Search Results - "Bu, Hualei"

FOXD1 is targeted by miR-30a-5p and miR-200a-5p and suppresses the proliferation of human ovarian carcinoma cells by promoting p21 expression in a p53-independent manner by Wang, Yu, Qiu, Chunping, Lu, Nan, Liu, Zhaojian, Jin, Chengjuan, Sun, Chenggong, Bu, Hualei, Yu, Hongfeng, Dongol, Samina, Kong, Beihua

“…High-grade serous ovarian carcinoma (HGSOC) accounts for the highest number of deaths among patients with epithelial ovarian cancer. However, the molecular…”
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Niraparib exhibits a synergistic anti-tumor effect with PD-L1 blockade by inducing an immune response in ovarian cancer by Meng, Jinyu, Peng, Jin, Feng, Jie, Maurer, Jochen, Li, Xiao, Li, Yan, Yao, Shu, Chu, Ran, Pan, Xiyu, Li, Junting, Zhang, Ting, Liu, Lu, Zhang, Qing, Yuan, Zeng, Bu, Hualei, Song, Kun, Kong, Beihua

“…Abstract Background Immune checkpoint blockades (ICBs) therapy showed limited efficacy in ovarian cancer management. Increasing evidence indicated that…”
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Severe hyponatremia in preeclampsia: a case report and review of the literature by Pu, Yingying, Wang, Xia, Bu, Hualei, Zhang, Wenzhe, Lu, Ruihui, Zhang, Shuquan

“…Purpose To summarize the clinical characteristics and treatments of preeclampsia complicated with hyponatremia. Methods We reported a new case of preeclampsia…”
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The First Nationwide Multicenter Prevalence Study of Germline BRCA1 and BRCA2 Mutations in Chinese Ovarian Cancer Patients by Wu, Xiaohua, Wu, Lingying, Kong, Beihua, Liu, Jihong, Yin, Rutie, Wen, Hao, Li, Ning, Bu, Hualei, Feng, Yanling, Li, Qingli, Lu, Xuesong, Wei, Jia, Zhu, Xuehua, Mills, John, Ellison, Gillian, Gutjahr, Thorsten, Liu, Yuzhen

“…Subjects with germline BRCA1/2 mutations (gBRCAm) have an increased risk of developing ovarian cancer and enhanced sensitivity to platinum-containing agents…”
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Development and Validation of an Immune-Related Prognostic Signature in Cervical Cancer by Su, Rongjia, Jin, Chengwen, Bu, Hualei, Xiang, Jiangdong, Zhou, Lina, Jin, Chengjuan

“…Cervical cancer is the fourth most frequent gynecological malignancy across the world. Immunotherapies have proved to improve prognosis of cervical cancer…”
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Successful pregnancy after complete resection of leiomyomatosis peritonealis disseminate without recurrence:a case report with next-generation sequencing analysis and literature review by Bu, Hualei, Jin, Chengjuan, Fang, Yan, Ma, Yana, Wang, Xiao, Chen, Jingying, Chen, Lijun

“…Peritoneal leiomyomatosis disseminate (LPD) is a rare disease characterized by widespread dissemination of leiomyomas nodules throughout the peritoneal and…”
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Effects of Neoadjuvant Chemotherapy in Ovarian Cancer Patients With Different Germline BRCA1/2 Mutational Status: A Retrospective Cohort Study by Fu, Mengdi, Jin, Chengjuan, Feng, Shuai, Jia, Zongyang, Nie, Lekai, Zhang, Yang, Peng, Jin, Wang, Xia, Bu, Hualei, Kong, Beihua

“…Whether neoadjuvant chemotherapy (NAC) followed by interval debulking surgery (IDS) against primary debulking surgery (PDS) has a differential effect on…”
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Efficacy of poly (ADP-ribose) polymerase inhibitors monotherapy and the impact to subsequent platinum-based chemotherapy in breast cancer susceptibility genes1/2-mutated ovarian cancer patients with secondary platinum-sensitive relapse by Ma, Yana, Liu, Jiale, Li, Ning, Bu, Hualei, Huang, Yongwen, Jin, Chengjuan, Wen, Hao, Feng, Shuai, Zhang, Hui, Yang, Xiaorong, Kong, Beihua, Wu, Lingying, Song, Kun

“…Abstract Background The therapeutic effect of poly (ADP-ribose) polymerase inhibitors (PARPi) monotherapy compared with platinum-based chemotherapy, and the…”
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BRCA mutation frequency and clinical features of ovarian cancer patients: A report from a Chinese study group by Bu, Hualei, Chen, Jingying, Li, Qingshui, Hou, Jianqing, Wei, Yuan, Yang, Xiaohang, Ma, Yana, He, Hongsheng, Zhang, Youzhong, Kong, Beihua

“…Aim Subjects with germline BRCA1/2 mutations (gBRCAm) have an increased risk of developing breast cancer and ovarian cancer. At present, knowledge of BRCA1/2…”
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Clinical features and prognostic factors analysis of intravenous leiomyomatosis by Chen, Jingying, Bu, Hualei, Zhang, Zhaoyang, Chu, Ran, Qi, Gonghua, Zhao, Chen, Wang, Qiuman, Ma, Xinyue, Wu, Huan, Dou, Zhiyuan, Wang, Xia, Kong, Beihua

