Search Results - "Buchanan, Gordon F"

Stopping runaway seizures with a chill pill by Buchanan, Gordon F

“…The neuropeptide neurotensin can reduce status epilepticus and its associated consequences through induction of therapeutic hypothermia when bound to a…”
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Central serotonin neurons are required for arousal to CO2 by Buchanan, Gordon F, Richerson, George B

“…There is a long-standing controversy about the role of serotonin in sleep/wake control, with competing theories that it either promotes sleep or causes…”
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Serotonin neurones have anti‐convulsant effects and reduce seizure‐induced mortality by Buchanan, Gordon F., Murray, Nicholas M., Hajek, Michael A., Richerson, George B.

“…Key points Sudden unexpected death in epilepsy is the leading cause of death in patients with refractory epilepsy. Respiratory and cardiac impairment induced…”
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Under New Management: Transplanted GABAergic Progenitors Control Adult Neurogenesis by Buchanan, Gordon F.

“…Hippocampal Transplants of Fetal GABAergic Progenitors Regulate Adult Neurogenesis in Mice With Temporal Lobe Epilepsy Arshad MN, Oppenheimer S, Jeong J,…”
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Convulsive seizures from experimental focal cortical dysplasia occur independently of cell misplacement by Hsieh, Lawrence S., Wen, John H., Claycomb, Kumiko, Huang, Yuegao, Harrsch, Felicia A., Naegele, Janice R., Hyder, Fahmeed, Buchanan, Gordon F., Bordey, Angelique

“…Focal cortical dysplasia (FCD), a local malformation of cortical development, is the most common cause of pharmacoresistant epilepsy associated with life-long…”
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Chronobiology of epilepsy and sudden unexpected death in epilepsy by Kreitlow, Benjamin L., Li, William, Buchanan, Gordon F.

“…Epilepsy is a neurological disease characterized by spontaneous, unprovoked seizures. Various insults render the brain hyperexcitable and susceptible to…”
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Dead in the Night: Sleep-Wake and Time-Of-Day Influences on Sudden Unexpected Death in Epilepsy by Purnell, Benton S, Thijs, Roland D, Buchanan, Gordon F

“…Sudden unexpected death in epilepsy (SUDEP) is the leading cause of epilepsy-related death in patients with refractory epilepsy. Convergent lines of evidence…”
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Insomnia Caused by Serotonin Depletion is Due to Hypothermia by Murray, Nicholas M, Buchanan, Gordon F, Richerson, George B

“…Serotonin (5-hydroxytryptamine, 5-HT) neurons are now thought to promote wakefulness. Early experiments using the tryptophan hydroxylase inhibitor…”
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5-HT2A receptor activation is necessary for CO2-induced arousal by Buchanan, Gordon F, Smith, Haleigh R, MacAskill, Amanda, Richerson, George B

“…Hypercapnia-induced arousal from sleep is an important protective mechanism pertinent to a number of diseases. Most notably among these are the sudden infant…”
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Dorsal Raphe Serotonin Neurons Mediate CO2-Induced Arousal from Sleep by Smith, Haleigh R, Leibold, Nicole K, Rappoport, Daniel A, Ginapp, Callie M, Purnell, Benton S, Bode, Nicole M, Alberico, Stephanie L, Kim, Young-Cho, Audero, Enrica, Gross, Cornelius T, Buchanan, Gordon F

“…Arousal from sleep in response to CO 2 is a critical protective phenomenon. Dysregulation of CO 2 -induced arousal contributes to morbidity and mortality from…”
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The role of sleep state and time of day in modulating breathing in epilepsy: implications for sudden unexpected death in epilepsy by Joyal, Katelyn G., Kreitlow, Benjamin L., Buchanan, Gordon F.

“…Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death among patients with refractory epilepsy. While the exact etiology of SUDEP is…”
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Impaired CO2-Induced Arousal in SIDS and SUDEP by Buchanan, Gordon F.

“…Premature, sudden death is devastating. Certain patient populations are at greater risk to succumb to sudden death. For instance, infants under 1year of age…”
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Impaired CO 2 -Induced Arousal in SIDS and SUDEP by Buchanan, Gordon F

“…Premature, sudden death is devastating. Certain patient populations are at greater risk to succumb to sudden death. For instance, infants under 1year of age…”
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Optogenetic stimulation of cholinergic brainstem neurons during focal limbic seizures: Effects on cortical physiology by Furman, Moran, Zhan, Qiong, McCafferty, Cian, Lerner, Benjamin A., Motelow, Joshua E., Meng, Jin, Ma, Chanthia, Buchanan, Gordon F., Witten, Ilana B., Deisseroth, Karl, Cardin, Jessica A., Blumenfeld, Hal

“…Summary Focal temporal lobe seizures often cause impaired cortical function and loss of consciousness. Recent work suggests that the mechanism for depressed…”
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Ca2+/cAMP Response Element-binding Protein (CREB)-dependent Activation of Per1 Is Required for Light-induced Signaling in the Suprachiasmatic Nucleus Circadian Clock by Tischkau, Shelley A., Mitchell, Jennifer W., Tyan, Sheue-Houy, Buchanan, Gordon F., Gillette, Martha U.

“…Light is a prominent stimulus that synchronizes endogenous circadian rhythmicity to environmental light/dark cycles. Nocturnal light elevates mRNA of the…”
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Who's Down With UDP?-Not Epilepsy; Purinergic Microglial Ca2+ Signaling Mediates Epileptogenesis by Buchanan, Gordon F

“…Purinergic mechanisms mediate microglial Ca 2 + signaling in epileptogenesis Umpierre, AD, Li, B, Katayoun, A, Simon, WL, Zhao, S, Xie, M, Thyen, G, Hur, B,…”
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Assessment of Cellular End of Life Management in Acute Brain Injury: Clearing Dying Cells After Injury by Buchanan, Gordon F.

“…A Dynamic Balance Between Neuronal Death and Clearance in an In Vitro Model of Acute Brain Injury Balena T, Lillis K, Rahmati N, Bahari F, Dzhala V,…”
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Leigh has no Brakes: Impaired Inhibition in a Mouse Model of Leigh Syndrome Leads to Enhanced Seizure Sensitivity by Buchanan, Gordon F.

“…Elevated Susceptibility to Exogenous Seizure Triggers and Impaired Interneuron Excitability in a Mouse Model of Leigh Syndrome Epilepsy Manning A, Han V,…”
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Revoking the Seize Order: Preventing Spontaneous Seizures With AAV in a CLN2 Mouse Model by Buchanan, Gordon F.

“…Gene Therapy Ameliorates Spontaneous Seizures Associated With Cortical Neuron Loss in a Cln2R207X Mouse Model Takahashi K, Eultgen EM, Wang S, Rensing NR,…”
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Slow Down and Seize: Seizures Triggered by Slow Wave Oscillations in a GABAergic Model of Dravet Syndrome by Buchanan, Gordon F.

“…Sleep Slow-Wave Oscillations Trigger Seizures in a Genetic Epilepsy Model of Dravet Syndrome Catron MA, Howe RK, Besing GK, St John EK, Potesta CV, Gallagher…”
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