Search Results - "Bryzgalov, L. O."

The Search for and Functional Analysis of Genetic Variants in microRNA-Binding Sites using Massively Parallel Reporter Assay by Rykova, E. Yu, Ershov, N. I., Degtyareva, A. O., Bryzgalov, L. O., Lushnikova, E. L.

“…A large-scale search for the genetic variants with a bias in the representation of alleles in transcriptome data (AE SNPs) and the binding sites in microRNA…”
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The functional insight into the genetics of cardiovascular disease: results from the post-GWAS study by Bryzgalov, L O, Korbolina, E E, Damarov, I S, Merkulova, T I

“…Cardiovascular diseases (CVDs), the leading cause of death worldwide, generally refer to a range of pathological conditions with the involvement of the heart…”
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Detection of target genes of FOXA transcription factors involved in proliferation control by Bryzgalov, L. O, Ershov, N. I, Oshchepkov, D. Yu, Kaledin, V. I, Merkulova, T. I

“…To reveal the mechanism of tumor-suppressing activity of FOXA proteins in liver, a search for potential target genes of these transcription factors involved in…”
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Detection of target genes of FOXA transcription factors involved in proliferation control by Bryzgalov, L O, Ershov, N I, Oshchepkov, D Yu, Kaledin, V I, Merkulova, T I

“…To reveal the mechanism of tumor-suppressing activity of FOXA proteins in liver, a search for potential target genes of these transcription factors involved in…”
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Detection of new regulatory SNPs associated with colorectal cancer predisposition by Leberfarb, E. Yu, Bryzgalov, L. O., Brusentsov, I. I., Merkulova, T. I.

“…A new approach to the search for regulatory SNPs (rSNPs) based on the use of ENCODE project data on ChIP-seq and RNA-seq experiments was developed. The…”
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Epigenetic «probes» for lung cancer monitoring: LINE-1 methylation pattern in blood- circulating DNA by A. A. Ponomaryova, Е. Y. Rykova, N. V. Cherdyntseva, A. A. Bondar, A. Y. Dobrodeev, A. A. Zavyalov, S. A. Tuzikov, L. O. Bryzgalov, T. I. Merkulova, V. V. Vlassov, P. P. Laktionov

“…Malignant cell transformation is accompanied by two processes of DNA methylation changes: promoter hypermethylation of specific genes and hypomethylation of…”
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FOXA transcription factors determine the amplitude of glucocorticoid induction of tyrosine aminotransferase in mice by Bryzgalov, L O, Ershov, N I, Ilnitskaya, S I

“…o-Aminoazotoluene was more potent than 3'-methyl-4-dimethylaminoazobenzene in modulating glucocorticoid induction of tyrosine aminotransferase and DNA-binding…”
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Development of computational methods to search for FoxA transcription factor binding sites, their experimental verification and application to the analysis of ChIP-seq data by Levitsky, V. G., Oshchepkov, D. Yu, Ershov, N. I., Bryzgalov, L. O., Antontseva, E. V., Vasiliev, G. V., Merkulova, T. I., Kolchanov, N. A.

“…Transcription factors of the FoxA family play a key role in early embryogenesis, organogenesis, and main tenance of metabolic homeostasis of the organism [1]…”
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The unknown nuclear protein that decreases HNF3 activity ensures species specificity of action of hepatocarcinogenic amino azo dyes by Kropachev, K Yu, Pakharukova, M Yu, Bryzgalov, L O, Kaledin, V I, Kobzev, V F, Merkulova, T I

“…(ProQuest: Abstract omitted; see image)[PUBLICATION ABSTRACT]…”
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Epigenetic probes for lung cancer monitoring: Line-1 methylation pattern in blood-circulating DNA by Ponomaryova, A. A., Rykova, E. Y., Cherdyntseva, N. V., Bondar, A. A., Dobrodeev, A. Y., Zavyalov, A. A., Tuzikov, S. A., Bryzgalov, L. O., Merkulova, T. I., Vlassov, V. V., Laktionov, P. P.

