Search Results - "Buchanan, G F"
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CO2 exposure as translational cross-species experimental model for panic
Published in Translational psychiatry (06-09-2016)“…The current diagnostic criteria of the Diagnostic and Statistical Manual of Mental Disorders are being challenged by the heterogeneity and the symptom overlap…”
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Localization and behaviors in null mice suggest that ASIC1 and ASIC2 modulate responses to aversive stimuli
Published in Genes, brain and behavior (01-02-2014)“…Acid‐sensing ion channels (ASICs) generate H+‐gated Na+ currents that contribute to neuronal function and animal behavior. Like ASIC1, ASIC2 subunits are…”
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Differential cAMP Gating of Glutamatergic Signaling Regulates Long-Term State Changes in the Suprachiasmatic Circadian Clock
Published in The Journal of neuroscience (15-10-2000)“…We investigated a role for cAMP/protein kinase A (PKA) in light/glutamate (GLU)-stimulated state changes of the mammalian circadian clock in the…”
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The brain acid-base homeostasis and serotonin: A perspective on the use of carbon dioxide as human and rodent experimental model of panic
Published in Progress in neurobiology (01-06-2015)“…Panic attacks (PAs), the core feature of panic disorder, represent a common phenomenon in the general adult population and are associated with a considerable…”
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Growth-dependent accumulation of monoalkylglycerol in Madin-Darby canine kidney cells. Evidence for a role in the regulation of protein kinase C
Published in The Journal of biological chemistry (12-05-1995)“…1-O-Alkyl-sn-glycerol (alkylglycerol) forms the backbone of complex ether-linked glycerolipids, including biologically active lipids such as…”
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Pituitary Adenylyl Cyclase-Activating Peptide: A Pivotal Modulator of Glutamatergic Regulation of the Suprachiasmatic Circadian Clock
Published in Proceedings of the National Academy of Sciences - PNAS (09-11-1999)“…The circadian clock in the suprachiasmatic nucleus (SCN) of the hypothalamus organizes behavioral rhythms, such as the sleep-wake cycle, on a near 24-h time…”
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7
Ca2+/Calmodulin-dependent Protein Kinase II Regulates Tiam1 by Reversible Protein Phosphorylation
Published in The Journal of biological chemistry (30-04-1999)“…A number of guanine nucleotide exchange factors have been identified that activate Rho family GTPases, by promoting the binding of GTP to these proteins. We…”
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A neuronal ryanodine receptor mediates light-induced phase delays of the circadian clock
Published in Nature (London) (23-07-1998)“…Circadian clocks are complex biochemical systems that cycle with a period of approximately 24 hours. They integrate temporal information regarding phasing of…”
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Translocation of the Rac1 Guanine Nucleotide Exchange Factor Tiam1 Induced by Platelet-derived Growth Factor and Lysophosphatidic Acid
Published in The Journal of biological chemistry (31-03-2000)“…Several guanine nucleotide exchange factors for the Rho family of GTPases that induce activation by exchanging GDP for GTP have been identified. One of these…”
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An animal cell mutant with a deficiency in acyl/alkyl-dihydroxyacetone-phosphate reductase activity. Effects on the biosynthesis of ether-linked and diacyl glycerolipids
Published in The Journal of biological chemistry (19-09-1997)“…In the accompanying paper (James, P. F., and Zoeller, R. A. (1997) J. Biol. Chem. 272, 23532-23539), we reported the isolation of a series of mutants from the…”
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11
Connecting COX-2 and Wnt in cancer
Published in Cancer cell (2006)“…Both the cyclooxygenase-2 (COX-2) and Wnt signaling cascades are active in the majority of colorectal cancers. Nevertheless, a direct link between these two…”
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Role of β-Arrestin 1 in the Metastatic Progression of Colorectal Cancer
Published in Proceedings of the National Academy of Sciences - PNAS (31-01-2006)“…G protein-coupled receptor ligand-dependent transactivation of growth factor receptors has been implicated in human cancer cell proliferation, migration, and…”
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15-Hydroxyprostaglandin Dehydrogenase Is Down-regulated in Colorectal Cancer
Published in The Journal of biological chemistry (04-02-2005)“…Prostaglandin E2 (PGE2) can stimulate tumor progression by modulating several proneoplastic pathways, including proliferation, angiogenesis, cell migration,…”
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Ca2+/cAMP Response Element-binding Protein (CREB)-dependent Activation of Per1 Is Required for Light-induced Signaling in the Suprachiasmatic Nucleus Circadian Clock
Published in The Journal of biological chemistry (10-01-2003)“…Light is a prominent stimulus that synchronizes endogenous circadian rhythmicity to environmental light/dark cycles. Nocturnal light elevates mRNA of the…”
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Prostaglandin E sub(2) Regulates Cell Migration via the Intracellular Activation of the Epidermal Growth Factor Receptor
Published in The Journal of biological chemistry (12-09-2003)“…Over the past decade cyclooxygenase-2-derived prostaglandins have been implicated in the development and progression of many types of cancer. Recently our…”
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A neuronal ryanodine receptor mediates light-induced phase delays of the circadian clock
Published in Nature (London) (01-07-1998)Get full text
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17
Ca super(2+)/cAMP Response Element-binding Protein (CREB)-dependent Activation of Per1 Is Required for Light-induced Signaling in the Suprachiasmatic Nucleus Circadian Clock
Published in The Journal of biological chemistry (10-01-2003)“…Light is a prominent stimulus that synchronizes endogenous circadian rhythmicity to environmental light/dark cycles. Nocturnal light elevates mRNA of the…”
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18
New light on an old paradox: site-dependent effects of carbachol on circadian rhythms
Published in Experimental neurology (01-06-2005)“…Acetylcholine (ACh) was the first neurotransmitter identified as a regulator of mammalian circadian rhythms. When injected in vivo, cholinergics induced…”
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Role of the M sub(1) receptor in regulating circadian rhythms
Published in Life sciences (1973) (27-04-2001)“…Cholinergic stimuli are potent regulators of the circadian clock in the hypothalamic suprachiasmatic nucleus (SCN). Using a brain slice model, we have found…”
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Oncogenic Potential of MEK1 in Rat Intestinal Epithelial Cells Is Mediated via Cyclooxygenase-2
Published in Gastroenterology (New York, N.Y. 1943) (01-08-2005)“…Background & Aims: The mitogen-activated protein kinase/extracellular signal-regulated protein kinase kinase (MEK) pathway plays an important role in the…”
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