Search Results - "Buard, Valerie"

Early and Late Protective Effect of Bone Marrow Mononuclear Cell Transplantation on Radiation-Induced Vascular Dysfunction and Skin Lesions by Holler, Valérie, Buard, Valerie, Roque, Telma, Squiban, Claire, Benderitter, Marc, Flamant, Stephane, Tamarat, Radia

“…Skin lesions caused by accidental exposure to radiation or by radiotherapy are a major clinical challenge. We evaluated the effect of bone marrow mononuclear…”
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Relevance of the TRIAP1/p53 axis in colon cancer cell proliferation and adaptation to glutamine deprivation by Nedara, Kenza, Reinhardt, Camille, Lebraud, Emilie, Arena, Giuseppe, Gracia, Céline, Buard, Valérie, Pioche-Durieu, Catherine, Castelli, Florence, Colsch, Benoit, Bénit, Paule, Rustin, Pierre, Albaud, Benoit, Gestraud, Pierre, Baulande, Sylvain, Servant, Nicolas, Deutsch, Eric, Verbavatz, Jean-Marc, Brenner, Catherine, Milliat, Fabien, Modjtahedi, Nazanine

“…Human TRIAP1 (TP53-regulated inhibitor of apoptosis 1; also known as p53CSV for p53-inducible cell survival factor) is the homolog of yeast Mdm35, a well-known…”
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Mesenchymal stem cells limit vascular and epithelial damage and restore the impermeability of the urothelium in chronic radiation cystitis by Brossard, Clément, Pouliet, Anne-Laure, Lefranc, Anne-Charlotte, Benadjaoud, Mohamedamine, Dos Santos, Morgane, Demarquay, Christelle, Buard, Valerie, Benderitter, Marc, Simon, Jean-Marc, Milliat, Fabien, Chapel, Alain

“…Cellular therapy seems to be an innovative therapeutic alternative for which mesenchymal stem cells (MSCs) have been shown to be effective for interstitial and…”
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Pravastatin Limits Radiation-Induced Vascular Dysfunction in the Skin by Holler, Valerie, Buard, Valerie, Gaugler, Marie-Helene, Guipaud, Olivier, Baudelin, Cedric, Sache, Amandine, Perez, Maria del R., Squiban, Claire, Tamarat, Radia, Milliat, Fabien, Benderitter, Marc

“…About half of people with cancer are treated with radiation therapy; however, normal tissue toxicity still remains a dose-limiting factor for this treatment…”
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PAI-1-dependent endothelial cell death determines severity of radiation-induced intestinal injury by Abderrahmani, Rym, François, Agnes, Buard, Valerie, Tarlet, Georges, Blirando, Karl, Hneino, Mohammad, Vaurijoux, Aurelie, Benderitter, Marc, Sabourin, Jean-Christophe, Milliat, Fabien

“…Normal tissue toxicity still remains a dose-limiting factor in clinical radiation therapy. Recently, plasminogen activator inhibitor type 1 (SERPINE1/PAI-1)…”
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Essential Role of Plasminogen Activator Inhibitor Type-1 in Radiation Enteropathy by Milliat, Fabien, Sabourin, Jean-Christophe, Tarlet, Georges, Holler, Valerie, Deutsch, Eric, Buard, Valérie, Tamarat, Radia, Atfi, Azeddine, Benderitter, Marc, François, Agnès

“…Intestinal radiation injury is a dose-limiting factor in radiation therapy for abdominal and pelvic cancers. Because transforming growth factor-β1 is a key…”
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The TGF-β/Smad repressor TG-interacting factor 1 (TGIF1) plays a role in radiation-induced intestinal injury independently of a Smad signaling pathway by Hneino, Mohammad, François, Agnes, Buard, Valerie, Tarlet, Georges, Abderrahmani, Rym, Blirando, Karl, Hoodless, Pamela A, Benderitter, Marc, Milliat, Fabien

“…Despite advances in radiation delivery protocols, exposure of normal tissues during the course of radiation therapy remains a limiting factor of cancer…”
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Plasminogen Activator Inhibitor-1 Controls Bone Marrow-Derived Cells Therapeutic Effect Through MMP9 Signaling: Role in Physiological and Pathological Wound Healing by Ebrahimian, Teni G., Squiban, Claire, Roque, Telma, Lugo-Martinez, Haydee, Hneino, Mohamad, Buard, Valerie, Gourmelon, Patrick, Benderitter, Marc, Milliat, Fabien, Tamarat, Radia

“…We assessed the role of plasminogen activator inhibitor‐1 (PAI‐1) and matrix metalloproteinase 9 (MMP9) in wound healing process and in the bone marrow…”
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Human keratinocyte radiosensitivity is linked to redox modulation by Isoir, Muriel, Buard, Valérie, Gasser, Philippe, Voisin, Philippe, Lati, Elian, Benderitter, Marc

“…Ionising radiation-induced reactive oxygen species (ROS) overproduction induces keratinocyte alterations and constitutes one of the most common effects after…”
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Preclinical Model of Stereotactic Ablative Lung Irradiation Using Arc Delivery in the Mouse: Effect of Beam Size Changes and Dose Effect at Constant Collimation by Bertho, Annaïg, Dos Santos, Morgane, Buard, Valérie, Paget, Vincent, Guipaud, Olivier, Tarlet, Georges, Milliat, Fabien, François, Agnès

