Search Results - "Bryson, J"
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Semantics derived automatically from language corpora contain human-like biases
Published in Science (American Association for the Advancement of Science) (14-04-2017)“…Machine learning is a means to derive artificial intelligence by discovering patterns in existing data. Here, we show that applying machine learning to…”
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Multi-stakeholder Engagement for the Sustainable Development Goals: Introduction to the Special Issue
Published in Journal of business ethics (01-11-2022)“…The world is not on track to achieve Agenda 2030—the approach chosen in 2015 by all UN member states to engage multiple stakeholders for the common goal of…”
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3
The cholesterol depleting agent, (2-Hydroxypropyl)-ß-cyclodextrin, does not affect disease progression in SOD1G93A mice
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (25-07-2023)“…Objective: Previously, we demonstrated that Amyloid Precursor Protein (APP) contributes to pathology in the SOD1 G93A mouse model of ALS and that genetic…”
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4
Optical Control of Muscle Function by Transplantation of Stem Cell–Derived Motor Neurons in Mice
Published in Science (American Association for the Advancement of Science) (04-04-2014)“…Damage to the central nervous system caused by traumatic injury or neurological disorders can lead to permanent loss of voluntary motor function and muscle…”
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Linking life‐history theory and metabolic theory explains the offspring size‐temperature relationship
Published in Ecology letters (01-03-2019)“…Temperature often affects maternal investment in offspring. Across and within species, mothers in colder environments generally produce larger offspring than…”
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6
An optogenetic cell therapy to restore control of target muscles in an aggressive mouse model of amyotrophic lateral sclerosis
Published in eLife (18-01-2024)“…Breakdown of neuromuscular junctions (NMJs) is an early pathological hallmark of amyotrophic lateral sclerosis (ALS) that blocks neuromuscular transmission,…”
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7
The role of ADHD associated genes in neurodevelopment
Published in Developmental biology (15-06-2018)“…Attention deficit hyperactivity disorder (ADHD) is a highly heritable neurodevelopmental disorder of childhood. It is primarily characterised by high levels of…”
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Kinesthetic Feedback for Understanding Program Execution
Published in Sensors (Basel, Switzerland) (29-05-2023)“…To better prepare future generations, knowledge about computers and programming are one of the many skills that are part of almost all Science, Technology,…”
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Small Amounts of Sub-Visible Aggregates Enhance the Immunogenic Potential of Monoclonal Antibody Therapeutics
Published in Pharmaceutical research (01-04-2015)“…Purpose Determine the effect of minute quantities of sub-visible aggregates on the in vitro immunogenicity of clinically relevant protein therapeutics. Methods…”
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10
Genetic compensation triggered by actin mutation prevents the muscle damage caused by loss of actin protein
Published in PLoS genetics (08-02-2018)“…The lack of a mutant phenotype in homozygous mutant individuals' due to compensatory gene expression triggered upstream of protein function has been identified…”
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11
Sample drift correction following 4D confocal time-lapse imaging
Published in Journal of visualized experiments (12-04-2014)“…The generation of four-dimensional (4D) confocal datasets; consisting of 3D image sequences over time; provides an excellent methodology to capture cellular…”
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12
Restoring motor function using optogenetics and neural engraftment
Published in Current opinion in biotechnology (01-08-2016)“…Graphical abstract Schematic representation of a combinatorial closed-loop system to restore functionality to paralysed muscles, enabling control of specific…”
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13
Constraints on the Distances and Timescales of Solid Migration in the Early Solar System from Meteorite Magnetism
Published in The Astrophysical journal (01-06-2020)“…The migrations of solid objects throughout the solar system are thought to have played key roles in disk evolution and planet formation. However, our…”
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Evidence for Asteroid Scattering and Distal Solar System Solids From Meteorite Paleomagnetism
Published in The Astrophysical journal (01-04-2020)“…Asteroid-sized bodies are predicted to have been scattered throughout the solar system following gravitational interactions with the giant planets. This…”
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15
CRIMP: a CRISPR/Cas9 insertional mutagenesis protocol and toolkit
Published in Nature communications (12-06-2024)“…Site-directed insertion is a powerful approach for generating mutant alleles, but low efficiency and the need for customisation for each target has limited its…”
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FLNC myofibrillar myopathy results from impaired autophagy and protein insufficiency
Published in Human molecular genetics (01-06-2016)“…Myofibrillar myopathy is a progressive muscle disease characterized by the disintegration of muscle fibers and formation of protein aggregates. Causative…”
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Comparative Analysis of Different Inbred Chicken Lines Highlights How a Hereditary Inflammatory State Affects Susceptibility to Avian Influenza Virus
Published in Viruses (21-02-2023)“…Evidence suggests that susceptibility to avian influenza A virus in chickens is influenced by host genetics, but the mechanisms are poorly understood. A…”
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Activated CREB Is Sufficient to Overcome Inhibitors in Myelin and Promote Spinal Axon Regeneration In Vivo
Published in Neuron (Cambridge, Mass.) (18-11-2004)“…Inhibitors in myelin play a major role in preventing spontaneous axonal regeneration after CNS injury. Elevation of cAMP overcomes this inhibition, in a…”
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Neurocognition, Social Cognition, Perceived Social Discomfort, and Vocational Outcomes in Schizophrenia
Published in Schizophrenia bulletin (01-07-2009)“…Social cognition has been suggested to be an important mediating variable in the relationship between neurocognition and functional outcome. The present study…”
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Nidogens are therapeutic targets for the prevention of tetanus
Published in Science (American Association for the Advancement of Science) (28-11-2014)“…Tetanus neurotoxin (TeNT) is among the most poisonous substances on Earth and a major cause of neonatal death in nonvaccinated areas. TeNT targets the…”
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