“…The treatment and prognostic factors of intravenous leiomyomatosis (IVL) remain lacking systematic evidence. A retrospective study was conducted on IVL…”
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Parallel Loop Binding Compression Suture, a Modified Procedure for Pernicious Placenta Previa Complicated With Placenta Increta by Fu, Mengdi, Bu, Hualei, Fang, Yan, Wang, Chunling, Zhang, Li, Zhang, Yang, Sun, Xiao, Li, Mingbao, Jin, Chengjuan, Xu, Yintao, Chen, Lijun

“…To evaluate the efficacy and safety of parallel loop binding compression suture of the lower uterus during cesarean section in pernicious placenta previa…”
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Differences in clinical features between CA-125 and RECIST progression in patients with ovarian cancer treated with PARP inhibitors by Ma, Yana, Lv, Weiwei, Bu, Hualei, Kong, Beihua, Song, Kun

“…e17568 Background: The clinical features of disease progression (PD) based on Response Evaluation Criteria in Solid Tumors (RECIST) and carbohydrate antigen…”
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Different disease progression patterns based on RECIST and CA-125 criteria and the impact on prognosis in patients with ovarian cancer treated with PARP inhibitors by Song, Kun, Ma, Yana, Bu, Hualei, Zhang, Yawen

“…e17536 Background: We aimed to assess the clinical features of disease progression (PD) based on Response Evaluation Criteria in Solid Tumors (RECIST) and…”
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Antiangiogenic Strategies in Epithelial Ovarian Cancer: Mechanism, Resistance, and Combination Therapy by Jin, Chengwen, Yuan, Mingyuan, Bu, Hualei, Jin, Chengjuan

“…Angiogenesis is one of the hallmarks of cancer and plays a crucial role in carcinogenesis and progression of epithelial ovarian cancer. Antiangiogenic agent is…”
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Association between coffee and tea consumption and ovarian cancer incidence: A prospective analysis in the PLCO dataset by Huang, Changzhen, Bu, Hualei, Wang, Yuanjian, Chu, Ran, Zhao, Wenna, Liu, Yan, Wu, Han, Yao, Shu

“…Epidemiological evidence regarding the relationship between coffee and tea consumption and the risk of ovarian cancer (OC) is inconsistent. Therefore, we aimed…”
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Cyclin F and KIF20A, FOXM1 target genes, increase proliferation and invasion of ovarian cancer cells by Li, Yingwei, Guo, Haiyang, Wang, Zixiang, Bu, Hualei, Wang, Shourong, Wang, Hao, Fang, Haiyan, Liu, Zhaojian, Kong, Beihua

“…Increased expression of FOXM1 is observed in a variety of human malignancies. The downstream target genes of FOXM1 involved in tumorigenesis and development…”
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Overexpression of PRC1 indicates a poor prognosis in ovarian cancer by Bu, Hualei, Li, Yingwei, Jin, Chengjuan, Yu, Hongfeng, Wang, Xiangxiang, Chen, Jingying, Wang, Yu, Ma, Yana, Zhang, Youzhong, Kong, Beihua

“…Protein regulator of cytokinesis-1 (PRC1) is a microtubule-associated factor involved in cytokinesis. Recent studies have indicated that PRC1 overexpression is…”
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Efficacy and safety of 9 MW2821, an antibody-drug conjugate targeting Nectin-4 monotherapy, in patients with recurrent or metastatic cervical cancer: A multicenter, open-label, phase I/II study by Yang, Huijuan, Zhang, Jian, Liu, Rujiao, Gao, Shuiping, Lou, Hanmei, Li, Guiling, Bu, Hualei, Li, Rong, Wang, Shanbing, Shen, Shujing, Zhang, Mingjun, Wang, Peipei, Feng, Zhe, Chu, Nan

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An Open-label, Multicenter, Single-arm, Phase II Study of Fluzoparib in Patients with Germline BRCA1/2 Mutation and Platinum-sensitive Recurrent Ovarian Cancer by Li, Ning, Bu, Hualei, Liu, Jihong, Zhu, Jianqing, Zhou, Qi, Wang, Li, Yin, Rutie, Wu, Xiaohua, Yao, Shuzhong, Gu, Kangsheng, Zhang, Hui, Li, Guiling, Pan, Hongming, Wu, Qiang, An, Ruifang, Yang, Xinfeng, Zhu, Yaping, Wan, Xiaoping, Duan, Wei, Xiong, Jianping, Guo, Hongyan, Lou, Ge, Wang, Jing, Hu, Wenjing, Zhang, Xin, Meng, Yuanguang, Zhang, Ben, Wang, Yuting, Wang, Quanren, Wu, Lingying

“…Fluzoparib (PARP inhibitor) showed promising antitumor activity for advanced ovarian cancer in a phase I study. This study aimed to assess the efficacy and…”
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9MW2821, a nectin-4 antibody-drug conjugate (ADC), in patients with advanced solid tumor: Results from a phase 1/2a study by Zhang, Jian, Liu, Rujiao, Gao, Shuiping, Yang, Huijuan, Chen, Jian, Yuan, Fang, Liu, Jiyan, Guo, Hongqian, Zhang, Shun, Li, XingYa, Yao, Xin, Bai, Ming, Bu, Hualei, Li, Yinyin, Hu, Changlu, Li, Xiumin, Wang, Zhen, Wang, ShanBing, Lou, Hanmei, Feng, Zhe

“…3013 Background: 9MW2821 is a monoclonal ADC that delivers monomethyl auristatin E to cells expressing Nectin-4. Nectin-4 is an adhesion molecule that highly…”
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