Search Results - "Buchanan, D"

The prognostic impact of consensus molecular subtypes (CMS) and its predictive effects for bevacizumab benefit in metastatic colorectal cancer: molecular analysis of the AGITG MAX clinical trial by Mooi, J.K., Wirapati, P., Asher, R., Lee, C.K., Savas, P., Price, T.J., Townsend, A., Hardingham, J., Buchanan, D., Williams, D., Tejpar, S., Mariadason, J.M., Tebbutt, N.C.

“…The consensus molecular subtypes (CMS) is a transcriptome-based classification of colorectal cancer (CRC) initially described in early-stage cohorts, but the…”
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Cardiovascular risk of electronic cigarettes: a review of preclinical and clinical studies by Buchanan, Nicholas D, Grimmer, Jacob A, Tanwar, Vineeta, Schwieterman, Neill, Mohler, Peter J, Wold, Loren E

“…Abstract Cigarette smoking is the most preventable risk factor related to cardiovascular morbidity and mortality. Tobacco usage has declined in recent years;…”
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Niche filling slows the diversification of Himalayan songbirds by Price, Trevor D., Hooper, Daniel M., Buchanan, Caitlyn D., Johansson, Ulf S., Tietze, D. Thomas, Alström, Per, Olsson, Urban, Ghosh-Harihar, Mousumi, Ishtiaq, Farah, Gupta, Sandeep K., Martens, Jochen, Harr, Bettina, Singh, Pratap, Mohan, Dhananjai

“…In Himalayan songbirds, the speciation rate is ultimately set by ecological competition, rather than by the rate of acquisition of reproductive isolation. New…”
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KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers by Phipps, A I, Buchanan, D D, Makar, K W, Win, A K, Baron, J A, Lindor, N M, Potter, J D, Newcomb, P A

“…Background: Mutations in the Kirsten Ras ( KRAS ) oncogene are common in colorectal cancer (CRC). The role of KRAS- mutation status as a prognostic factor,…”
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Association Between Molecular Subtypes of Colorectal Cancer and Patient Survival by Phipps, Amanda I, Limburg, Paul J, Baron, John A, Burnett-Hartman, Andrea N, Weisenberger, Daniel J, Laird, Peter W, Sinicrope, Frank A, Rosty, Christophe, Buchanan, Daniel D, Potter, John D, Newcomb, Polly A

“…Background and Aims Colorectal cancer (CRC) is a heterogeneous disease that can develop via several pathways. Different CRC subtypes, identified based on tumor…”
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The Association Between Adverse Childhood Experiences and Risk of Cancer in Adulthood: A Systematic Review of the Literature by Holman, Dawn M, Ports, Katie A, Buchanan, Natasha D, Hawkins, Nikki A, Merrick, Melissa T, Metzler, Marilyn, Trivers, Katrina F

“…Adverse childhood experiences (ACEs) can affect health and well-being across the life course. This systematic review summarizes the literature on associations…”
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Prevalence and Penetrance of Major Genes and Polygenes for Colorectal Cancer by Win, Aung Ko, Jenkins, Mark A, Dowty, James G, Antoniou, Antonis C, Lee, Andrew, Giles, Graham G, Buchanan, Daniel D, Clendenning, Mark, Rosty, Christophe, Ahnen, Dennis J, Thibodeau, Stephen N, Casey, Graham, Gallinger, Steven, Le Marchand, Loïc, Haile, Robert W, Potter, John D, Zheng, Yingye, Lindor, Noralane M, Newcomb, Polly A, Hopper, John L, MacInnis, Robert J

“…Although high-risk mutations in identified major susceptibility genes (DNA mismatch repair genes and ) account for some familial aggregation of colorectal…”
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Is the Mitochondrion a Good Malaria Drug Target? by Goodman, Christopher D, Buchanan, Hayley D, McFadden, Geoffrey I

“…Rapid emergence of resistance to atovaquone, which targets electron transport in the malaria parasite mitochondrion, relegated its use to prophylaxis and even…”
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Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study by Dienstmann, R., Mason, M.J., Sinicrope, F.A., Phipps, A.I., Tejpar, S., Nesbakken, A., Danielsen, S.A., Sveen, A., Buchanan, D.D., Clendenning, M., Rosty, C., Bot, B., Alberts, S.R., Milburn Jessup, J., Lothe, R.A., Delorenzi, M., Newcomb, P.A., Sargent, D., Guinney, J.

