Search Results - "Buchynskyy, A"
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Fluorescence correlation spectroscopy as a new method for the investigation of aptamer/target interactions
Published in Biological chemistry (01-03-2001)“…Fluorescence correlation spectroscopy is an attractive tool for monitoring molecular interactions in solution. We report here a new and highly sensitive method…”
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A Surface Plasmon Resonance Analysis of the Interaction between the Antibiotic Moenomycin A and Penicillin-Binding Protein 1b
Published in Chembiochem : a European journal of chemical biology (03-06-2002)“…The antibiotic moenomycin A inhibits the biosynthesis of peptidoglycan, the main structural polymer of the bacterial cell wall. The inhibition is based on a…”
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Synthesis of Neo-Peptidoglycans: An Unexpected Activity of Proteases
Published in Angewandte Chemie International Edition (02-08-2002)“…Carbohydrate coupling at any desired peptide carboxylate moiety is possible with a highly selective biocatalytic route for the synthesis of…”
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Membrane Anchoring and Intervesicle Transfer of a Derivative of the Antibiotic Moenomycin A
Published in Angewandte Chemie International Edition (16-12-1999)“…The anchoring of moenomycin A (1) to the bacterial cell cytoplasmic membrane is essential for its biological activity. The first details of the strength of…”
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Studies on the interaction of the antibiotic moenomycin A with the enzyme Penicillin-binding protein 1b
Published in Bioorganic & medicinal chemistry (03-07-2003)“…The interaction of a moenomycin derivative with the enzyme penicillin binding protein 1b (PBP 1b) has been studied by means of STD NMR. The results obtained…”
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Synthesis of Fluorescent Derivatives of the Antibiotic Moenomycin A
Published in European journal of organic chemistry (01-04-2002)“…Moenomycin has been highly selectively converted into amino derivative 3b. The primary amino group of this compound can be used to attach various fluorescent…”
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Moenomycin-Mediated Affinity Purification of Penicillin-Binding Protein 1b
Published in Chembiochem : a European journal of chemical biology (02-04-2002)“…The antibiotic moenomycin A inhibits the biosynthesis of peptidoglycan, the main structural polymer of the bacterial cell wall. The inhibition is based on a…”
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A Method for the Introduction of Reporter Groups into Moenomycin A, Based on Thiouronium Salt Chemistry
Published in European journal of organic chemistry (01-04-2002)“…p‐Alkoxy‐substituted cinnamylthiouronium salts 7, 13, 21a, and 21b reacted selectively with the 2‐acylamino‐1,3‐cyclopentanedione unit A of moenomycin A (1) to…”
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Some Selective Reactions of Moenomycin A
Published in Bioorganic & medicinal chemistry letters (04-09-2000)“…A number of new moenomycin A derivatives have been prepared. Their antibiotic properties highlight the very specific recognition of moenomycin A at the…”
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Synthesis of tools for raising antibodies against moenomycin epitopes and initial immunological studies
Published in Tetrahedron (16-09-2002)“…The moenomycins A and C 1 as well as penta-, di- and monosaccharide analogues have been conjugated to BSA and biotin, respectively. The moenomycin A–BSA…”
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Synthese von Neo‐Peptidoglycanen: eine überraschende Aktivität proteolytischer Enzyme
Published in Angewandte Chemie (02-08-2002)“…An jeder beliebigen Peptid‐Carboxygruppe ist eine Kohlenhydratanknüpfung möglich. Der Prozess basiert auf einer neuen hochselektiven, biokatalytischen…”
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