Search Results - "Bryan, Nicole B"
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1
An NLRP7-Containing Inflammasome Mediates Recognition of Microbial Lipopeptides in Human Macrophages
Published in Immunity (Cambridge, Mass.) (23-03-2012)“…Cytosolic pathogen- and damage-associated molecular patterns are sensed by pattern recognition receptors, including members of the nucleotide-binding domain…”
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Journal Article -
2
Activation of Inflammasomes Requires Intracellular Redistribution of the Apoptotic Speck-Like Protein Containing a Caspase Recruitment Domain
Published in The Journal of immunology (1950) (01-03-2009)“…Activation of caspase 1 is essential for the maturation and release of IL-1beta and IL-18 and occurs in multiprotein complexes, referred to as inflammasomes…”
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Journal Article -
3
Upregulation of miRNA-4776 in Influenza Virus Infected Bronchial Epithelial Cells Is Associated with Downregulation of NFKBIB and Increased Viral Survival
Published in Viruses (27-04-2017)“…Influenza A virus (IAV) infection remains a significant cause of morbidity and mortality worldwide. One key transcription factor that is activated upon IAV…”
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Journal Article -
4
Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes
Published in Journal of inflammation (London, England) (18-05-2010)“…The apoptotic speck-like protein containing a caspase recruitment domain (ASC) is the essential adaptor protein for caspase 1 mediated interleukin (IL)-1beta…”
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Journal Article -
5
Cellular Pyrin Domain-Only Protein 2 Is a Candidate Regulator of Inflammasome Activation
Published in Infection and Immunity (01-03-2007)“…Pyrin domain (PYD) proteins have recently emerged as important signaling molecules involved in the development of innate immunity against intracellular…”
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Journal Article -
6
A Shope Fibroma virus PYRIN-only protein modulates the host immune response
Published in Virus genes (01-12-2007)“…PYRIN domain (PYD) proteins have recently emerged as important signaling molecules involved in the development of innate immunity to intracellular pathogens…”
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Journal Article -
7
Shope Fibroma virus PYRIN-only protein modulates the host immune response
Published in Virus genes (01-12-2007)“…PYRIN domain (PYD) proteins have recently emerged as important signaling molecules involved in the development of innate immunity to intracellular pathogens…”
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Journal Article -
8
Pathogen-induced activation of inflammasomes requires intracellular redistribution of the apoptosis associated speck-like protein containing a caspase recruitment domain (ASC) (135.70)
Published in The Journal of immunology (1950) (01-04-2009)“…Activation of caspase-1, which is necessary for the maturation and secretion of the pro-inflammatory cytokines IL-1β and IL-18, occurs upon assembly of…”
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Journal Article -
9
Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain (ASC)1
Published in The Journal of immunology (1950) (01-03-2009)“…Activation of caspase-1 is essential for the maturation and release of interleukin (IL)-1β and IL-18, and occurs in multi-protein complexes, referred to as…”
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Journal Article -
10
Subcellular distribution of apoptosis associated speck-like protein mediates inflammasome assembly: A novel mechanism in the regulation of interleukin-1beta release
Published 01-01-2011“…Inflammation is an essential component of the innate immune defense against pathogens. The process of inflammation is mediated by the rapid release of…”
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Dissertation -
11
Subcellular distribution of apoptosis associated speck-like protein mediates inflammasome assembly: A novel mechanism in the regulation of interleukin-1beta release
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Dissertation