Search Results - "Buck, Leslie T."

Alfaxalone is an effective anesthetic for the electrophysiological study of anoxia-tolerance mechanisms in western painted turtle pyramidal neurons by Suganthan, Haushe, Stefano, Domenic Di, Buck, Leslie T

“…Anoxia in the mammalian brain leads to hyper-excitability and cell death; however, this cascade of events does not occur in the anoxia-tolerant brain of the…”
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Skeletal muscle metabolism and contraction performance regulation by teneurin C-terminal-associated peptide-1 by Hogg, David W, Reid, Andrea L, Dodsworth, Thomas L, Chen, Yani, Reid, Ross M, Xu, Mei, Husic, Mia, Biga, Peggy R, Slee, Andrew, Buck, Leslie T, Barsyte-Lovejoy, Dalia, Locke, Marius, Lovejoy, David A

“…Skeletal muscle regulation is responsible for voluntary muscular movement in vertebrates. The genes of two essential proteins, teneurins and latrophilins…”
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Transcriptomic Responses of the Heart and Brain to Anoxia in the Western Painted Turtle by Keenan, Sarah W, Hill, Craig A, Kandoth, Cyriac, Buck, Leslie T, Warren, Daniel E

“…Painted turtles are the most anoxia-tolerant tetrapods known, capable of surviving without oxygen for more than four months at 3°C and 30 hours at 20°C. To…”
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Exposure to low temperature prepares the turtle brain to withstand anoxic environments during overwintering by Lari, Ebrahim, Buck, Leslie T.

“…ABSTRACT In most vertebrates, anoxia drastically reduces the production of the essential adenosine triphosphate (ATP) to power its many necessary functions,…”
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Hypoxia tolerance in reptiles, amphibians, and fishes: life with variable oxygen availability by Bickler, Philip E, Buck, Leslie T

“…The ability of fishes, amphibians, and reptiles to survive extremes of oxygen availability derives from a core triad of adaptations: profound metabolic…”
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Time-dependent expression of heat shock proteins 70 and 90 in tissues of the anoxic western painted turtle by Ramaglia, Valeria, Buck, Leslie T

“…Expression of the constitutive Hsp73, inducible Hsp72 and Hsp90 was investigated in brain, heart, liver and skeletal muscle of the anoxia-tolerant western…”
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The hypoxia-tolerant vertebrate brain: Arresting synaptic activity by Buck, Leslie T., Pamenter, Matthew E.

“…The ion channel arrest hypothesis has been the foundation of three decades of research into the underlying mechanisms of hypoxia/anoxia tolerance in several…”
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Sensing and surviving hypoxia in vertebrates by Jonz, Michael G., Buck, Leslie T., Perry, Steve F., Schwerte, Thorsten, Zaccone, Giacomo

“…Surviving hypoxia is one of the most critical challenges faced by vertebrates. Most species have adapted to changing levels of oxygen in their environment with…”
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Endogenous GABAA and GABAB receptor-mediated electrical suppression is critical to neuronal anoxia tolerance by Pamenter, Matthew E, Hogg, David W, Ormond, Jake, Shin, Damian S, Woodin, Melanie A, Buck, Leslie T

“…Anoxic insults cause hyperexcitability and cell death in mammalian neurons. Conversely, in anoxia-tolerant turtle brain, spontaneous electrical activity is…”
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Evolution of a novel regulatory mechanism of hypoxia inducible factor in hypoxia-tolerant electric fishes by Elbassiouny, Ahmed A., Buck, Leslie T., Abatti, Luis E., Mitchell, Jennifer A., Crampton, William G.R., Lovejoy, Nathan R., Chang, Belinda S.W.

“…Hypoxia is a significant source of metabolic stress that activates many cellular pathways involved in cellular differentiation, proliferation, and cell death…”
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Hypoxia-Induced Silencing of NMDA Receptors in Turtle Neurons by Bickler, Philip E, Donohoe, Paul H, Buck, Leslie T

“…Hypoxia-induced suppression of NMDA receptors (NMDARs) in western painted turtle (Chrysemys picta) cortical neurons may be critical for surviving months of…”
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Decreases in mitochondrial reactive oxygen species initiate GABA(A) receptor-mediated electrical suppression in anoxia-tolerant turtle neurons by Hogg, David W, Pamenter, Matthew E, Dukoff, David J, Buck, Leslie T

“…Anoxia induces hyper-excitability and cell death in mammalian brain but in the anoxia-tolerant western painted turtle (Chrysemys picta bellii) neuronal…”
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Decreases in mitochondrial reactive oxygen species initiate GABAA receptor‐mediated electrical suppression in anoxia‐tolerant turtle neurons by Hogg, David W., Pamenter, Matthew E., Dukoff, David J., Buck, Leslie T.

“…Key points Anoxia induces hyper‐excitability and cell death in mammalian brain but in the western painted turtle (Chrysemys picta bellii) enhanced GABA…”
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Excitatory actions of GABA mediate severe-hypoxia-induced depression of neuronal activity in the pond snail (Lymnaea stagnalis) by Cheung, Una, Moghaddasi, Mehrnoush, Hall, Hannah L, Smith, J J B, Buck, Leslie T, Woodin, Melanie A

“…To characterize the effect of severe hypoxia on neuronal activity, long-term intracellular recordings were made from neurones in the isolated central ring…”
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Taurine activates glycine and GABAA receptor currents in anoxia-tolerant painted turtle pyramidal neurons by Miles, Ashley Rebecca, Hawrysh, Peter John, Hossein-Javaheri, Nariman, Buck, Leslie Thomas

“…Unlike anoxia-intolerant mammals, painted turtles can survive extended periods without oxygen. This is partly accomplished by an anoxia-mediated increase in…”
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Stellate and pyramidal neurons in goldfish telencephalon respond differently to anoxia and GABA receptor inhibition by Hossein-Javaheri, Nariman, Wilkie, Michael P, Lado, Wudu E, Buck, Leslie T

“…With oxygen deprivation, the mammalian brain undergoes hyper-activity and neuronal death while this does not occur in the anoxia-tolerant goldfish ( ). Anoxic…”
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Matching cellular metabolic supply and demand in energy-stressed animals by Staples, James F., Buck, Leslie T.

“…Certain environmental stressors can impair cellular ATP production to the point of harming or even killing an animal. Some exceptional animals employ…”
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Assessment of anoxia tolerance and photoperiod dependence of GABAergic polarity in the pond snail Lymnaea stagnalis by Buck, Leslie T., Bond, Hilary C., Malik, Aqsa

“…The pond snail Lymnaea stagnalis is reported to be anoxia-tolerant and if the tolerance mechanism is similar to that of the anoxia-tolerant painted turtle,…”
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Proteomic changes in the brain of the western painted turtle (Chrysemys picta bellii) during exposure to anoxia by Smith, Richard W., Cash, Phil, Hogg, David W., Buck, Leslie T.

“…During anoxia, overall protein synthesis is almost undetectable in the brain of the western painted turtle. The aim of this investigation was to address the…”
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Endogenous GABA(A) and GABA(B) receptor-mediated electrical suppression is critical to neuronal anoxia tolerance by Pamenter, Matthew E, Hogg, David W, Ormond, Jake, Shin, Damian S, Woodin, Melanie A, Buck, Leslie T

“…Anoxic insults cause hyperexcitability and cell death in mammalian neurons. Conversely, in anoxia-tolerant turtle brain, spontaneous electrical activity is…”
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