Search Results - "Buchheim, Katharina"

Dentate gyrus autonomous ictal activity in the status epilepticus rat model of epilepsy by Weissinger, Florian, Wawra, Matthias, Fidzinski, Pawel, Elsner, Mark, Meierkord, Hartmut, Holtkamp, Martin, Buchheim, Katharina

“…Graphical abstract…”
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Seizure spread through the life cycle: Optical imaging in combined brain slices from immature, adult, and senile rats in vitro by Weissinger, Florian, Buchheim, Katharina, Siegmund, Herbert, Meierkord, Hartmut

“…The semiology of epileptic seizures changes during the lifetime. Hence, it can be assumed that age-related changes in brain plasticity influence the patterns…”
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Processes and components participating in the generation of intrinsic optical signal changes in vitro by Buchheim, Katharina, Wessel, Ole, Siegmund, Herbert, Schuchmann, Sebastian, Meierkord, Hartmut

“…Imaging of intrinsic optical signals has become an important tool in the neurosciences. To better understand processes underlying changes in intrinsic optical…”
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Furosemide Terminates Limbic Status Epilepticus in Freely Moving Rats by Holtkamp, Martin, Matzen, Julia, Buchheim, Katharina, Walker, Matthew C., Meierkord, Hartmut

“…Purpose: To evaluate the anticonvulsant properties of furosemide and to determine sedative side effects compared with pentobarbital and diuretic side effects…”
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Optical Imaging Reveals Characteristic Seizure Onsets, Spread Patterns, and Propagation Velocities in Hippocampal–Entorhinal Cortex Slices of Juvenile Rats by Weissinger, Florian, Buchheim, Katharina, Siegmund, Herbert, Heinemann, Uwe, Meierkord, Hartmut

“…We have combined recordings with extracellular microelectrodes or ion-sensitive electrodes and imaging of intrinsic optical signal changes to study the…”
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Limbic Self‐sustaining Status Epilepticus in Rats Is Not Associated with Hyperthermia by Schmitt, Friedhelm C., Matzen, Julia, Buchheim, Katharina, Meierkord, Hartmut, Holtkamp, Martin

“…Purpose: To evaluate the impact of limbic status epilepticus on temperature. Methods: The perforant path in freely moving rats was stimulated electrically for…”
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Intrinsic Optical Imaging Reveals Regionally Different Manifestation of Spreading Depression in Hippocampal and Entorhinal Structures in Vitro by Buchheim, Katharina, Weissinger, Florian, Siegmund, Herbert, Holtkamp, Martin, Schuchmann, Sebastian, Meierkord, Hartmut

“…The spatiotemporal features of spreading depression (SD) were analyzed in vitro by using combined hippocampal–entorhinal cortex slices. SDs were induced by…”
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Circadian dentate gyrus excitability in a rat model of temporal lobe epilepsy by Matzen, Julia, Buchheim, Katharina, Holtkamp, Martin

“…In human mesial temporal lobe epilepsy (mTLE), seizure occurrence peaks in the late afternoon and early evening. This temporal binding of seizures has been…”
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Monitoring NAD(P)H autofluorescence to assess mitochondrial metabolic functions in rat hippocampal–entorhinal cortex slices by Schuchmann, Sebastian, Kovacs, Richard, Kann, Oliver, Heinemann, Uwe, Buchheim, Katharina

“…Changes in neuronal energy metabolism, mitochondrial functions and homeostasis of reactive oxygen species are often supposed to induce alterations in neuronal…”
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Comparison of Intrinsic Optical Signals Associated with Low Mg 2+ – and 4‐Aminopyridine–Induced Seizure‐Like Events Reveals Characteristic Features in Adult Rat Limbic System by Buchheim, Katharina, Schuchmann, Sebastian, Siegmund, Herbert, Weissinger, Florian, Heinemann, Uwe, Meierkord, Hartmut

“…Purpose : To analyze the intrinsic optical signal change associated with seizure‐like events in two frequently used in vitro models—the low‐Mg 2+ and the…”
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Diagnosis of psychogenic nonepileptic status epilepticus in the emergency setting by HOLTKAMP, Martin, OTHMAN, Jalal, BUCHHEIM, Katharina, MEIERKORD, Hartmut