“…TNM staging alone does not accurately predict outcome in colon cancer (CC) patients who may be eligible for adjuvant chemotherapy. It is unknown to what extent…”
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DNA methylation‐based biological aging and cancer risk and survival: Pooled analysis of seven prospective studies by Dugué, Pierre‐Antoine, Bassett, Julie K., Joo, JiHoon E., Jung, Chol‐Hee, Ming Wong, Ee, Moreno‐Betancur, Margarita, Schmidt, Daniel, Makalic, Enes, Li, Shuai, Severi, Gianluca, Hodge, Allison M., Buchanan, Daniel D., English, Dallas R., Hopper, John L., Southey, Melissa C., Giles, Graham G., Milne, Roger L.

“…The association between aging and cancer is complex. Recent studies have developed measures of biological aging based on DNA methylation and called them “age…”
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Risks of Primary Extracolonic Cancers Following Colorectal Cancer in Lynch Syndrome by KOWIN, Aung, LINDOR, Noralane M, LEGGETT, Barbara, TUCKER, Katherine M, GILES, Graham G, BUCHANAN, Daniel D, CLENDENNING, Mark, ROSTY, Christophe, ARNOLD, Julie, JOAN LEVINE, A, HAILE, Robert W, GALLINGER, Steven, PYOUNG, Joanne, LE MARCHAND, Loïc, NEWCOMB, Polly A, HOPPER, John L, JENKINS, Mark A, MACRAE, Finlay A, PYOUNG, Graeme, WILLIAMSON, Elizabeth, PARRY, Susan, GOLDBLATT, Jack, LIPTON, Lara, WINSHIP, Ingrid

“…Lynch syndrome is a highly penetrant cancer predisposition syndrome caused by germline mutations in DNA mismatch repair (MMR) genes. We estimated the risks of…”
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Oncomicrobial Community Profiling Identifies Clinicomolecular and Prognostic Subtypes of Colorectal Cancer by Mouradov, Dmitri, Greenfield, Paul, Li, Shan, In, Eun-Jung, Storey, Claire, Sakthianandeswaren, Anuratha, Georgeson, Peter, Buchanan, Daniel D., Ward, Robyn L., Hawkins, Nicholas J., Skinner, Iain, Jones, Ian T., Gibbs, Peter, Ma, Chenkai, Liew, Yi Jin, Fung, Kim Y.C., Sieber, Oliver M.

“…Dysbiosis of gut microbiota is linked to the development of colorectal cancer (CRC). However, microbiota-based stratification of CRC tissue and how this…”
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Identification and Quantification of Polymorphism in the Pharmaceutical Compound Diclofenac Acid by Terahertz Spectroscopy and Solid-State Density Functional Theory by King, Matthew D, Buchanan, William D, Korter, Timothy M

“…Polymorph detection and quantification in crystalline materials is a principle interest of the pharmaceutical industry. Terahertz (THz) spectroscopy can be…”
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Sleep disturbances in irritable bowel syndrome: a systematic review by Tu, Q., Heitkemper, M. M., Jarrett, M. E., Buchanan, D. T.

