Search Results - "Bruyns, Eddy"

The Transmembrane Adapter Protein SIT Regulates Thymic Development and Peripheral T-Cell Functions by Simeoni, Luca, Posevitz, Vilmos, Kölsch, Uwe, Meinert, Ines, Bruyns, Eddy, Pfeffer, Klaus, Reinhold, Dirk, Schraven, Burkhart

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Normal T-Cell Development and Immune Functions in TRIM-Deficient Mice by Kölsch, Uwe, Arndt, Börge, Reinhold, Dirk, Lindquist, Jonathan A., Jüling, Nicole, Kliche, Stefanie, Pfeffer, Klaus, Bruyns, Eddy, Schraven, Burkhart, Simeoni, Luca

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Identification of the Sites of Interaction between Lymphocyte Phosphatase-associated Phosphoprotein (LPAP) and CD45 (∗) by Bruyns, Eddy, Hendricks-Taylor, L. Ranee, Meuer, Stefan, Koretzky, Gary A., Schraven, Burkhart

“…Human lymphocyte phosphatase-associated phosphoprotein (LPAP) is a phosphoprotein of unknown function that noncovalently associates with CD45 in lymphocytes…”
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Molecular Cloning of SKAP55, a Novel Protein That Associates with the Protein Tyrosine Kinase p59 fyn in Human T-lymphocytes by Marie-Cardine, Anne, Bruyns, Eddy, Eckerskorn, Christoph, Kirchgessner, Henning, Meuer, Stefan C., Schraven, Burkhart

“…In human T-lymphocytes the Src family protein tyrosine kinase p59 fyn associates with three phosphoproteins of 43, 55, and 85 kDa (pp43, pp55, and pp85)…”
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Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation by Brdicka, T, Pavlistová, D, Leo, A, Bruyns, E, Korínek, V, Angelisová, P, Scherer, J, Shevchenko, A, Hilgert, I, Cerný, J, Drbal, K, Kuramitsu, Y, Kornacker, B, Horejsí, V, Schraven, B

“…According to a recently proposed hypothesis, initiation of signal transduction via immunoreceptors depends on interactions of the engaged immunoreceptor with…”
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AMT: Preclinical pharmacology studies by NIAZI, Faiz, DREVS, Joachim, DIERGARTEN, Klaus, DORN, Annette, MAIER, Armin, FIEBIG, Heinz Herbert, BRUYNS, Eddy, SCHEELE, Jürgen

“…Auron-Misheil-Therapy (AMT) consisting of aqueous camomile extract supplemented with calcium, vitamins, the antihistamine chlorpheniramine and human insulin is…”
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T cell receptor (TCR) interacting molecule (TRIM), a novel disulfide-linked dimer associated with the TCR-CD3-zeta complex, recruits intracellular signaling proteins to the plasma membrane by Bruyns, E, Marie-Cardine, A, Kirchgessner, H, Sagolla, K, Shevchenko, A, Mann, M, Autschbach, F, Bensussan, A, Meuer, S, Schraven, B

“…The molecular mechanisms regulating recruitment of intracellular signaling proteins like growth factor receptor-bound protein 2 (Grb2), phospholipase Cgamma1,…”
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Molecular Cloning of SKAP55, a Novel Protein That Associates with the Protein Tyrosine Kinase p59 in Human T-lymphocytes by Marie-Cardine, Anne, Bruyns, Eddy, Eckerskorn, Christoph, Kirchgessner, Henning, Meuer, Stefan C., Schraven, Burkhart

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The transmembrane adaptor protein TRIM regulates T cell receptor (TCR) expression and TCR-mediated signaling via an association with the TCR zeta chain by Kirchgessner, H, Dietrich, J, Scherer, J, Isomäki, P, Korinek, V, Hilgert, I, Bruyns, E, Leo, A, Cope, A P, Schraven, B

“…T cell receptor (TCR)-interacting molecule (TRIM) is a recently identified transmembrane adaptor protein, which is exclusively expressed in T cells. Here we…”
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SHP2-interacting transmembrane adaptor protein (SIT), a novel disulfide-linked dimer regulating human T cell activation by Marie-Cardine, A, Kirchgessner, H, Bruyns, E, Shevchenko, A, Mann, M, Autschbach, F, Ratnofsky, S, Meuer, S, Schraven, B