“…The main components of DNA aberrant methylation in malignant cells are promoter hypermethylation of specific genes and hypomethylation of the main part of DNA,…”
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rSNP_Guide-based evaluation of SNPs in promoters of the human APC and MLH1 genes associated with colon cancer by Rasskazov, D. A., Antontseva, E. V., Bryzgalov, L. O., Matveeva, M. Yu, Kashina, E. V., Ponomarenko, P. M., Orlova, G. V., Ponomarenko, M. P., Afonnikov, D. A., Merkulova, T. I.

“…We examined six regulatory SNPs (Single Nucleotide Polymorphisms) of two human genes, APC and MLH1 (rs75996864, rs76241113, rs78037487, rs80112297, rs80313086,…”
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Search for regulatory SNPs associated with colon cancer in the APC and MLH1 genes by Antontseva, E. V., Bryzgalov, L. O., Matveeva, M. Yu, Kashina, E. V., Cherdyntseva, N. V., Merkulova, T. I.

“…Polymorphisms belonging to the regulatory regions of the APC and MLH1 genes were detected by invoking ChIP-Seq data obtained in the ENCODE project. The…”
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rSNP_Guide-BASED EVALUATION OF SNPs IN PROMOTеRS OF THE HUMAN APC AND MLH1 GENES ASSOCIATED WITH COLON CANCER by D. A. Rasskazov, E. V. Antontseva, L. O. Bryzgalov, M. Yu. Matveeva, E. V. Kashina, P. M. Ponomarenko, G. V. Orlova, M. P. Ponomarenko, D. A. Afonnikov, T. I. Merkulova

“…Six regulatory SNPs (single nucleotide polymorphisms) of two human APC and MLH1 genes (rs75996864, rs76241113, rs78037487, rs80112297, rs80313086 and…”
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Program complex SNP-MED for analysis of single-nucleotide polymorphism (SNP) effects on the function of genes associated with socially significant diseases by Podkolodnyy, N. L., Afonnikov, D. A., Vaskin, Yu. Yu, Bryzgalov, L. O., Ivanisenko, V. A., Demenkov, P. S., Ponomarenko, M. P., Rasskazov, D. A., Gunbin, K. V., Protsyuk, I. V., Shutov, I. Yu, Leontyev, P. N., Fursov, M. Yu, Bondar, N. P., Antontseva, E. V., Merkulova, T. I., Kolchanov, N. A.

“…We describe development and application of the new SNP-MED modular software system, designed to examine the influence of single-nucleotide polymorphisms (SNPs)…”
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THE SNP-MED SYSTEM FOR ANALYSIS OF THE EFFECT OF SINGLE-NUCLEOTIDE POLYMORPHISMS ON THE FUNCTION OF GENES ASSOCIATED WITH SOCIALLY SIGNIFICANT DISEASES by N. L. Podkolodnyy, D. A. Afonnikov, Yu. Yu. Vaskin, L. O. Bryzgalov, V. A. Ivanisenko, P. S. Demenkov, M. P. Ponomarenko, D. A. Rasskazov, K. V. Gunbin, I. V. Protsyuk, I. Yu. Shutov, P. N. Leontyev, M. Yu. Fursov, N. P. Bondar, E. V. Antontseva, T. I. Merkulova, N. A. Kolchanov

“…This paper describes the SNP-MED modular computer-based information system for estimation of the influence of single nucleotide polymorphisms (SNPs) on the…”
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Species-specific effects of the hepatocarcinogens 3′-methyl-4-dimethyl-aminoazobenzene and ortho-aminoazotoluene in mouse and rat liver by Merkulova, Tatyana I., Kropachev, Konstantin Y., Timofeeva, Olga A., Vasiliev, Gennady V., Levashova, Zoia B., Ilnitskaya, Svetlana I., Kobzev, Victor F., Pakharukova, Maria Yu, Bryzgalov, Leonid O., Kaledin, Vasily I.

“…The effects of rat‐specific hepatocarcinogen 3′‐methyl‐4‐dimethylaminoazobenzene (3′‐MeDAB), mouse‐specific hepatocarcinogen ortho‐aminoazotoluene (OAT),…”
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