Search Results - "Buadze, T."

Epigenetic Activation of Ribosomal Cistrons in Chromatids of Acrocentric Chromosome 15 in Lung Cancer by Lezhava, T., Buadze, T., Mikaia, N., Jokhadze, T., Sigua, T., Gaiozishvili, M., Melkadze, T.

“…After the Human Genome Project was declared complete, the strategic focus area of contemporary genetics shifted towards functional genomics whose research…”
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EPIGENETIC MODIFICATION UNDER THE INFLUENCE OF PEPTIDE BIOREGULATORS ON "AGED" HETEROCHROMATIN by Lezhava, T, Jokhadze, T, Monaselidze, J, Buadze, T, Gaiozishvili, M, Sigua, T

“…Following the completion of the Human Genome Project, the strategic direction of modern genetics has moved toward functional genomics, to explore the functions…”
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Epigenetic Changes of Activity of the Ribosomal Cistrons of Human Acrocentric Chromatids in Fetuses, Middle-aged (22–45 years) and Old Individuals (80–106 years) by Lezhava, T., Buadze, T., Monaselidze, J., Jokhadze, T., Sigua, N., Jangulashvili, N., Gaiozishvili, M., Koridze, M., Zosidze, N., Rukhadze, M.

“…The level of total heterochromatin, Ag-positive nucleolar organiser regions (NORs) heterochromatin, non-associated and associated heterochromatin satellite…”
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Functional regulation of genome with peptide bioregulators by hypertrophic cardiomyopathy (by patients and relatives) by Dzhokhadze, T A, Buadze, T Zh, Gaĭozishvili, M N, Rogava, M A, Lazhava, T A

“…In this paper, a comparative study of the functional genome indicators using lymphocyte cultures of patients with hypertrophic cardiomyopathy (HCM) and their…”
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Natural and artefactual aneuploidy in human lymphocytes in extreme old age by Lezhava, T, Khmaladze, E, Lokhadze, T, Buadze, T

“…At present it is generally believed that aging is accompanied by an increase in the numbers of cells with altered chromosome sets. However, the problem of…”
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Association of genes polymorphisms with warfarin dose requirement in georgian population by Tchitashvili, G., Kakauridze, N., Buadze, T., Gaiozishvili, M., Lezhava, T.

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Variability of radiation-induced adaptive response in old age individuals and their correction by Peptide bioregulator -Livagen by Dzhokhadze, T A, Buadze, T Zh, Dvalishvili, N A, Lezhava, T A

“…Effect of aging on adaptive response of cellular systems to low (stimulated) dozes of gamma-rays (0, 2 and 0, 5 Gy) and to disturbing dozes of radiation (1 and…”
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Anti-aging peptide bioregulators induce reactivation of chromatin by Lezhava, T, Monaselidze, J, Kadotani, T, Dvalishvili, N, Buadze, T

“…The effect of synthetic peptide bioregulators (Epitalon, Livagen and Vilon) on structural and facultative heterochromatin of cultivated lymphocytes have been…”
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Instability of genome in atherosclerosis by Gaiozishvili, M., Kakauridze, N., Buadze, T., Sigua, T., Jokhadze, T., Lezhava, T.

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EPIGENETIC MODIFICATION UNDER THE INFLUENCE OF PEPTIDE BIOREGULATORS ON THE "OLD" CHROMATIN by Lezhava, T, Jokhadze, T, Monaselidze, J, Buadze, T, Gaiozishvili, M, Sigua, T, Khujadze, I, Gogidze, K, Mikaia, N, Chigvinadze, N

“…In the present study, on the one hand, the epigenetic modification of condensed "old" chromatin was determined, and on the other hand, the influence of peptide…”
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FREQUENCY OF POLYMORPHIC VARIANTS OF GSTT1 AND GSTM1 GENES IN PATIENTS WITH PULMONARY TUBERCULOSIS IN GEORGIAN POPULATION by Jokhadze, T, Buadze, T, Gaiozishvili, M, Kiria, N, Khujadze, I, Lezhava, T

“…A study was made for determining the frequencies of polymorphic variants of GST genes - GSTM1 and GSTT1, both among healthy individuals of the Georgian…”
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FREQUENCY OF POLYMORPHISM OF VKORC1 AND CYP2C9 GENES IN TWO REGIONS OF GEORGIA by Jokhadze, T, Kakauridze, N, Buadze, T, Gaiozishvili, M, Lezhava, T

“…The aim of the research was to study the frequency of VKROC1 and CYP2C9 genes different alleles for healthy donors and for patients with thrombosis, in two…”
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EVALUATION OF GENOMIC PARAMETERS IN DUCTAL BREAST CANCER PATIENTS AND THE ABILITY OF IT'S CORRECTION by Jokhadze, T, Gaiozishvili, M, Buadze, T, Sigua, T, Namchelvadze, E, Lezhava, T

“…The level of DNA single strand breaks, chromosomal abnormalities and sister chromatid exchanges and the possibility of its normalization with oligopeptide…”
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GENOMIC VARIABILITY IN PATIENTS WITH DUCTAL FORM OF BREAST CANCER AND THE POSSIBILITY OF CORRECTION THE PEPTIDE BIOREGULATOR AND METAL IONS by Jokhadze, T, Monaselidze, J, Nemsadze, G, Buadze, T, Gaiozishvili, M, Lezhava, T

“…Level of genome stability (structural aberrations, aneuploidy and fragile sites) was studied in cells of the lymphocyte culture of ductal breast cancer…”
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GENOMIC VARIABILITY DURING PREGNANCY TRIMESTERS by Jokhadze, T, Buadze, T, Gaiozishvili, M, Mosidze, S, Sigua, T, Lezhava, T

“…The article presents data on the genome status of pregnant women in different trimesters of pregnancy, during the normal course of pregnancy. The variability…”
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Genomic instability in atherosclerosis by Dzhokhadze, T A, Buadze, T Zh, Gaiozishvili, M N, Kakauridze, N G, Lezhava, T A

“…A comparative study of the level of genomic instability, parameters of quantitative and structural mutations of chromosomes (aberration, aneuploidy,…”
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Genome instability in pulmonary tuberculosis before and after treatment by Dzhokhadze, T A, Buadze, T Zh, Rubanov, K Dzh, Kiriia, N A, Lezhava, T A

“…Pulmonary tuberculosis is classified as a disease with a genetic predisposition, and therefore, as with other pathologies related to this group of diseases, by…”
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Deheterochromatinization of the chromatin in old age induced by oligopeptide bioregulator (Lys-Glu-Asp-Pro) by Dzhokhadze, T A, Buadze, T Zh, Gaĭozishvili, M N, Baratashvili, N A, Lezhava, T A

“…In this work is presented the data on the variability of the functional characteristics of the chromosomes in the cells exposed by oligopeptide bioregulator -…”
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