“…T lymphocytes express several low molecular weight transmembrane adaptor proteins that recruit src homology (SH)2 domain-containing intracellular molecules to…”
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Hematopoietic development of embryonic stem cells in vitro: cytokine and receptor gene expression by SCHMITT, R. M, BRUYNS, E, SNODGRASS, H. R

“…A novel system to study early hematopoietic development is described. This report documents the in vitro capacity of murine embryonic stem (ES) cells to…”
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Biochemical and functional analysis of mice deficient in expression of the CD45‐associated phosphoprotein LPAP by Ding, Isabelle, Bruyns, Eddy, Li, Ping, Magada, Diane, Paskind, Michael, Rodman, Laura, Seshadri, Tara, Alexander, Denis, Giese, Thomas, Schraven, Burkhart

“…The role of the CD45‐associated phosphoprotein (LPAP / CD45‐AP) during an immune response remains unclear. To understand better the function of LPAP we…”
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LPAP, a novel 32-kDa phosphoprotein that interacts with CD45 in human lymphocytes by Schraven, B, Schoenhaut, D, Bruyns, E, Koretzky, G, Eckerskorn, C, Wallich, R, Kirchgessner, H, Sakorafas, P, Labkovsky, B, Ratnofsky, S

“…CD45, a leukocyte-specific protein tyrosine phosphatase involved in signal transduction, has previously been shown to associate with a 32-kDa phosphoprotein in…”
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Biochemical analysis of the CD45-p56lck complex in Jurkat T cells lacking expression of lymphocyte phosphatase-associated phosphoprotein by Bruyns, Eddy, Kirchgessner, Henning, Meuer, Stefan, Burkhart Schraven

“…In human and mouse lymphocytes the protein tyrosine phosphatase CD45, a key molecule involved in T cell activation, non-covalently associates with the tyrosine…”
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Biochemical analysis of the CD45-p56(lck) complex in Jurkat T cells lacking expression of lymphocyte phosphatase-associated phosphoprotein by Bruyns, E, Kirchgessner, H, Meuer, S, Schraven, B

“…In human and mouse lymphocytes the protein tyrosine phosphatase CD45, a key molecule involved in T cell activation, non-covalently associates with the tyrosine…”
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Complete sequence, genomic organization, and chromosomal localization of the human gene encoding the SHP2-interacting transmembrane adaptor protein (SIT) by Hübener, C, Mincheva, A, Lichter, P, Schraven, B, Bruyns, E

“…In the present study, we isolated the SIT gene from a human P-1-derived atificial chromosome (PAC) library and determined the exon-intron junctions. We…”
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Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59 fyn in human T-lymphocytes by Marie-Cardine, Anne, Bruyns, Eddy, Verhagen, Anne M., Eckerskorn, Christoph, Kirchgessner, Henning, Meuer, Stefan C., Schraven, Burkhart

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Genomic organization and chromosomal localization of the human gene encoding the T-cell receptor-interacting molecule (TRIM) by Hübener, C, Mincheva, A, Lichter, P, Schraven, B, Bruyns, E

“…The primary signal for human T-cell activation is mediated through the interaction of the polymorphic T-cell receptor (TCR) with its natural ligand, antigenic…”
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Molecular cloning of SKAP55, a novel protein that associates with the protein tyrosine kinase p59 in human T-lymphocytes by Marie-Cardine, Anne, Bruyns, Eddy, Verhagen, Anne M., Eckerskorn, Christoph, Kirchgessner, Henning, Meuer, Stefan C., Schraven, Burkhart

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Restricted alpha/beta receptor gene usage of idiotype-specific major histocompatibility complex-restricted T cells: selection for CDR3-related sequences by Snodgrass, H R, Fisher, A M, Bruyns, E, Bogen, B

“…We have sequenced the T cell receptor (TcR) V alpha and V beta genes of seven independent BALB/c CD4+ T cell clones specific for the immunoglobulin lambda 2…”
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