Search Results - "Bryan de la Peña, June"
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involvement of magnoflorine in the sedative and anxiolytic effects of Sinomeni Caulis et Rhizoma in mice
Published in Journal of natural medicines (01-10-2013)“…The present study seeks to evaluate the sedative and anxiolytic effects of the 70 % ethanol extract of Sinomeni Caulis et Rhizoma (SR). The extract was orally…”
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Rearing in an enriched environment attenuated hyperactivity and inattention in the Spontaneously Hypertensive Rats, an animal model of Attention-Deficit Hyperactivity Disorder
Published in Physiology & behavior (01-03-2016)“…Abstract Attention-deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder, characterized by symptoms of hyperactivity, inattention,…”
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3
RNA control in pain: Blame it on the messenger
Published in Wiley interdisciplinary reviews. RNA (01-11-2019)“…mRNA function is meticulously controlled. We provide an overview of the integral role that posttranscriptional controls play in the perception of painful…”
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4
Conditioned place preference and self-administration induced by nicotine in adolescent and adult rats
Published in Biomolecules & therapeutics (01-09-2014)“…Nicotine addiction is a worldwide problem. However, previous studies characterizing the rewarding and reinforcing effects of nicotine in animal models have…”
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A peptide encoded within a 5′ untranslated region promotes pain sensitization in mice
Published in Pain (Amsterdam) (01-06-2021)“…Translational regulation permeates neuronal function. Nociceptors are sensory neurons responsible for the detection of harmful stimuli. Changes in their…”
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The ethanol extract of Cirsium japonicum increased chloride ion influx through stimulating GABAA receptor in human neuroblastoma cells and exhibited anxiolytic-like effects in mice
Published in Drug Discoveries & Therapeutics (2013)“…The aim of the present study was to evaluate the anxiolytic effects of the ethanol extract of Cirsium japonicum (CJ) in mice. The extract was orally…”
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A role for translational regulation by S6 kinase and a downstream target in inflammatory pain
Published in British journal of pharmacology (01-12-2021)“…Background and Purpose Translational controls pervade neurobiology. Nociceptors play an integral role in the detection and propagation of pain signals…”
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The Abuse Potential of α-Piperidinopropiophenone (PIPP) and α-Piperidinopentiothiophenone (PIVT), Two New Synthetic Cathinones with Piperidine Ring Substituent
Published in Biomolecules & therapeutics (01-03-2017)“…A diversity of synthetic cathinones has flooded the recreational drug marketplace worldwide. This variety is often a response to legal control actions for one…”
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A Highly Selective MNK Inhibitor Rescues Deficits Associated with Fragile X Syndrome in Mice
Published in Neurotherapeutics (01-01-2021)“…Fragile X syndrome (FXS) is the most common inherited source of intellectual disability in humans. FXS is caused by mutations that trigger epigenetic silencing…”
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The circadian gene, Per2, influences methamphetamine sensitization and reward through the dopaminergic system in the striatum of mice
Published in Addiction biology (01-09-2019)“…Drug addiction is a chronic and relapsing brain disorder, influenced by complex interactions between endogenous and exogenous factors. Per2, a circadian gene,…”
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Neurobiological Functions of the Period Circadian Clock 2 Gene, Per2
Published in Biomolecules & therapeutics (01-07-2018)“…Most organisms have adapted to a circadian rhythm that follows a roughly 24-hour cycle, which is modulated by both internal (clock-related genes) and external…”
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Exploring the Validity of Proposed Transgenic Animal Models of Attention-Deficit Hyperactivity Disorder (ADHD)
Published in Molecular neurobiology (01-05-2018)“…Attention-deficit/hyperactivity disorder (ADHD) is a common, behavioral, and heterogeneous neurodevelopmental condition characterized by hyperactivity,…”
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Common prefrontal cortical gene expression profiles between adolescent SHR/NCrl and WKY/NCrl rats which showed inattention behavior
Published in Behavioural brain research (15-09-2015)“…•We describe novel genes associated with inattention in SHR/NCrl and WKY/NCrl.•These are genes involved in transcription, synapse transmission, immune system,…”
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Rewarding and reinforcing effects of the NMDA receptor antagonist–benzodiazepine combination, zoletil®: Difference between acute and repeated exposure
Published in Behavioural brain research (01-08-2012)“…► Tiletamine is rewarding and reinforcing in rats. ► Zolazepam induced place preference but not self-administration. ► Acute zoletil treatment produced neither…”
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Conserved Expression of Nav1.7 and Nav1.8 Contribute to the Spontaneous and Thermally Evoked Excitability in IL-6 and NGF-Sensitized Adult Dorsal Root Ganglion Neurons In Vitro
Published in Bioengineering (Basel) (16-05-2020)“…Sensory neurons respond to noxious stimuli by relaying information from the periphery to the central nervous system via action potentials driven by…”
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The psychopharmacological activities of Vietnamese ginseng in mice: characterization of its psychomotor, sedative–hypnotic, antistress, anxiolytic, and cognitive effects
Published in Journal of ginseng research (01-04-2017)“…Panax vietnamensis Ha et Grushv. or Vietnamese ginseng (VG) is a recently discovered ginseng species. Studies on its chemical constituents have shown that VG…”
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Pre-exposure to ethanol, but not to caffeine and nicotine, induced place preference and self-administration of the NMDA receptor antagonist-benzodiazepine combination, Zoletil
Published in Pharmacology, biochemistry and behavior (01-09-2013)“…Zoletil® is an equal amount combination of the NMDA receptor antagonist, tiletamine, and the benzodiazepine, zolazepam, usually used as a veterinary…”
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Assessment of the Abuse Liability of Synthetic Cannabinoid Agonists JWH-030, JWH-175, and JWH-176
Published in Biomolecules & therapeutics (01-11-2015)“…The emergence and use of synthetic cannabinoids have greatly increased in recent years. These substances are easily dispensed over the internet and on the…”
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Luteolin mediates the antidepressant-like effects of Cirsium japonicum in mice, possibly through modulation of the GABAA receptor
Published in Archives of pharmacal research (01-02-2014)“…Cirsium japonicum (CJ) has been shown to possess antidepressant-like properties. In the present study, we sought to identify which constituent of CJ might be…”
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Protection Against Electroshock- and Pentylenetetrazol-induced Seizures by the Water Extract of Rehmannia glutinous can be Mediated through GABA Receptor-chloride Channel Complexes
Published in Natural product sciences (2017)“…Epilepsy is a brain disorder that affects millions of people worldwide. It is characterized by recurrent and unpredictable seizures that are usually controlled…”
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