“…Stereotactic body radiation therapy is a therapeutic option offered to high surgical risk patients with lung cancer. Focal lung irradiation in mice is a new…”
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Deciphering the Dynamic Molecular Program of Radiation-Induced Endothelial Senescence by Benadjaoud, Mohamed Amine, Soysouvanh, Frédéric, Tarlet, Georges, Paget, Vincent, Buard, Valérie, Santos de Andrade, Henrique, Morilla, Ian, Dos Santos, Morgane, Bertho, Annaïg, l'Homme, Bruno, Gruel, Gaëtan, François, Agnès, Mondini, Michele, Deutsch, Eric, Guipaud, Olivier, Milliat, Fabien

“…Radiation-induced cellular senescence is a double-edged sword, acting as both a tumor suppression process limiting tumor proliferation, and a crucial process…”
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Stereotactic Lung Irradiation in Mice Promotes Long-Term Senescence and Lung Injury by Soysouvanh, Frédéric, Benadjaoud, Mohamed Amine, Dos Santos, Morgane, Mondini, Michele, Lavigne, Jérémy, Bertho, Annaïg, Buard, Valérie, Tarlet, Georges, Adnot, Serge, Deutsch, Eric, Guipaud, Olivier, Paget, Vincent, François, Agnès, Milliat, Fabien

“…Lung cancer will be treated more frequently using stereotactic body radiation therapy, and preclinical research to model long-term toxicity of ablative doses…”
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Radiation-induced changes in the glycome of endothelial cells with functional consequences by Jaillet, Cyprien, Morelle, Willy, Slomianny, Marie-Christine, Paget, Vincent, Tarlet, Georges, Buard, Valérie, Selbonne, Sonia, Caffin, Fanny, Rannou, Emilie, Martinez, Pierre, François, Agnès, Foulquier, François, Allain, Fabrice, Milliat, Fabien, Guipaud, Olivier

“…As it is altered by ionizing radiation, the vascular network is considered as a prime target in limiting normal tissue damage and improving tumor control in…”
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In vivo evidence for an endothelium-dependent mechanism in radiation-induced normal tissue injury by Rannou, Emilie, François, Agnès, Toullec, Aurore, Guipaud, Olivier, Buard, Valérie, Tarlet, Georges, Mintet, Elodie, Jaillet, Cyprien, Iruela-Arispe, Maria Luisa, Benderitter, Marc, Sabourin, Jean-Christophe, Milliat, Fabien

“…The pathophysiological mechanism involved in side effects of radiation therapy and especially the role of the endothelium remains unclear. Previous results…”
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Temporal clustering analysis of endothelial cell gene expression following exposure to a conventional radiotherapy dose fraction using Gaussian process clustering by Heinonen, Markus, Milliat, Fabien, Benadjaoud, Mohamed Amine, François, Agnès, Buard, Valérie, Tarlet, Georges, d'Alché-Buc, Florence, Guipaud, Olivier

“…The vascular endothelium is considered as a key cell compartment for the response to ionizing radiation of normal tissues and tumors, and as a promising target…”
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Endothelial Hey2 deletion reduces endothelial-to-mesenchymal transition and mitigates radiation proctitis in mice by Mintet, Elodie, Lavigne, Jérémy, Paget, Vincent, Tarlet, Georges, Buard, Valérie, Guipaud, Olivier, Sabourin, Jean-Christophe, Iruela-Arispe, Maria-Luisa, Milliat, Fabien, François, Agnès

“…The current study evaluated the role of Hey2 transcription factor in radiation-induced endothelial-to-mesenchymal transition (EndoMT) and its impact on…”
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Twenty years of FISH-based translocation analysis for retrospective ionizing radiation biodosimetry by Grégoire, Eric, Roy, Laurence, Buard, Valérie, Delbos, Martine, Durand, Valérie, Martin-Bodiot, Cécile, Voisin, Pascale, Sorokine-Durm, Irène, Vaurijoux, Aurélie, Voisin, Philippe, Baldeyron, Céline, Barquinero, Joan Francesc

“…Purpose: The fluorescent in situ hybridization (FISH) technique, which easily detects reciprocal translocations, is currently used to estimate doses in…”
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Multiparametric radiobiological assays show that variation of X-ray energy strongly impacts relative biological effectiveness: comparison between 220 kV and 4 MV by Paget, Vincent, Ben Kacem, Mariam, Dos Santos, Morgane, Benadjaoud, Mohamed A., Soysouvanh, Frédéric, Buard, Valérie, Georges, Tarlet, Vaurijoux, Aurélie, Gruel, Gaëtan, François, Agnès, Guipaud, Olivier, Milliat, Fabien

“…Based on classic clonogenic assay, it is accepted by the scientific community that, whatever the energy, the relative biological effectiveness of X-rays is…”
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Lung Stereotactic Arc Therapy in Mice: Development of Radiation Pneumopathy and Influence of HIF-1α Endothelial Deletion by Lavigne, Jérémy, Suissa, Alexandra, Verger, Nicolas, Dos Santos, Morgane, Benadjaoud, Mohamedamine, Mille-Hamard, Laurence, Momken, Iman, Soysouvanh, Frédéric, Buard, Valérie, Guipaud, Olivier, Paget, Vincent, Tarlet, Georges, Milliat, Fabien, François, Agnès

“…Stereotactic body radiation therapy offers good lung local tumor control by the administration of a high dose per fraction in small volumes. Stereotactic body…”
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Identification of Endothelial-to-Mesenchymal Transition as a Potential Participant in Radiation Proctitis by Mintet, Elodie, Rannou, Emilie, Buard, Valérie, West, Gail, Guipaud, Olivier, Tarlet, Georges, Sabourin, Jean-Christophe, Benderitter, Marc, Fiocchi, Claudio, Milliat, Fabien, François, Agnès

“…The endothelial-to-mesenchymal transition (EndoMT) is a crucial cellular process during heart development necessary to the formation of cardiac valves. This…”
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