Search Results - "Buckinx, An"
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Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice
Published in Nature communications (16-09-2023)“…Microglia, the innate immune cells of the central nervous system, actively participate in brain development by supporting neuronal maturation and refining…”
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Psychedelic-Induced Serotonin 2A Receptor Downregulation Does Not Predict Swim Stress Coping in Mice
Published in International journal of molecular sciences (04-12-2022)“…Serotoninergic psychedelics such as psilocybin have been reported to elicit a long-lasting reduction in depressive symptoms. Although the main target for…”
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Targeting the Ghrelin Receptor as a Novel Therapeutic Option for Epilepsy
Published in Biomedicines (27-12-2021)“…Epilepsy is a neurological disease affecting more than 50 million individuals worldwide. Notwithstanding the availability of a broad array of antiseizure drugs…”
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Exploring Refinement Strategies for Single Housing of Male C57BL/6JRj Mice: Effect of Cage Divider on Stress-Related Behavior and Hypothalamic-Pituitary-Adrenal-Axis Activity
Published in Frontiers in behavioral neuroscience (28-10-2021)“…Introduction: Single housing of laboratory mice is a common practice to meet experimental needs, or to avoid intermale aggression. However, single housing is…”
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Differential Effects of a Full and Biased Ghrelin Receptor Agonist in a Mouse Kindling Model
Published in International journal of molecular sciences (20-05-2019)“…The ghrelin system has received substantial recognition as a potential target for novel anti-seizure drugs. Ghrelin receptor (ghrelin-R) signaling is complex,…”
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6
Microglial metabolic flexibility: emerging roles for lactate
Published in Trends in endocrinology and metabolism (01-03-2022)“…Microglia, the resident macrophages of the central nervous system (CNS), play important functions in the healthy and diseased brain. In the emerging field of…”
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Chemogenetic modulation of astrocytes and microglia: State‐of‐the‐art and implications in neuroscience
Published in Glia (01-09-2023)“…Insights into the role astrocytes and microglia play in normal and diseased brain functioning has expanded drastically over the last decade. Recently,…”
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The Barnes Maze Task Reveals Specific Impairment of Spatial Learning Strategy in the Intrahippocampal Kainic Acid Model for Temporal Lobe Epilepsy
Published in Neurochemical research (01-03-2019)“…Temporal lobe epilepsy (TLE) is an acquired form of focal epilepsy, in which patients not only suffer from unprovoked, devastating seizures, but also from…”
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Translational potential of the ghrelin receptor agonist macimorelin for seizure suppression in pharmacoresistant epilepsy
Published in European journal of neurology (01-09-2021)“…Background Current drugs for epilepsy affect seizures, but no antiepileptogenic or disease‐modifying drugs are available that prevent or slow down…”
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The effect of housing conditions on working memory and anxiety in male C57BL/6 mice
Published in Frontiers in neuroscience (2019)“…Abstract only…”
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CHEMOGENETIC MODULATION OF ASTROCYTES IN A MODEL FOR TEMPORAL LOBE EPILEPSY
Published in Frontiers in neuroscience (2019)“…Abstract only…”
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Wireless telemetry as an ideal tool for continuous intrahippocampal EEG recording in chronic epilepsy mouse models
Published in Frontiers in neuroscience (2017)“…Abstract only…”
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