Search Results - "Bruyere, Helene"

MYC fireworks by Bruyère, Hélène, Gillan, Tanya

Get full text

Causes of hypereosinophilia in 100 consecutive patients by Moller, Daniel, Tan, Julia, Gauiran, Deonne Thaddeus V., Medvedev, Nadia, Hudoba, Monika, Carruthers, Mollie N., Dehghan, Natasha, Berghe, Janette, Bruyère, Helene, Chen, Luke Y.C.

“…Background Hypereosinophilia (HE, persistent peripheral blood eosinophilia > 1.5 × 109/L) and hypereosinophilic syndrome (HES, HE with end‐organ damage) are…”
Get full text

Chronic lymphocytic leukemia patients with HLA-B27 referred for allogeneic hematopoietic stem cell transplantation do not have worse outcomes: Results of a population-based case series analysis in British Columbia, Canada by Huang, Steven J., Chan, Jonathan, Bruyère, Helene, Allan, Lenka L., Gerrie, Alina S., Toze, Cynthia L.

“…•outcomes were not different for HLA-B27 CLL patients with/without spondyloarthritis.•HLA-B27 does not influence clinical course of CLL patients for marrow…”
Get full text

Tuning the pH sensitivities of orthoester based compounds for drug delivery applications by simple chemical modification by Bruyère, Hélène, Westwell, Andrew D., Jones, Arwyn T.

“…Small chemical modifications influence aqueous pH-sensitivity of orthoester conjugates. Orthoesters are acid-sensitive moieties that allow substantial…”
Get full text

BPES with atypical premature ovarian insufficiency, and evidence of mitotic recombination, in a woman with trisomy X and a translocation t(3;11)(q22.3;q14.1) by Schlade‐Bartusiak, Kamilla, Brown, Lindsay, Lomax, Brenda, Bruyère, Hélène, Gillan, Tanya, Hamilton, Sara, McGillivray, Barbara, Eydoux, Patrice

“…Blepharophimosis–ptosis–epicanthus inversus syndrome (BPES) is a rare autosomal dominant disorder characterized by a complex dysgenesis of the eyelids and…”
Get full text

Imatinib mesylate responsiveness in aggressive systemic mastocytosis: Novel association with a platelet derived growth factor receptor beta mutation by Dalal, Bakul I., Horsman, Douglas E., Bruyèrè, Hélène, Forrest, Donna L

Get full text

Minimal Diagnostic Value of Karyotyping for Suspected Myelodysplastic Syndrome in the Absence of Bone Marrow Dysplasia by Trinder, Mark, Bruyere, Helene, McGinnis, Eric

Get full text

Two new Translocations Involving RUNX1 by Bruyere, Helene

Get full text

45 - Two new Translocations Involving RUNX1 by Bruyere, Helene

Get full text

Multicolor Karyotyping and Clinicopathological Analysis of Three Intravascular Lymphoma Cases by Khoury, Haytham, Lestou, Valia S, Gascoyne, Randy D, Bruyere, Helene, Li, Charles H, Nantel, Stephen H, Dalal, Bakul I, Naiman, Shelly C, Horsman, Douglas E

“…Intravascular lymphoma (IVL) is a rare neoplastic disease characterized by the presence of large malignant lymphoid cells in small vessels. It is often…”
Get full text

14. Concurrent systemic mastocytosis and T-lymphoblastic lymphoma unified by a novel cryptic JAKMIP2::PDGFRB rearrangement by Shopsowitz, Kevin, Hamadeh, Zeid, Stubbins, Ryan, Merkeley, Hayley, Bruyere, Helene, Bahmanyar, Mohammad, McGinnis, Eric

Get full text

Influence of cytogenetics in patients with relapsed or refractory multiple myeloma treated with lenalidomide plus dexamethasone: adverse effect of deletion 17p13 by Reece, Donna, Song, Kevin W., Fu, Tommy, Roland, Birgitte, Chang, Hong, Horsman, Douglas E., Mansoor, Adnan, Chen, Christine, Masih-Khan, Esther, Trieu, Young, Bruyere, Helene, Stewart, Douglas A., Bahlis, Nizar J.

“…Although the combination of lenalidomide and dexamethasone is effective therapy for patients with relapsed/refractory multiple myeloma, the influence of…”
Get full text

CLL-617 Long Term Outcomes and Secondary Malignancies in 673 Patients Treated With Oral Fludarabine and Intravenous Rituximab (FR) for Chronic Lymphocytic Leukemia (CLL) in British Columbia (BC), CanadaElys by VanderVeer, Elysha, Huang, Steven J.T., Bruyere, Helene, Li, Charles, Ramadan, Khaled, Villa, Diego, Scott, David W., Savage, Kerry J., Connors, Joseph M., Sehn, Laurie H., Toze, Cynthia L., Gerrie, Alina S.