“…Background Sleep disturbances are well‐documented among persons with irritable bowel syndrome (IBS). Difficulty in falling asleep, shorter sleep time, frequent…”
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Potential impact of family history–based screening guidelines on the detection of early‐onset colorectal cancer by Gupta, Samir, Bharti, Balambal, Ahnen, Dennis J., Buchanan, Daniel D., Cheng, Iona C., Cotterchio, Michelle, Figueiredo, Jane C., Gallinger, Steven J., Haile, Robert W., Jenkins, Mark A., Lindor, Noralane M., Macrae, Finlay A., Le Marchand, Loïc, Newcomb, Polly A., Thibodeau, Stephen N., Win, Aung Ko, Martinez, Maria Elena

“…Background Initiating screening at an earlier age based on cancer family history is one of the primary recommended strategies for the prevention and detection…”
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Root and canal configurations of mandibular first molars in a South African subpopulation by Tredoux, Sheree, Warren, Nichola, Buchanan, Glynn D.

“…Purpose: This study investigated root number and canal configurations, including morphological variations, of mandibular first molars in a subpopulation of…”
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Colorectal and Other Cancer Risks for Carriers and Noncarriers From Families With a DNA Mismatch Repair Gene Mutation: A Prospective Cohort Study by AUNG KO WIN, YOUNG, Joanne P, MACRAE, Finlay A, GOLDBLATT, Jack, SOUTHEY, Melissa C, ARNOLD, Julie, THIBODEAU, Stephen N, GUNAWARDENA, Shanaka R, BAPAT, Bharati, BARON, John A, CASEY, Graham, GALLINGER, Steven, LINDOR, Noralane M, MARCHAND, Loïc Le, NEWCOMB, Polly A, HAILE, Robert W, HOPPER, John L, JENKINS, Mark A, TUCKER, Katherine M, AHNEN, Dennis J, YOUNG, Graeme P, BUCHANAN, Daniel D, CLENDENNING, Mark, GILES, Graham G, WINSHIP, Ingrid

“…To determine whether cancer risks for carriers and noncarriers from families with a mismatch repair (MMR) gene mutation are increased above the risks of the…”
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Update on Hereditary Colorectal Cancer: Improving the Clinical Utility of Multigene Panel Testing by Lorans, Marie, Dow, Eryn, Macrae, Finlay A., Winship, Ingrid M., Buchanan, Daniel D.

“…Colorectal cancer (CRC), one of the most common cancers, is a major public health issue globally, especially in Westernized countries. Up to 35% of CRCs are…”
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Tumor Mismatch Repair Immunohistochemistry and DNA MLH1 Methylation Testing of Patients With Endometrial Cancer Diagnosed at Age Younger Than 60 Years Optimizes Triage for Population-Level Germline Mismatch Repair Gene Mutation Testing by BUCHANAN, Daniel D, TAN, Yen Y, WALTERS, Rhiannon J, PEARSON, Sally-Ann, CUMMINGS, Margaret, OEHLER, Martin K, BLOMFIELD, Penelope B, QUINN, Michael A, KIRK, Judy A, STEWART, Colin J, OBERMAIR, Andreas, YOUNG, Joanne P, WALSH, Michael D, WEBB, Penelope M, SPURDLE, Amanda B, CLENDENNING, Mark, METCALF, Alexander M, FERGUSON, Kaltin, ARNOLD, Sven T, THOMPSON, Bryony A, LOSE, Felicity A, PARSONS, Michael T

“…Clinicopathologic data from a population-based endometrial cancer cohort, unselected for age or family history, were analyzed to determine the optimal scheme…”
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Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study by Morales Berstein, Fernanda, McCartney, Daniel L, Lu, Ake T, Tsilidis, Konstantinos K, Bouras, Emmanouil, Haycock, Philip, Burrows, Kimberley, Phipps, Amanda I, Buchanan, Daniel D, Cheng, Iona, Martin, Richard M, Davey Smith, George, Relton, Caroline L, Horvath, Steve, Marioni, Riccardo E, Richardson, Tom G, Richmond, Rebecca C

“…Epigenetic clocks have been associated with cancer risk in several observational studies. Nevertheless, it is unclear whether they play a causal role in cancer…”
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