Search Results - "Bucana, C. D."

Chemokine receptors in advanced breast cancer: differential expression in metastatic disease sites with diagnostic and therapeutic implications by Cabioglu, N., Sahin, A. A., Morandi, P., Meric-Bernstam, F., Islam, R., Lin, H. Y., Bucana, C. D., Gonzalez-Angulo, A. M., Hortobagyi, G. N., Cristofanilli, M.

“…Background: We investigated the expression of CXCR4, CCR7, estrogen receptor (ER), progesterone receptor (PR) and HER2-neu in human metastatic breast cancers…”
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Inhibited growth of colon cancer carcinomatosis by antibodies to vascular endothelial and epidermal growth factor receptors by SHAHEEN, R. M, AHMAD, S. A, LIU, W, REINMUTH, N, JUNG, Y. D, TSENG, W. W, DRAZAN, K. E, BUCANA, C. D, HICKLIN, D. J, ELLIS, L. M

“…Vascular endothelial growth factor (VEGF) and epidermal growth factor (EGF) regulate colon cancer growth and metastasis. Previous studies utilizing antibodies…”
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EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells by JUNG, Y. D, KIM, M. S, SHIN, B. A, CHAY, K. O, AHN, B. W, LIU, W, BUCANA, C. D, GALLICK, G. E, ELLIS, L. M

“…Catechins are key components of teas that have antiproliferative properties. We investigated the effects of green tea catechins on intracellular signalling and…”
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Blockade of NF-κB activity in human prostate cancer cells is associated with suppression of angiogenesis, invasion, and metastasis by Huang, Suyun, Pettaway, Curtis A, Uehara, Hisanori, Bucana, Corazon D, Fidler, Isaiah J

“…Since the NF-κB/relA transcription factor is constitutively activated in human prostate cancer cells, we determined whether blocking NF-κB/relA activity in…”
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Blockade of nuclear factor-κB signaling inhibits angiogenesis and tumorigenicity of human ovarian cancer cells by suppressing expression of vascular endothelial growth factor and interleukin 8 by SUYUN HUANG, ROBINSON, Jubilee B, DEGUZMAN, Ariel, BUCANA, Corazon D, FIDLER, Isaiah J

“…We determined whether blockade of nuclear factor (NF)- Kappa B/relA activity in human ovarian cancer cells can suppress angiogenesis and growth in an…”
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Platelet-Derived Endothelial Cell Growth Factor in Human Colon Cancer Angiogenesis: Role of Infiltrating Cells by Takahashi, Yutaka, Bucana, Corazon D., Liu, Wenbiao, Yoneda, Junya, Kitadai, Yasuhiko, Cleary, Karen R., Ellis, Lee M.

“…Background: Development of new blood vessels is essential for tumor growth and metastasis and depends on the production of angiogenic factors by tumor and/or…”
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Significance of vessel count and vascular endothelial growth factor and its receptor (KDR) in intestinal-type gastric cancer by TAKAHASHI, Y, CLEARY, K. R, MAI, M, KITADAI, Y, BUCANA, C. D, ELLIS, L. M

“…Angiogenesis is essential for tumor growth and metastasis and depends on the production of angiogenic factors by host and/or tumor cells. The role of…”
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Effects of combination anti-vascular endothelial growth factor receptor and anti-epidermal growth factor receptor therapies on the growth of gastric cancer in a nude mouse model by Jung, Y.D., Mansfield, P.F., Akagi, M., Takeda, A., Liu, W., Bucana, C.D., Hicklin, D.J., Ellis, L.M.

“…We hypothesised that the combination of anti-angiogenic and anti-epidermal growth factor (EFG)-receptor (R) therapies would more effectively inhibit gastric…”
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Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer by Takahashi, Y, Kitadai, Y, Bucana, C D, Cleary, K R, Ellis, L M

“…We studied the correlation between expression of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and their receptors with…”
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Expression of angiogenesis-related genes and progression of human ovarian carcinomas in nude mice by YONEDA, J, KUNIYASU, H, CRISPENS, M. A, PRICE, J. E, BUCANA, C. D, FIDLER, I. J

“…By the time patients are diagnosed with ovarian carcinoma, peritoneal dissemination of the tumor often has occurred. The progressive growth and spread of…”
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Level and function of epidermal growth factor receptor predict the metastatic potential of human colon carcinoma cells by RADINSKY, R, RISIN, S, FAN, D, ZHONGYUN DONG, BIELENBERG, D, BUCANA, C. D, FIDLER, I. J

