Search Results - "Bryksin, Anton V"
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Overlap extension PCR cloning: a simple and reliable way to create recombinant plasmids
Published in BioTechniques (01-06-2010)“…Here we describe a straightforward, efficient, and reliable way to clone an insert of choice into a plasmid of choice without restriction endonucleases or T4…”
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2
High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
Published in Proceedings of the National Academy of Sciences - PNAS (16-10-2018)“…Dysfunctional endothelium causes more disease than any other cell type. Systemically administered RNA delivery to nonliver tissues remains challenging, in…”
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3
A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation
Published in Nano letters (14-03-2018)“…Endothelial cells and macrophages play active roles in disease and as a result are important targets for nucleic acid therapies. While thousands of chemically…”
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Rational design of a plasmid origin that replicates efficiently in both gram-positive and gram-negative bacteria
Published in PloS one (08-10-2010)“…Most plasmids replicate only within a particular genus or family. Here we describe an engineered high copy number expression vector, pBAV1K-T5, that produces…”
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5
Bacteria‐Based Materials for Stem Cell Engineering
Published in Advanced materials (Weinheim) (01-10-2018)“…Materials can be engineered to deliver specific biological cues that control stem cell growth and differentiation. However, current materials are still limited…”
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6
Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction
Published in The Journal of cell biology (12-10-2015)“…Progressive fibrosis is characterized by excessive deposition of extracellular matrix (ECM), resulting in gross alterations in tissue mechanics. Changes in…”
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7
Ribonucleotide incorporation in yeast genomic DNA shows preference for cytosine and guanosine preceded by deoxyadenosine
Published in Nature communications (15-05-2020)“…Despite the abundance of ribonucleoside monophosphates (rNMPs) in DNA, sites of rNMP incorporation remain poorly characterized. Here, by using ribose-seq and…”
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8
Validation of Saliva as the Clinical Specimen Type for a University-Wide COVID-19 Surveillance Program
Published in Viruses (21-09-2024)“…At the beginning of the COVID-19 pandemic, the Georgia Institute of Technology made the decision to keep the university doors open for on-campus attendance. To…”
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9
Escherichia coli deletion mutants illuminate trade-offs between growth rate and flux through a foreign anabolic pathway
Published in PloS one (04-02-2014)“…Metabolic engineers strive to improve the production yields of microbial fermentations, sometimes by mutating the genomes of production strains. Some mutations…”
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10
Analyzing 2000 in Vivo Drug Delivery Data Points Reveals Cholesterol Structure Impacts Nanoparticle Delivery
Published in ACS nano (28-08-2018)“…Lipid nanoparticles (LNPs) are formulated using unmodified cholesterol. However, cholesterol is naturally esterified and oxidized in vivo, and these…”
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11
Heterologous Prime-Boost with Immunologically Orthogonal Protein Nanoparticles for Peptide Immunofocusing
Published in ACS nano (23-07-2024)“…Protein nanoparticles are effective platforms for antigen presentation and targeting effector immune cells in vaccine development. Encapsulins are a class of…”
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12
Modifying a Commonly Expressed Endocytic Receptor Retargets Nanoparticles in Vivo
Published in Nano letters (12-12-2018)“…Nanoparticles are often targeted to receptors expressed on specific cells, but few receptors are (i) highly expressed on one cell type and (ii) involved in…”
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Borrelia burgdorferi rel Is Responsible for Generation of Guanosine-3'-Diphosphate-5'-Triphosphate and Growth Control
Published in Infection and Immunity (01-08-2005)“…The global transcriptional regulator (p)ppGpp (guanosine-3'-diphosphate-5'-triphosphate and guanosine-3',5'-bisphosphate, collectively) produced by the relA…”
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14
Borrelia burgdorferi Binds to, Invades, and Colonizes Native Type I Collagen Lattices
Published in Infection and Immunity (01-06-2004)“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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15
A blueprint for academic laboratories to produce SARS-CoV-2 quantitative RT-PCR test kits
Published in The Journal of biological chemistry (13-11-2020)“…Widespread testing for the presence of the novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals remains vital for…”
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16
Learning from nature – Novel synthetic biology approaches for biomaterial design
Published in Acta biomaterialia (01-04-2014)“…[Display omitted] Many biomaterials constructed today are complex chemical structures that incorporate biologically active components derived from nature, but…”
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17
Construction of long DNA molecules using long PCR‐based fusion of several fragments simultaneously
Published in Nucleic acids research (01-01-2004)“…A procedure for precise assembly of linear DNA constructs as long as 20 kb is proposed. The method, which we call long multiple fusion, has been used to…”
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Borrelia burgdorferi BmpA, BmpB, and BmpD proteins are expressed in human infection and contribute to P39 immunoblot reactivity in patients with Lyme disease
Published in Clinical and Diagnostic Laboratory Immunology (01-08-2005)“…The Bmp proteins are a paralogous family of chromosomally encoded Borrelia burgdorferi lipoproteins. They have similar predicted immunogenicities and similar…”
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Localization of BmpA on the Exposed Outer Membrane of Borrelia burgdorferi by Monospecific Anti-Recombinant BmpA Rabbit Antibodies
Published in Infection and Immunity (01-04-2004)“…RETRACTION ( vol. 76 , p. 4792 ) Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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20
Functional analysis of Borrelia burgdorferi uvrA in DNA damage protection
Published in FEMS microbiology letters (01-04-2011)“…Abstract Bacterial pathogens face constant challenges from DNA-damaging agents generated by host phagocytes. Although Borrelia burgdorferi appears to have much…”
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