Search Results - "Bryke, Christine R."

Chromothriptic Cure of WHIM Syndrome by McDermott, David H., Gao, Ji-Liang, Liu, Qian, Siwicki, Marie, Martens, Craig, Jacobs, Paejonette, Velez, Daniel, Yim, Erin, Bryke, Christine R., Hsu, Nancy, Dai, Zunyan, Marquesen, Martha M., Stregevsky, Elina, Kwatemaa, Nana, Theobald, Narda, Long Priel, Debra A., Pittaluga, Stefania, Raffeld, Mark A., Calvo, Katherine R., Maric, Irina, Desmond, Ronan, Holmes, Kevin L., Kuhns, Douglas B., Balabanian, Karl, Bachelerie, Françoise, Porcella, Stephen F., Malech, Harry L., Murphy, Philip M.

“…Chromothripsis is a catastrophic cellular event recently described in cancer in which chromosomes undergo massive deletion and rearrangement. Here, we report a…”
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Incidence and patterns of ALK FISH abnormalities seen in a large unselected series of lung carcinomas by Dai, Zunyan, Kelly, Joann C, Meloni-Ehrig, Aurelia, Slovak, Marilyn L, Boles, Debra, Christacos, Nicole C, Bryke, Christine R, Schonberg, Steven A, Otani-Rosa, Jennifer, Pan, Qiulu, Ho, Albert K, Sanders, Heather R, Zhang, Zhong J, Jones, Dan, Mowrey, Philip N

“…Anaplastic lymphoma receptor tyrosine kinase (ALK) gene rearrangements have been reported in 2-13% of patients with non-small cell lung cancer (NSCLC)…”
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Distinct Missense Mutations of the FGFR3 Lys650 Codon Modulate Receptor Kinase Activation and the Severity of the Skeletal Dysplasia Phenotype by Bellus, Gary A., Spector, Elaine B., Speiser, Phyllis W., Weaver, Christine A., Garber, Anthony T., Bryke, Christine R., Israel, Jamie, Rosengren, Sally S., Webster, Melanie K., Donoghue, Daniel J., Francomano, Clair A.

“…The fibroblast growth factor–receptor 3 (FGFR3) Lys650 codon is located within a critical region of the tyrosine kinase–domain activation loop. Two missense…”
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Challenging cases of follicular lymphoma diagnosed by core needle biopsy incorporating proliferation index and cytogenetics by Hirt, Christian K., Bryke, Christine R., Jassim, Sarmad H.

“…•Small core needle biopsies of enlarged lymph nodes may lead to diagnostic challenges in accurately grading follicular lymphoma and may not be representative…”
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Characteristics of myeloproliferative neoplasms in patients exposed to ionizing radiation following the Chernobyl nuclear accident by Poluben, Larysa, Puligandla, Maneka, Neuberg, Donna, Bryke, Christine R., Hsu, Yahsuan, Shumeiko, Oleksandr, Yuan, Xin, Voznesensky, Olga, Pihan, German, Adam, Miriam, Fraenkel, Ernest, Rasnic, Roni, Linial, Michal, Klymenko, Sergiy, Balk, Steven P., Fraenkel, Paula G.

“…Myeloproliferative neoplasms (MPNs) driver mutations are usually found in JAK2, MPL, and CALR genes; however, 10%‐15% of cases are triple negative (TN). A…”
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EBV‐positive, HHV8‐negative large B‐cell lymphoma with an unusual germinotropic growth pattern in an immunocompetent patient by Asakrah, Saja K., Bhargava, Parul, Bryke, Christine R.

“…Key Clinical Message Clinicopathologic and cytogenetic findings of an unusual EBV+ve, HHV8−ve germinotropic lymphoma, with a nongerminal center immunophenotype…”
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EBV ‐positive, HHV 8‐negative large B‐cell lymphoma with an unusual germinotropic growth pattern in an immunocompetent patient by Asakrah, Saja K., Bhargava, Parul, Bryke, Christine R.

“…Key Clinical Message Clinicopathologic and cytogenetic findings of an unusual EBV +ve, HHV 8−ve germinotropic lymphoma, with a nongerminal center…”
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Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAFV600E by Antonello, Zeus A., Hsu, Nancy, Bhasin, Manoj, Roti, Giovanni, Joshi, Mukta, Van Hummelen, Paul, Ye, Emily, Lo, Agnes S., Karumanchi, S. Ananth, Bryke, Christine R., Nucera, Carmelo

“…PURPOSEPapillary thyroid carcinoma (PTC) is the most frequent endocrine tumor. BRAFV600E represents the PTC hallmark and is targeted with selective inhibitors…”
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WHIM Syndrome Cured by Chromothripsis by Bryke, Christine R, McDermott, David H, Gao, Ji-Liang, Liu, Qian, Siwicki, Marie, Martens, Craig, Jacobs, Paejonette, Velez, Daniel, Yim, Erin, Hsu, Nancy, Dai, Zunyan, Marquesen, Martha M, Stregevsky, Elina, Kwatemaa, Nana, Theobald, Narda, Long Priel, Debra A, Pittaluga, Stefania, Raffeld, Mark A, Calvo, Katherine R, Maric, Irina, Desmond, Ronan, Holmes, Kevin L, Kuhns, Douglas B, Balabanian, Karl, Bachelerie, Françoise, Porcella, Stephen F, Malech, Harry L, Murphy, Philip M