“…The purpose of this study was to determine whether production of liver metastasis by human colon carcinoma (HCC) cells depends on the response of tumor cells…”
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Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis by SHAHEEN, R. M, DAVIS, D. W, WENBIAO LIU, ZEBROWSKI, B. K, WILSON, M. R, BUCANA, C. D, MCCONKEY, D. J, MCMAHON, G, ELLIS, L. M

“…Increased vascular endothelial growth factor (VEGF) expression is associated with colon cancer metastases. We hypothesized that inhibition of VEGF receptor…”
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Vessel counts and vascular endothelial growth factor expression in pancreatic adenocarcinoma by Ellis, L.M., Takahashi, Y., Fenoglio, C.J., Cleary, K.R., Bucana, C.D., Evans, D.B.

“…Angiogenesis is essential for growth and metastasis of solid malignancies. In several tumours, tumour vessel count and expression of vascular endothelial…”
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Expression of vascular endothelial growth factor is necessary but not sufficient for production and growth of brain metastasis by YANO, Seiji, SHINOHARA, Hisashi, HERBST, Roy S, KUNIYASU, Hiroki, BUCANA, Corazon D, ELLIS, Lee M, DAVIS, Darren W, MCCONKEY, David J, FIDLER, Isaiah J

“…We investigated the molecular mechanisms of angiogenesis in experimental brain metastasis. Cells from six different human cancer cell lines (proven to produce…”
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Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival by Reinmuth, Niels, Liu, Wenbiao, Jung, Young D., Ahmad, Syed A., Shaheen, Raymond M., Fan, Fan, Bucana, Corazon D., McMahon, Gerald, Gallick, Gary E., Ellis, Lee M.

“…ABSTRACT Small tumor vessels are composed of endothelial cells (ECs) surrounded by pericytes. Pericytes are believed to be an EC survival factor, but their…”
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Vascular endothelial growth factor is an in vivo survival factor for tumor endothelium in a murine model of colorectal carcinoma liver metastases by Bruns, Christiane J., Liu, Wenbiao, Davis, Darren W., Shaheen, Raymond M., McConkey, David J., Wilson, Michael R., Bucana, Corazon D., Hicklin, Daniel J., Ellis, Lee M.

“…BACKGROUND Recent studies have suggested that vascular endothelial growth factor (VEGF), in addition to its proangiogenic properties, also functions as a…”
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A Novel Putative Low-Affinity Insulin-like Growth Factor-binding Protein, LIBC (Lost in Inflammatory Breast Cancer), and RhoC GTPase Correlate with the Inflammatory Breast Cancer Phenotype by VAN GOLEN, K. L, DAVIES, S, ZHI FEN WU, YUNFANG WANG, BUCANA, C. D, ROOT, H, CHANDRASEKHARAPPA, S, STRAWDERMAN, M, ETHIER, S. P, MERAJVER, S. D

“…Inflammatory breast cancer is a rapidly growing, distinct form of locally advanced breast cancer that carries a guarded prognosis. To identify the genes that…”
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Interleukin 10 suppresses tumor growth and metastasis of human melanoma cells: potential inhibition of angiogenesis by S Huang, K Xie, C D Bucana, S E Ullrich, M Bar-Eli

“…Interleukin 10 (IL-10) inhibits the production of a wide range of cytokines in various cell types. The purpose of this study was to determine whether the…”
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Correlation of metastasis-related gene expression with metastatic potential in human prostate carcinoma cells implanted in nude mice using an in situ messenger RNA hybridization technique by Greene, GF, Kitadai, Y, Pettaway, CA, von Eschenbach, AC, Bucana, CD, Fidler, IJ

“…The purpose of this study was to determine whether the expression level of several metastasis-regulating genes correlates with the metastatic potential of…”
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Molecular Regulation of UVB-Induced Cutaneous Angiogenesis by Bielenberg, Diane R., Bucana, Corazon D., Sanchez, Ricardo, Donawho, Cherrie K., Kripke, Margaret L., Fidler, Isaiah J.

“…We determined whether cutaneous angiogenesis induced by exposure of mice to ultraviolet-B (UVB) radiation is associated with an imbalance between positive and…”
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