“…Episodes of psychogenic nonepileptic status epilepticus (PNESE) characterized by pronounced generalized motor features were compared with those of refractory…”
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Increased extracellular K+ concentration reduces the efficacy of N-methyl-D-aspartate receptor antagonists to block spreading depression-like depolarizations and spreading ischemia by PETZOLD, Gabor C, WINDMÜLLER, Olaf, MEIERKORD, Hartmut, HEINEMANN, Uwe, DIRNAGL, Ulrich, DREIER, Jens P, HAACK, Stephan, MAJOR, Sebastian, BUCHHEIM, Katharina, MEGOW, Dirk, GABRIEL, Siegrun, LEHMANN, Thomas-Nicolas, DRENCKHAHN, Ristoph, PETERS, Oliver

“…Spreading depression (SD)-like depolarizations may augment neuronal damage in neurovascular disorders such as stroke and traumatic brain injury. Spreading…”
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Repetitive Spreading Depression-Like Events Result in Cell Damage in Juvenile Hippocampal Slice Cultures Maintained in Normoxia by Pomper, Jorn K, Haack, Stephan, Petzold, Gabor C, Buchheim, Katharina, Gabriel, Siegrun, Hoffmann, Ulrike, Heinemann, Uwe

“…1 Institut für Neurophysiologie and 2 Neurologische Klinik und Poliklinik, 3 Institut für Experimentelle Neurologie, Charité Universitätsmedizin Berlin,…”
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Oxygen consumption and mitochondrial membrane potential indicate developmental adaptation in energy metabolism of rat cortical neurons by Schuchmann, Sebastian, Buchheim, Katharina, Heinemann, Uwe, Hosten, Norbert, Buttgereit, Frank

“…Neuronal energy needs are mainly covered via mitochondrial oxidative phosphorylation. Even if the energy supply appears identical in immature and adult brain,…”
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Temperature regulation is compromised in experimental limbic status epilepticus by Holtkamp, Martin, Schmitt, Friedhelm C, Buchheim, Katharina, Meierkord, Hartmut

“…Abstract Temperature dysregulation is well known in generalized convulsive status epilepticus but so far has not been reported in non-convulsive forms. In…”
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Functional and morphological changes in the dentate gyrus after experimental status epilepticus by Matzen, Julia, Buchheim, Katharina, van Landeghem, Frank K.H, Meierkord, Hartmut, Holtkamp, Martin

“…Summary Status epilepticus may cause long-term functional and structural consequences possibly resulting in brain dysfunctions such as chronic epilepsy. In…”
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Decrease in haemoglobin oxygenation during absence seizures in adult humans by Buchheim, Katharina, Obrig, Hellmuth, v. Pannwitz, Wolfram, Müller, Anne, Heekeren, Hauke, Villringer, Arno, Meierkord, Hartmut

“…Near-infrared spectroscopy (NIRS) is a noninvasive method that allows the assessment of activation-induced cortical oxygenation changes in humans. It has been…”
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Increased extracellular potassium concentration reduces the efficacy of N-methyl-D-aspartate receptor antagonists to block spreading depression in human and rat brain slices by Petzold, Gabor C, Haack, Stephan, Megow, Dirk, Buchheim, Katharina, Heinemann, Uwe, Dirnagl, Ulrich, Dreier, Jens P

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A "malignant" variant of status epilepticus by Holtkamp, Martin, Othman, Jalal, Buchheim, Katharina, Masuhr, Florian, Schielke, Eva, Meierkord, Hartmut

“…Status epilepticus (SE) frequently does not respond to common first-line anticonvulsants. In a substantial portion of patients, administration of…”
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Increased Extracellular K super(+) Concentration Reduces the Efficacy of N-methyl-D-aspartate Receptor Antagonists to Block Spreading Depression-Like Depolarizations and Spreading Ischemia by Petzold, Gabor C, Windmueller, Olaf, Haack, Stephan, Major, Sebastian, Buchheim, Katharina, Megow, Dirk, Gabriel, Siegrun, Lehmann, Thomas-Nicolas, Drenckhahn, Christoph, Peters, Oliver, Meierkord, Hartmut, Heinemann, Uwe, Dirnagl, Ulrich, Dreier, Jens P

“…BACKGROUND: and Purpose- Spreading depression (SD)-like depolarizations may augment neuronal damage in neurovascular disorders such as stroke and traumatic…”
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