Search Results - "Buatti, John"
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Survival in Patients With Brain Metastases: Summary Report on the Updated Diagnosis-Specific Graded Prognostic Assessment and Definition of the Eligibility Quotient
Published in Journal of clinical oncology (10-11-2020)“…Conventional wisdom has rendered patients with brain metastases ineligible for clinical trials for fear that poor survival could mask the benefit of otherwise…”
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Prostate-Specific Membrane Antigen (PSMA) Theranostics for Treatment of Oligometastatic Prostate Cancer
Published in International journal of molecular sciences (09-11-2021)“…Theranostics, a combination of therapy and diagnostics, is a field of personalized medicine involving the use of the same or similar radiopharmaceutical agents…”
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3D Slicer as an image computing platform for the Quantitative Imaging Network
Published in Magnetic resonance imaging (01-11-2012)“…Abstract Quantitative analysis has tremendous but mostly unrealized potential in healthcare to support objective and accurate interpretation of the clinical…”
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Beyond an Updated Graded Prognostic Assessment (Breast GPA): A Prognostic Index and Trends in Treatment and Survival in Breast Cancer Brain Metastases From 1985 to Today
Published in International journal of radiation oncology, biology, physics (01-06-2020)“…Brain metastases are a common sequelae of breast cancer. Survival varies widely based on diagnosis-specific prognostic factors (PF). We previously published a…”
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Deep segmentation networks predict survival of non-small cell lung cancer
Published in Scientific reports (21-11-2019)“…Non-small-cell lung cancer (NSCLC) represents approximately 80–85% of lung cancer diagnoses and is the leading cause of cancer-related death worldwide. Recent…”
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FDG PET based prediction of response in head and neck cancer treatment: Assessment of new quantitative imaging features
Published in PloS one (19-04-2019)“…18 F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is now a standard diagnostic imaging test performed in patients with head and neck cancer for…”
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Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer
Published in Cancer research (Chicago, Ill.) (15-12-2018)“…: Chemoradiation therapy is the mainstay for treatment of locally advanced, borderline resectable pancreatic cancer. Pharmacologic ascorbate (P-AscH , i.e.,…”
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Ketogenic Diets Enhance Oxidative Stress and Radio-Chemo-Therapy Responses in Lung Cancer Xenografts
Published in Clinical cancer research (15-07-2013)“…Ketogenic diets are high in fat and low in carbohydrates as well as protein which forces cells to rely on lipid oxidation and mitochondrial respiration rather…”
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O2⋅− and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate
Published in Cancer cell (10-04-2017)“…Pharmacological ascorbate has been proposed as a potential anti-cancer agent when combined with radiation and chemotherapy. The anti-cancer effects of…”
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Phase IIb, Randomized, Double-Blind Trial of GC4419 Versus Placebo to Reduce Severe Oral Mucositis Due to Concurrent Radiotherapy and Cisplatin For Head and Neck Cancer
Published in Journal of clinical oncology (01-12-2019)“…Oral mucositis (OM) remains a common, debilitating toxicity of radiation therapy (RT) for head and neck cancer. The goal of this phase IIb,…”
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Radiation Oncology and Radiopharmaceuticals: Making Our Own History While Learning From the Past
Published in International journal of radiation oncology, biology, physics (01-04-2023)Get full text
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12
Optimal Co-Segmentation of Tumor in PET-CT Images With Context Information
Published in IEEE transactions on medical imaging (01-09-2013)“…Positron emission tomography (PET)-computed tomography (CT) images have been widely used in clinical practice for radiotherapy treatment planning of the…”
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Graded Prognostic Assessment (GPA) for Patients With Lung Cancer and Brain Metastases: Initial Report of the Small Cell Lung Cancer GPA and Update of the Non-Small Cell Lung Cancer GPA Including the Effect of Programmed Death Ligand 1 and Other Prognostic Factors
Published in International journal of radiation oncology, biology, physics (01-09-2022)“…Patients with lung cancer and brain metastases represent a markedly heterogeneous population. Accurate prognosis is essential to optimally individualize care…”
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The Rapid Evolution of Theranostics in Radiation Oncology
Published in Seminars in radiation oncology (01-01-2021)Get full text
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Radioresistance in Glioblastoma and the Development of Radiosensitizers
Published in Cancers (03-09-2020)“…Ionizing radiation is a common and effective therapeutic option for the treatment of glioblastoma (GBM). Unfortunately, some GBMs are relatively radioresistant…”
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Surgical Management of Craniospinal Axis Solitary Fibrous Tumors: A Single-Institution Case Series and Comprehensive Review of the Literature
Published in Neurosurgery (01-02-2024)“…Meningeal solitary fibrous tumors (SFTs) comprise 0.4% of primary central nervous system neoplasms and carry metastatic potential. Disease course and optimal…”
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Machine learning with the TCGA-HNSC dataset: improving usability by addressing inconsistency, sparsity, and high-dimensionality
Published in BMC bioinformatics (17-06-2019)“…In the era of precision oncology and publicly available datasets, the amount of information available for each patient case has dramatically increased. From…”
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Training Requirements for Theranostics: A Unique Opportunity for Collaboration
Published in Journal of Nuclear Medicine (01-09-2019)Get full text
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Consuming a Ketogenic Diet while Receiving Radiation and Chemotherapy for Locally Advanced Lung Cancer and Pancreatic Cancer: The University of Iowa Experience of Two Phase 1 Clinical Trials
Published in Radiation research (01-06-2017)“…Ketogenic diets are low in carbohydrates and high in fat, which forces cells to rely more heavily upon mitochondrial oxidation of fatty acids for energy…”
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Radiation effects on retinal layers revealed by OCT, OCT-A, and perimetry as a function of dose and time from treatment
Published in Scientific reports (09-02-2024)“…Optical coherence tomography (OCT) has become a key method for diagnosing and staging radiation retinopathy, based mainly on the presence of fluid in the…”
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