Search Results - "Buchacher, Tanja"

M2 Polarization of Human Macrophages Favors Survival of the Intracellular Pathogen Chlamydia pneumoniae by Buchacher, Tanja, Ohradanova-Repic, Anna, Stockinger, Hannes, Fischer, Michael B, Weber, Viktoria

“…Intracellular pathogens have developed various strategies to escape immunity to enable their survival in host cells, and many bacterial pathogens…”
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Bacillus cereus extracellular vesicles act as shuttles for biologically active multicomponent enterotoxins by Buchacher, Tanja, Digruber, Astrid, Kranzler, Markus, Del Favero, Giorgia, Ehling-Schulz, Monika

“…Extracellular vesicles (EVs) from Gram-positive bacteria have gained considerable importance as a novel transport system of virulence factors in host-pathogen…”
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Correction: Bacillus cereus extracellular vesicles act as shuttles for biologically active multicomponent enterotoxins by Buchacher, Tanja, Digruber, Astrid, Kranzler, Markus, Del Favero, Giorgia, Ehling-Schulz, Monika

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PIM kinases regulate early human Th17 cell differentiation by Buchacher, Tanja, Shetty, Ankitha, Koskela, Saara A., Smolander, Johannes, Kaukonen, Riina, Sousa, António G.G., Junttila, Sini, Laiho, Asta, Rundquist, Olof, Lönnberg, Tapio, Marson, Alexander, Rasool, Omid, Elo, Laura L., Lahesmaa, Riitta

“…The serine/threonine-specific Moloney murine leukemia virus (PIM) kinase family (i.e., PIM1, PIM2, and PIM3) has been extensively studied in tumorigenesis. PIM…”
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The secretome of apoptotic human peripheral blood mononuclear cells attenuates secondary damage following spinal cord injury in rats by Haider, Thomas, Höftberger, Romana, Rüger, Beate, Mildner, Michael, Blumer, Roland, Mitterbauer, Andreas, Buchacher, Tanja, Sherif, Camillo, Altmann, Patrick, Redl, Heinz, Gabriel, Christian, Gyöngyösi, Mariann, Fischer, Michael B., Lubec, Gert, Ankersmit, Hendrik Jan

“…After spinal cord injury (SCI), secondary damage caused by oxidative stress, inflammation, and ischemia leads to neurological deterioration. In recent years,…”
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Interactome Networks of FOSL1 and FOSL2 in Human Th17 Cells by Shetty, Ankitha, Bhosale, Santosh D, Tripathi, Subhash Kumar, Buchacher, Tanja, Biradar, Rahul, Rasool, Omid, Moulder, Robert, Galande, Sanjeev, Lahesmaa, Riitta

“…Dysregulated function of Th17 cells has implications in immunodeficiencies and autoimmune disorders. Th17 cell differentiation is orchestrated by a complex…”
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Vascular Morphogenesis in the Context of Inflammation: Self-Organization in a Fibrin-Based 3D Culture System by Rüger, Beate M, Buchacher, Tanja, Giurea, Alexander, Kubista, Bernd, Fischer, Michael B, Breuss, Johannes M

“…New vessel formation requires a continuous and tightly regulated interplay between endothelial cells with cells of the perivascular microenvironment supported…”
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De novo Vessel Formation Through Cross-Talk of Blood-Derived Cells and Mesenchymal Stromal Cells in the Absence of Pre-existing Vascular Structures by Rüger, Beate M, Buchacher, Tanja, Dauber, Eva-Maria, Pasztorek, Markus, Uhrin, Pavel, Fischer, Michael B, Breuss, Johannes M, Leitner, Gerda C

“…The generation of functional blood vessels remains a key challenge for regenerative medicine. Optimized culture set-ups mimicking the perivascular niche…”
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Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells by Buchacher, Tanja, Honkimaa, Anni, Välikangas, Tommi, Lietzén, Niina, Hirvonen, M. Karoliina, Laiho, Jutta E., Sioofy-Khojine, Amir-Babak, Eskelinen, Eeva-Liisa, Hyöty, Heikki, Elo, Laura L., Lahesmaa, Riitta

“…Enteroviruses, particularly the group B coxsackieviruses (CVBs), have been associated with the development of type 1 diabetes. Several CVB serotypes establish…”
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Coxsackievirus B Persistence Modifies the Proteome and the Secretome of Pancreatic Ductal Cells by Lietzén, Niina, Hirvonen, Karoliina, Honkimaa, Anni, Buchacher, Tanja, Laiho, Jutta E., Oikarinen, Sami, Mazur, Magdalena A., Flodström-Tullberg, Malin, Dufour, Eric, Sioofy-Khojine, Amir-Babak, Hyöty, Heikki, Lahesmaa, Riitta

“…The group B Coxsackieviruses (CVB), belonging to the Enterovirus genus, can establish persistent infections in human cells. These persistent infections have…”
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Assessing the toxic potential of enteropathogenic Bacillus cereus by Jessberger, Nadja, Kranzler, Markus, Da Riol, Claudia, Schwenk, Valerie, Buchacher, Tanja, Dietrich, Richard, Ehling-Schulz, Monika, Märtlbauer, Erwin

