Search Results - "Bryce, Steven D"
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Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions
Published in Genome biology (20-05-2008)“…The tumor-initiating capacity of many cancers is considered to reside in a small subpopulation of cells (cancer stem cells). We have previously shown that rare…”
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A Mortality Gene(s) for the Human Adenocarcinoma Line HeLa Maps to a 130-kb Region of Human Chromosome 4q22-q23
Published in Neoplasia (New York, N.Y.) (01-11-2002)“…Human chromosome 4 was previously shown to elicit features of senescence when introduced into cell lines that map to complementation group B for senescence,…”
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Functional evidence for a squamous cell carcinoma mortality gene(s) on human chromosome 4
Published in Oncogene (01-08-2002)“…Squamous cell carcinoma (SCC) immortality is associated with p53 and INK4A dysfunction, high levels of telomerase and loss of heterozygosity (LOH) of other…”
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Genetic and functional analyses exclude mortality factor 4 (MORF4) as a keratinocyte senescence gene
Published in Cancer research (Chicago, Ill.) (01-05-1999)“…Approximately 50% of immortal human keratinocyte lines show loss of heterozygosity of chromosome region 4q33-q34, and the reintroduction of chromosome 4 into…”
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Refined Genetic Mapping of the Darier Locus to a <1-cM Region of Chromosome 12q24.1, and Construction of a Complete, High-Resolution P1 Artificial Chromosome/Bacterial Artificial Chromosome Contig of the Critical Region
Published in American journal of human genetics (01-04-1998)“…Darier disease (DD) (MIM 124200) is an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and by abnormal…”
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Linkage analyses in British pedigrees suggest a single locus for Darier disease and narrow the location to the interval between D12S105 and D12S129
Published in Genomics (San Diego, Calif.) (15-11-1994)“…Darier disease is a dominantly inherited skin disorder in which there appears to be abnormal adhesion between keratinocytes. We and others have shown that the…”
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