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Marfan syndrome type II: there is more to Marfan syndrome than fibrillin 1 by Zangwill, Steven D, Brown, Matthew D, Bryke, Christine R, Cava, Joseph R, Segura, Annette D

“…Marfan syndrome is a well-described autosomal dominant syndrome with widely variable clinical manifestations. Cardiovascular complications include mitral valve…”
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Abstract 3093: Genomic characteristics of myeloproliferative neoplasms in patients exposed to ionizing radiation following the Chernobyl nuclear accident by Poluben, Larysa, Puligandla, Maneka, Neuberg, Donna, Bryke, Christine R., Hsu, Nancy, Klymenko, Sergiy, Mishcheniuk, Olga, Shumeiko, Oleksandr, Balk, Steven, Yuan, Xin, Voznesensky, Olga, Pihan, German, Adam, Miriam, Fraenkel, Ernest, Fraenkel, Paula G.

“…Abstract Philadelphia-chromosome negative chronic myeloproliferative neoplasms (MPNs) are a unique group of hematological malignancies including Polycytemia…”
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Genomic Characteristics of Myeloproliferative Neoplasms in Patients Exposed to Ionizing Radiation following the Chernobyl Nuclear Accident by Poluben, Larysa, Puligandla, Maneka, Neuberg, Donna, Bryke, Christine R., Hsu, Yahsuan, Shumeiko, Oleksandr, Yuan, Xin, Voznesensky, Olga, Pihan, German, Adam, Miriam, Fraenkel, Ernest, Rasnic, Roni, Linial, Michal, Klymenko, Sergiy, Balk, Steven P., Fraenkel, Paula G.

“…Myeloproliferative neoplasms (MPNs) driver mutations are usually found in JAK2 , MPL and CALR genes, however, 10–15% of cases are triple negative (TN). A…”
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Abstract B08: New Abelson interactor-1(Abi-1)-driven mechanism of acquired drug resistance by Chorzalska, Anna, Salloum, Ibrahem, Marjon, Philip, Treaba, Diana, Schorl, Christoph, John, Morgan, Bryke, Christine R., Reagan, John, Winer, Eric, Olszewski, Adam J., Dubielecka, Patrycja M.

“…Abstract In hematological malignancies, quiescent leukemic stem cells are responsible for persistence of minimal residual disease and relapse. We have recently…”
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Low expression of Abelson interactor-1 is linked to acquired drug resistance in Bcr-Abl-induced leukemia by Chorzalska, A, Salloum, I, Shafqat, H, Khan, S, Marjon, P, Treaba, D, Schorl, C, Morgan, J, Bryke, C R, Falanga, V, Zhao, T C, Reagan, J, Winer, E, Olszewski, A J, Al-Homsi, A S, Kouttab, N, Dubielecka, P M

“…The basis for persistence of leukemic stem cells in the bone marrow microenvironment remains poorly understood. We present evidence that signaling cross-talk…”
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Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAF V600E by Antonello, Zeus A, Hsu, Nancy, Bhasin, Manoj, Roti, Giovanni, Joshi, Mukta, Van Hummelen, Paul, Ye, Emily, Lo, Agnes S, Karumanchi, S Ananth, Bryke, Christine R, Nucera, Carmelo

“…Papillary thyroid carcinoma (PTC) is the most frequent endocrine tumor. BRAF represents the PTC hallmark and is targeted with selective inhibitors (e.g…”
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Solitary Rectal Ulcer Syndrome in a Teenaged Boy by Sondheimer, Judith M., Slagle, Terri A., Bryke, Christine R., Hill, Rolla B.

“…Since the original description of solitary rectal ulcer by Cruveilheir in 1830, about 250 cases have been reported (1). The condition most frequently presents…”
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Desbuquois syndrome: clinical, radiographic, and morphologic characterization by Shohat, M, Lachman, R, Gruber, H E, Hsia, Y E, Golbus, M S, Witt, D R, Bodell, A, Bryke, C R, Hogge, W A, Rimoin, D L

“…To further characterize the clinical, radiographic and chondro-osseous morphologic changes in the Desbuquois syndrome, 7 patients from three sibships are…”
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EBV-positive, HHV8-negative large B-cell lymphoma with an unusual germinotropic growth pattern in an immunocompetent patient by Asakrah, Saja K, Bhargava, Parul, Bryke, Christine R

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Phenotypic, cytogenetic, and molecular studies of three patients with constitutional deletions of chromosome 5 in the region of the gene for familial adenomatous polyposis by LINDGREN, V, BRYKE, C. R, OZCELIK, T, YANG-FENG, T. L, FRANCKE, U

“…We have studied three patients, one with extensive polyposis of the colon, who have constitutional interstitial deletions of the long arm of chromosome 5…”
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Cytogenetic and molecular characterization of marker chromosomes in patients with mosaic 45,X karyotypes by LINDGREN, V, CHIH-PING CHEN, BRYKE, C. R, LICHTER, P, PAGE, D. C, YANG-FENG, T. L

“…Cytogenetic and molecular techniques were employed to determine the origin of marker chromosomes in five patients with mosaic 45,X karyotypes. The markers were…”
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