“…Despite treatment shifting towards novel agents, chemoimmunotherapy remains a standard frontline CLL treatment in many countries. We report long-term survival…”
Get full text

POSTER: CLL-617 Long Term Outcomes and Secondary Malignancies in 673 Patients Treated With Oral Fludarabine and Intravenous Rituximab (FR) for Chronic Lymphocytic Leukemia (CLL) in British Columbia (BC), CanadaElys by VanderVeer, Elysha, Huang, Steven J.T., Bruyere, Helene, Li, Charles, Ramadan, Khaled, Villa, Diego, Scott, David W., Savage, Kerry J., Connors, Joseph M., Sehn, Laurie H., Toze, Cynthia L., Gerrie, Alina S.

Get full text

Oral Fludarabine and Intravenous Rituximab (FR) for Chronic Lymphocytic Leukemia (CLL): Long Term Outcomes and Secondary Malignancies in 673 Patients Treated in British Columbia (BC) by Vanderveer, Elysha, Huang, Steven J.T., Bruyere, Helene, Gillan, Tanya, Li, Charles H., Ramadan, Khaled, Villa, Diego, Scott, David W., Savage, Kerry J, Connors, Joseph M, Sehn, Laurie H, Toze, Cynthia L, Gerrie, Alina S

“…Background: Oral fludarabine and intravenous rituximab (FR) was the standard first-line therapy for CLL or small lymphocytic lymphoma (SLL) patients (pts) in…”
Get full text

Concomitant and successive amplifications of MYC in APL-like leukemia by Bruyère, Hélène, Sutherland, Heather, Chipperfield, Katherine, Hudoba, Monika

“…Abstract A 61-year-old male patient presented with very high blood white cell count, left shift of granulocytes to blasts, as well as low hemoglobin and…”
Get full text

Comparison of real-world treatment patterns in chronic lymphocytic leukemia management before and after availability of ibrutinib in the province of British Columbia, Canada by Huang, Steven J., Gerrie, Alina S., Young, Sean, Tucker, Tracy, Bruyere, Helene, Hrynchak, Monica, Galbraith, Paul, Al Tourah, Abdulwahab J., Dueck, Gregory, Noble, Michael C., Ramadan, Khaled M., Tsang, Peter, Hardy, Edward, Sehn, Laurie, Toze, Cynthia L.

“…•Ibrutinib has replaced chemoimmunotherapy as preferred therapy in CLL during relapse.•There has been an improvement in survival with introduction of…”
Get full text

Unsuccessful Cytogenetics and Outcomes in Acute Leukemia by Lee, Lauren, Bruyere, Helene, Barnett, Michael J, Broady, Raewyn, Forrest, Donna L., Gerrie, Alina S., Hogge, Donna E., Nantel, Stephen H., Narayanan, Sujaatha, Power, Maryse, Sanford, David, Song, Kevin, Sutherland, Heather J., Toze, Cynthia L, White, Jennifer, Abou Mourad, Yasser

“…Introduction: Cytogenetic features at diagnosis have significant independent prognostic impact in acute myeloid leukemia (AML) and acute lymphoblastic leukemia…”
Get full text

Ultrasensitive Detection of NOTCH1 c.7544_7545delCT Mutations in Chronic Lymphocytic Leukemia by Droplet Digital PCR Reveals High Frequency of Subclonal Mutations and Predicts Clinical Outcome in Cases with Trisomy 12 by Hoofd, Catherine, Huang, Steven J., Gusscott, Samuel, Lam, Sonya, Wong, Rachel, Johnston, Alexa, Ben-Neriah, Susana, Steidl, Christian, Scott, David W., Bruyere, Helene, Gillan, Tanya L., Toze, Cynthia L., Gerrie, Alina S., Weng, Andrew P.

“…NOTCH1 is recurrently mutated in chronic lymphocytic leukemia (CLL), most commonly as a 2-bp frameshift deletion (c.7541_7542delCT). This mutated allele…”
Get full text

Evidence-based review of genomic aberrations in B-lymphoblastic leukemia/lymphoma: Report from the cancer genomics consortium working group for lymphoblastic leukemia by Akkari, Yassmine M.N., Bruyere, Helene, Hagelstrom, R. Tanner, Kanagal-Shamanna, Rashmi, Liu, Jie, Luo, Minjie, Mikhail, Fady M., Pitel, Beth A., Raca, Gordana, Shago, Mary, Shao, Lina, Smith, Lisa R., Smolarek, Teresa A., Yenamandra, Ashwini, Baughn, Linda B.

“…•This evidence-based review presents a detailed description of genomic aberrations in all categories of B-lymphoblastic leukemia including clinical outcomes,…”
Get full text