“…The diarrheal type of food poisoning caused by enteropathogenic Bacillus cereus has been linked to various exotoxins. Best described are the non-hemolytic…”
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Phenotypic profiling of human induced regulatory T cells at early differentiation: insights into distinct immunosuppressive potential by Kattelus, Roosa, Starskaia, Inna, Lindén, Markus, Batkulwar, Kedar, Pietilä, Sami, Moulder, Robert, Marson, Alexander, Rasool, Omid, Suomi, Tomi, Elo, Laura L., Lahesmaa, Riitta, Buchacher, Tanja

“…Regulatory T cells (Tregs) play a key role in suppressing systemic effector immune responses, thereby preventing autoimmune diseases but also potentially…”
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A systematic comparison of FOSL1, FOSL2 and BATF-mediated transcriptional regulation during early human Th17 differentiation by Shetty, Ankitha, Tripathi, Subhash Kumar, Junttila, Sini, Buchacher, Tanja, Biradar, Rahul, Bhosale, Santosh D, Envall, Tapio, Laiho, Asta, Moulder, Robert, Rasool, Omid, Galande, Sanjeev, Elo, Laura L, Lahesmaa, Riitta

“…Th17 cells are essential for protection against extracellular pathogens, but their aberrant activity can cause autoimmunity. Molecular mechanisms that dictate…”
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Long noncoding RNA LIRIL2R modulates FOXP3 levels and suppressive function of human CD4 + regulatory T cells by regulating IL2RA by Andrabi, Syed Bilal Ahmad, Kalim, Ubaid Ullah, Palani, Senthil, Khan, Mohd Moin, Khan, Meraj Hasan, Fagersund, Jimmy, Orpana, Julius, Paulin, Niklas, Batkulwar, Kedar, Junttila, Sini, Buchacher, Tanja, Grönroos, Toni, Toikka, Lea, Ammunet, Tea, Sen, Partho, Orešič, Matej, Kumpulainen, Venla, Tuomisto, Johanna E E, Sinha, Rahul, Marson, Alexander, Rasool, Omid, Elo, Laura L, Lahesmaa, Riitta

“…Regulatory T cells (Tregs) are central in controlling immune responses, and dysregulation of their function can lead to autoimmune disorders or cancer. Despite…”
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HIC1 interacts with FOXP3 multi protein complex: Novel pleiotropic mechanisms to regulate human regulatory T cell differentiation and function by Andrabi, Syed Bilal Ahmad, Batkulwar, Kedar, Bhosale, Santosh D., Moulder, Robert, Khan, Meraj Hasan, Buchacher, Tanja, Khan, Mohd Moin, Arnkil, Ilona, Rasool, Omid, Marson, Alexander, Kalim, Ubaid Ullah, Lahesmaa, Riitta

“…Transcriptional repressor, hypermethylated in cancer 1 (HIC1) participates in a range of important biological processes, such as tumor repression, immune…”
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Quantitative analysis of human CD4+T-cell differentiation reveals subset-specific regulation of glycosphingolipid pathways by Sen, Partho, Andrabi, Syed Bilal Ahmad, Buchacher, Tanja, Khan, Mohd Moin, Ullah, Ubaid, Lindeman, Tuomas Mikael, Alves, Marina Amaral, Hinkkanen, Victoria, Kemppainen, Esko, Dickens, Alex M., Rasool, Omid, Hyötyläinen, Tuulia, Lahesmaa, Riitta, Oresic, Matej

“…T‐cells are sentinels of adaptive immune responses. T‐cell activation, proliferation and differentiation involves metabolic reprogramming involving the…”
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Quantitative genome-scale metabolic modeling of human CD4+ T cell differentiation reveals subset-specific regulation of glycosphingolipid pathways by Sen, Partho, Andrabi, Syed Bilal Ahmad, Buchacher, Tanja, Khan, Mohd Moin, Kalim, Ubaid Ullah, Lindeman, Tuomas Mikael, Alves, Marina Amaral, Hinkkanen, Victoria, Kemppainen, Esko, Dickens, Alex M., Rasool, Omid, Hyötyläinen, Tuulia, Lahesmaa, Riitta, Orešič, Matej

“…T cell activation, proliferation, and differentiation involve metabolic reprogramming resulting from the interplay of genes, proteins, and metabolites. Here,…”
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Human blood monocytes support persistence, but not replication of the intracellular pathogen C. pneumoniae by Buchacher, Tanja, Wiesinger-Mayr, Herbert, Vierlinger, Klemens, Rüger, Beate M, Stanek, Gerold, Fischer, Michael B, Weber, Viktoria

“…Intracellular pathogens have devised various mechanisms to subvert the host immune response in order to survive and replicate in host cells. Here, we studied…”
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Adsorptive modulation of inflammatory mediators dampens endothelial cell activation by Schildberger, Anita, Buchacher, Tanja, Weber, Viktoria, Falkenhagen, Dieter

“…In this study, the effect of specific or selective adsorption of inflammatory mediators on endothelial activation was assessed. Conditioned medium was obtained…”
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