Search Results - "Bubenik, Jodi L"

RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2 by Zu, Tao, Cleary, John D., Liu, Yuanjing, Bañez-Coronel, Monica, Bubenik, Jodi L., Ayhan, Fatma, Ashizawa, Tetsuo, Xia, Guangbin, Clark, H. Brent, Yachnis, Anthony T., Swanson, Maurice S., Ranum, Laura P.W.

“…Several microsatellite-expansion diseases are characterized by the accumulation of RNA foci and RAN proteins, raising the possibility of a mechanistic…”
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Cell-type-specific dysregulation of RNA alternative splicing in short tandem repeat mouse knockin models of myotonic dystrophy by Nutter, Curtis A, Bubenik, Jodi L, Oliveira, Ruan, Ivankovic, Franjo, Sznajder, Łukasz J, Kidd, Benjamin M, Pinto, Belinda S, Otero, Brittney A, Carter, Helmut A, Vitriol, Eric A, Wang, Eric T, Swanson, Maurice S

“…Short tandem repeats (STRs) are prone to expansion mutations that cause multiple hereditary neurological and neuromuscular diseases. To study pathomechanisms…”
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Altered RNA Binding Activity Underlies Abnormal Thyroid Hormone Metabolism Linked to a Mutation in Selenocysteine Insertion Sequence-binding Protein 2 by Bubenik, Jodi L., Driscoll, Donna M.

“…The expression of selenoproteins requires the translational recoding of the UGA stop codon to selenocysteine. In eukaryotes, this requires an RNA stem loop…”
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Spaceflight effects on human vascular smooth muscle cell phenotype and function by Scotti, Marina M., Wilson, Brandon K., Bubenik, Jodi L., Yu, Fahong, Swanson, Maurice S., Allen, Josephine B.

“…The cardiovascular system is strongly impacted by the hazards of spaceflight. Astronauts spending steadily increasing lengths of time in microgravity are…”
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Myotonic dystrophy type 1 embryonic stem cells show decreased myogenic potential, increased CpG methylation at the DMPK locus and RNA mis-splicing by Franck, Silvie, Couvreu De Deckersberg, Edouard, Bubenik, Jodi L, Markouli, Christina, Barbé, Lise, Allemeersch, Joke, Hilven, Pierre, Duqué, Geoffrey, Swanson, Maurice S, Gheldof, Alexander, Spits, Claudia, Sermon, Karen D

“…Skeletal muscle tissue is severely affected in myotonic dystrophy type 1 (DM1) patients, characterised by muscle weakness, myotonia and muscle immaturity in…”
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Therapeutic targeting of RNA for neurological and neuromuscular disease by Bubenik, Jodi L, Scotti, Marina M, Swanson, Maurice S

“…Neurological and neuromuscular diseases resulting from familial, sporadic, or de novo mutations have devasting personal, familial, and societal impacts. As the…”
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N6-methyladenosine in 7SK small nuclear RNA underlies RNA polymerase II transcription regulation by Wang, Yuzhi, Traugot, Conner M., Bubenik, Jodi L., Li, Tianqi, Sheng, Peike, Hiers, Nicholas M., Fernandez, Paul, Li, Lu, Bian, Jiang, Swanson, Maurice S., Xie, Mingyi

“…N6-methyladenosine (m6A) modifications play crucial roles in RNA metabolism. How m6A regulates RNA polymerase II (RNA Pol II) transcription remains unclear. We…”
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RNA structure probing to characterize RNA-protein interactions on a low abundance pre-mRNA in living cells by Bubenik, Jodi L, Hale, Melissa, McConnell, Ona, Wang, Eric, Swanson, Maurice S, Spitale, Robert, Berglund, J Andrew

“…In vivo RNA structure analysis has become a powerful tool in molecular biology, largely due to the coupling of an increasingly diverse set of chemical…”
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Eukaryotic Initiation Factor 4a3 Is a Selenium-Regulated RNA-Binding Protein that Selectively Inhibits Selenocysteine Incorporation by Budiman, Michael E., Bubenik, Jodi L., Miniard, Angela C., Middleton, Lisa M., Gerber, Carri A., Cash, Ayla, Driscoll, Donna M.

“…The synthesis of selenoproteins requires the translational recoding of the UGA stop codon as selenocysteine. During selenium deficiency, there is a hierarchy…”
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Alternative Transcripts and 3′UTR Elements Govern the Incorporation of Selenocysteine into Selenoprotein S by Bubenik, Jodi L., Miniard, Angela C., Driscoll, Donna M.

“…Selenoprotein S (SelS) is a 189 amino acid trans-membrane protein that plays an important yet undefined role in the unfolded protein response. It has been…”
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Characterization of the UGA-recoding and SECIS-binding activities of SECIS-binding protein 2 by Bubenik, Jodi L, Miniard, Angela C, Driscoll, Donna M

“…Selenium, a micronutrient, is primarily incorporated into human physiology as selenocysteine (Sec). The 25 Sec-containing proteins in humans are known as…”
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Identification of a signature motif for the eIF4a3-SECIS interaction by Budiman, Michael E., Bubenik, Jodi L., Driscoll, Donna M.

“…eIF4a3, a DEAD-box protein family member, is a component of the exon junction complex which assembles on spliced mRNAs. The protein also acts as a…”
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Generation of a Novel SARS-CoV-2 Sub-genomic RNA Due to the R203K/G204R Variant in Nucleocapsid: Homologous Recombination has Potential to Change SARS-CoV-2 at Both Protein and RNA Level by Leary, Shay, Gaudieri, Silvana, Parker, Matthew D, Chopra, Abha, James, Ian, Pakala, Suman, Alves, Eric, John, Mina, Lindsey, Benjamin B, Keeley, Alexander J, Rowland-Jones, Sarah L, Swanson, Maurice S, Ostrov, David A, Bubenik, Jodi L, Das, Suman R, Sidney, John, Sette, Alessandro, de Silva, Thushan I, Phillips, Elizabeth, Mallal, Simon

“…Genetic variations across the SARS-CoV-2 genome may influence transmissibility of the virus and the host's anti-viral immune response, in turn affecting the…”
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Alternative transcripts and 3'UTR elements govern the incorporation of selenocysteine into selenoprotein S by Bubenik, Jodi L, Miniard, Angela C, Driscoll, Donna M

“…Selenoprotein S (SelS) is a 189 amino acid trans-membrane protein that plays an important yet undefined role in the unfolded protein response. It has been…”
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Known turnover and translation regulatory RNA-binding proteins interact with the 3' UTR of SECIS-binding protein 2 by Bubenik, Jodi, Ladd, Andrea, Gerber, Carri A., Budiman, Michael, Donna, Driscoll

“…The human selenoproteome is composed of ~25 selenoproteins, which cotranslationally incorporate selenocysteine, the 21st amino acid.  Selenoprotein expression…”
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N 6 -methyladenosine in 7SK small nuclear RNA underlies RNA polymerase II transcription regulation by Wang, Yuzhi, Traugot, Conner M, Bubenik, Jodi L, Li, Tianqi, Sheng, Peike, Hiers, Nicholas M, Fernandez, Paul, Li, Lu, Bian, Jiang, Swanson, Maurice S, Xie, Mingyi

“…N -methyladenosine (m A) modifications play crucial roles in RNA metabolism. How m A regulates RNA polymerase II (RNA Pol II) transcription remains unclear. We…”
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