Search Results - "Bryant, Annamarie T"

IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells by Remsing Rix, Lily L, Sumi, Natalia J, Hu, Qianqian, Desai, Bina, Bryant, Annamarie T, Li, Xueli, Welsh, Eric A, Fang, Bin, Kinose, Fumi, Kuenzi, Brent M, Chen, Y Ann, Antonia, Scott J, Lovly, Christine M, Koomen, John M, Haura, Eric B, Marusyk, Andriy, Rix, Uwe

“…Cancer-associated fibroblasts (CAFs) in the tumor microenvironment are often linked to drug resistance. Here, we found that coculture with CAFs or culture in…”
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Overexpression of the microtubule-binding protein CLIP-170 induces a +TIP network superstructure consistent with a biomolecular condensate by Wu, Yueh-Fu O, Bryant, Annamarie T, Nelson, Nora T, Madey, Alexander G, Fernandes, Gail F, Goodson, Holly V

“…Proper regulation of microtubule (MT) dynamics is critical for cellular processes including cell division and intracellular transport. Plus-end tracking…”
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Dabrafenib inhibits the growth of BRAF‐WT cancers through CDK16 and NEK9 inhibition by Phadke, Manali, Remsing Rix, Lily L., Smalley, Inna, Bryant, Annamarie T., Luo, Yunting, Lawrence, Harshani R., Schaible, Braydon J., Chen, Yian A., Rix, Uwe, Smalley, Keiran S. M.

“…Although the BRAF inhibitors dabrafenib and vemurafenib have both proven successful against BRAF‐mutant melanoma, there seem to be differences in their…”
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Polypharmacology-based ceritinib repurposing using integrated functional proteomics by Kuenzi, Brent M, Remsing Rix, Lily L, Stewart, Paul A, Fang, Bin, Kinose, Fumi, Bryant, Annamarie T, Boyle, Theresa A, Koomen, John M, Haura, Eric B, Rix, Uwe

“…A systems chemical biology approach to characterize beneficial off-target effects revealed a polypharmacology mechanism for the multikinase inhibitor ceritinib…”
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The CLIP-170 N-terminal domain binds directly to both F-actin and microtubules in a mutually exclusive manner by Wu, Yueh-Fu O., Miller, Rachel A., Alberico, Emily O., Huang, Yaobing A.P., Bryant, Annamarie T., Nelson, Nora T., Jonasson, Erin M., Goodson, Holly V.

“…The cooperation between the actin and microtubule (MT) cytoskeletons is important for cellular processes such as cell migration and muscle cell development…”
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Abstract C110: Cancer associated fibroblast-derived IGF-binding proteins augment osimertinib activity in EGFR-mutant NSCLC cells by Rix, Lily L. Remsing, Sumi, Natalia J., Bryant, Annamarie T., Li, Xueli, Welsh, Eric A., Fang, Bin, Kuenzi, Brent M., Antonia, Scott J., Marusyk, Andriy, Lovly, Christine M., Koomen, John M., Haura, Eric B., Rix, Uwe

“…Abstract Background: Cancer associated fibroblasts (CAFs) are an integral part of the tumor microenvironment, which is implicated in tumor growth, metastasis…”
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Overexpression of the microtubule-binding protein CLIP-170 induces a +TIP network superstructure consistent with a biomolecular condensate by Yueh-Fu O Wu, Annamarie T Bryant, Nora T Nelson, Alexander G Madey, Gail F Fernandes, Holly V Goodson

“…Proper regulation of microtubule (MT) dynamics is critical for cellular processes including cell division and intracellular transport. Plus-end tracking…”
Get full text