repeated concussion/subconcussion…”
Get full text

Persistence of a T Cell Infiltrate in Human Ganglia Years After Herpes Zoster and During Post-herpetic Neuralgia by Sutherland, Jeremy P., Steain, Megan, Buckland, Michael E., Rodriguez, Michael, Cunningham, Anthony L., Slobedman, Barry, Abendroth, Allison

“…Varicella-zoster virus (VZV) is a human herpesvirus which causes varicella (chicken pox) during primary infection, establishes latency in sensory ganglia, and…”
Get full text