Search Results - "Buch, T"
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Aberrant splicing of the tumor suppressor CYLD promotes the development of chronic lymphocytic leukemia via sustained NF-κB signaling
Published in Leukemia (01-01-2018)“…The pathogenesis of chronic lymphocytic leukemia (CLL) has been linked to constitutive NF-κB activation but the underlying mechanisms are poorly understood…”
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Is BAC Transgenesis Obsolete? State of the Art in the Era of Designer Nucleases
Published in Journal of biomedicine & biotechnology (01-01-2012)“…DNA constructs based on bacterial artificial chromosomes (BACs) are frequently used to generate transgenic animals as they reduce the influence of position…”
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420 Analysis of genomic alterations in Ewing sarcoma (German cohort) reveals cooperating mutations and novel therapy targets
Published in European journal of cancer (1990) (01-11-2014)Get full text
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MHC class II expression through a hitherto unknown pathway supports T helper cell-dependent immune responses: implications for MHC class II deficiency
Published in Blood (15-02-2006)“…MHC class II (MHCII) deficiency or bare lymphocyte syndrome (BLS) is a severe immunodeficiency characterized by deficient T helper (Th)-cell-dependent…”
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What Makes Cities Attractive? The Determinants of Urban Labour Migration in Germany
Published in Urban studies (Edinburgh, Scotland) (01-07-2014)“…Striking disparities characterise the population growth of cities in industrialised countries. Some cities suffer from ongoing population decline, whereas…”
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Epitope mapping and reactivity of autoantibodies to the E2 component of 2‐oxoglutarate dehydrogenase complex in primary biliary cirrhosis using recombinant 2‐oxoglutarate dehydrogenase complex
Published in Hepatology (Baltimore, Md.) (01-03-1996)“…Five different target mitochondrial autoantigens recognized by sera from patients with primary biliary cirrhosis (PBC) have been identified as subunits of the…”
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Socioeconomic status and trends in utilization of catheter ablation in patients hospitalized with atrial fibrillation in united states
Published in European heart journal (12-10-2021)“…Abstract Introduction Atrial fibrillation (AF) is the most common arrhythmia encountered in a hospital setting. However, there is little data on the…”
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Incidents between Straight-ahead Cyclists and Right-turning Motor Vehicles at Signalised Junctions
Published in Accident analysis and prevention (01-08-2017)“…•Staggered stop lines do not seem to reduce the number of right-turn accidents.•Staggered stop lines may reduce the number of right-turn accidents involving…”
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Agouti-related peptide-expressing neurons are mandatory for feeding
Published in Nature neuroscience (01-10-2005)“…Multiple hormones controlling energy homeostasis regulate the expression of neuropeptide Y (NPY) and agouti-related peptide (AgRP) in the arcuate nucleus of…”
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A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration
Published in Nature methods (01-06-2005)“…A new system for lineage ablation is based on transgenic expression of a diphtheria toxin receptor (DTR) in mouse cells and application of diphtheria toxin…”
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Myeloperoxidase in kidney disease
Published in Kidney international (01-12-2003)“…Myeloperoxidase in kidney disease. In glomerular and tubulointerstitial disease, polymorphonuclear- and monocyte-derived reactive oxygen species may contribute…”
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P06.09 In vitro assessment of human IL-12Fc function on porcine and canine peripheral blood mononuclear cells
Published in Neuro-oncology (Charlottesville, Va.) (01-05-2017)“…Introduction: Despite state-of-the-art surgical methods combined with radio- and chemotherapy the clinical prognosis of brain cancer patients remains poor. The…”
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Scottish science applications of Remote Electronic Monitoring
Published in ICES journal of marine science (01-05-2015)“…Part of the European Union (EU) Common Fisheries Policy revision of 2013 is a commitment to implement a land-all policy, under which the practice of discarding…”
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P09.10 Local immunotherapy of brain cancer harnessing high-retention Fc-fusion constructs
Published in Journal for immunotherapy of cancer (01-10-2020)“…BackgroundGlioblastoma is a highly aggressive cancer type and despite aggressive therapy, patients’ survival remains poor. Immunotherapy of brain cancer is…”
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Advancing the 3Rs: innovation, implementation, ethics and society
Published in Frontiers in veterinary science (15-06-2023)“…The 3Rs principle of replacing, reducing and refining the use of animals in science has been gaining widespread support in the international research community…”
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Critical functions for c-Myb at three checkpoints during thymocyte development
Published in Nature immunology (01-07-2004)“…The transcription factor c-Myb is expressed throughout T cell development in the thymus. However, little is understood about c-Myb function because of the…”
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Aberrant splicing of the tumor suppressor CYLD promotes the development of chronic lymphocytic leukemia via sustained NF-[kappa]B signaling
Published in Leukemia (01-01-2018)“…The pathogenesis of chronic lymphocytic leukemia (CLL) has been linked to constitutive NF-[kappa]B activation but the underlying mechanisms are poorly…”
Get full text
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Apoptosis of Oligodendrocytes via Fas and TNF-R1 Is a Key Event in the Induction of Experimental Autoimmune Encephalomyelitis
Published in The Journal of immunology (1950) (01-11-2005)“…In experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis, immunization with myelin Ags leads to demyelination and paralysis…”
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Experimental issues in the observation of water drop dynamics
Published in Physics letters. A (16-11-1998)“…The dripping faucet experiment is reexamined. High-speed video sequences reveal interesting dynamics, and expose the limitations of the traditional…”
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