Search Results - "Bruss, Matthew D."

Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates by Bruss, Matthew D, Khambatta, Cyrus F, Ruby, Maxwell A, Aggarwal, Ishita, Hellerstein, Marc K

“…Calorie restriction (CR) increases longevity and retards the development of many chronic diseases, but the underlying metabolic signals are poorly understood…”
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Integrative analysis of a cross-loci regulation network identifies App as a gene regulating insulin secretion from pancreatic islets by Tu, Zhidong, Keller, Mark P, Zhang, Chunsheng, Rabaglia, Mary E, Greenawalt, Danielle M, Yang, Xia, Wang, I-Ming, Dai, Hongyue, Bruss, Matthew D, Lum, Pek Y, Zhou, Yun-Ping, Kemp, Daniel M, Kendziorski, Christina, Yandell, Brian S, Attie, Alan D, Schadt, Eric E, Zhu, Jun

“…Complex diseases result from molecular changes induced by multiple genetic factors and the environment. To derive a systems view of how genetic loci interact…”
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Increased Phosphorylation of Akt Substrate of 160 kDa (AS160) in Rat Skeletal Muscle in Response to Insulin or Contractile Activity by BRUSS, Matthew D, ARIAS, Edward B, LIENHARD, Gustav E, CARTEE, Gregory D

“…Increased Phosphorylation of Akt Substrate of 160 kDa (AS160) in Rat Skeletal Muscle in Response to Insulin or Contractile Activity Matthew D. Bruss 1 , Edward…”
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Fibroblast growth factor 21 is not required for the reductions in circulating insulin-like growth factor-1 or global cell proliferation rates in response to moderate calorie restriction in adult mice by Thompson, Airlia C S, Bruss, Matthew D, Nag, Nitish, Kharitonenkov, Alexei, Adams, Andrew C, Hellerstein, Marc K

“…Calorie restriction (CR) delays aging and extends lifespan in numerous organisms, including mice. Down-regulation of the somatotropic axis, including a…”
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The effects of physiological adaptations to calorie restriction on global cell proliferation rates by Bruss, Matthew D, Thompson, Airlia C S, Aggarwal, Ishita, Khambatta, Cyrus F, Hellerstein, Marc K

“…Calorie restriction (CR) reduces the rate of cell proliferation in mitotic tissues. It has been suggested that this reduction in cell proliferation may mediate…”
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A comprehensive assessment of mitochondrial protein synthesis and cellular proliferation with age and caloric restriction by Miller, Benjamin F., Robinson, Matthew M, Bruss, Matthew D., Hellerstein, Marc, Hamilton, Karyn L.

“…Summary It is proposed that caloric restriction (CR) increases mitochondrial biogenesis. However, it is not clear why CR increases an energetically costly…”
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Differential translational control of 5′ IRE-containing mRNA in response to dietary iron deficiency and acute iron overload by Garza, Kerry R, Clarke, Stephen L, Ho, Yi-Hsuan, Bruss, Matthew D, Vasanthakumar, Aparna, Anderson, Sheila A, Eisenstein, Richard S

“…Iron regulatory proteins (IRPs) are iron-responsive RNA binding proteins that dictate changes in cellular iron metabolism in animal cells by controlling the…”
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The Effect of Long Term Calorie Restriction on in Vivo Hepatic Proteostatis: A Novel Combination of Dynamic and Quantitative Proteomics by Price, John C., Khambatta, Cyrus F., Li, Kelvin W., Bruss, Matthew D., Shankaran, Mahalakshmi, Dalidd, Marcy, Floreani, Nicholas A., Roberts, Lindsay S., Turner, Scott M., Holmes, William E., Hellerstein, Marc K.

“…Calorie restriction (CR) promotes longevity. A prevalent mechanistic hypothesis explaining this effect suggests that protein degradation, including…”
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Signaling from β1- and β2-adrenergic receptors is defined by differential interactions with PDE4 by Richter, Wito, Day, Peter, Agrawal, Rani, Bruss, Matthew D, Granier, Sébastien, Wang, Yvonne L, Rasmussen, Søren G F, Horner, Kathleen, Wang, Ping, Lei, Tao, Patterson, Andrew J, Kobilka, Brian, Conti, Marco

“…β 1 ‐ and β 2 ‐adrenergic receptors (βARs) are highly homologous, yet they play clearly distinct roles in cardiac physiology and pathology. Myocyte…”
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Reduced in vivo hepatic proteome replacement rates but not cell proliferation rates predict maximum lifespan extension in mice by Thompson, Airlia C. S., Bruss, Matthew D., Price, John C., Khambatta, Cyrus F., Holmes, William E., Colangelo, Marc, Dalidd, Marcy, Roberts, Lindsay S., Astle, Clinton M., Harrison, David E., Hellerstein, Marc K.

“…Summary Combating the social and economic consequences of a growing elderly population will require the identification of interventions that slow the…”
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Calorie restriction does not increase short-term or long-term protein synthesis by Miller, Benjamin F, Robinson, Matthew M, Reuland, Danielle J, Drake, Joshua C, Peelor, 3rd, Frederick F, Bruss, Matthew D, Hellerstein, Marc K, Hamilton, Karyn L

“…Increased protein synthesis is proposed as a mechanism of life-span extension during caloric restriction (CR). We hypothesized that CR does not increase…”
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Critical Role of PDE4D in β2-Adrenoceptor-dependent cAMP Signaling in Mouse Embryonic Fibroblasts by Bruss, Matthew D., Richter, Wito, Horner, Kathleen, Jin, S.-L. Catherine, Conti, Marco

“…One of the defining properties of β2-adrenergic receptor (β2AR) signaling is the transient and rapidly reversed accumulation of cAMP. Here we have investigated…”
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Inhibition of mitogen-activated protein kinase kinase blocks proliferation of neural progenitor cells by Learish, Randall D, Bruss, Matthew D, Haak-Frendscho, Mary

“…Nestin-expressing neural progenitor (NP) cells have been isolated from the subventricular zone (SVZ) of the brain and propagated with epidermal growth factor…”
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A Method Utilizing Ultra-High Performance Liquid Chromatography with Ultraviolet and Mass Spectrometric Detection for the Analysis of Material Extracts Produced during a Controlled Extraction Study by Zdravkovic, Steven A, Bruss, Matthew D, Piccoli, Robert F, Wood, Derek M

“…Pharmaceutical packaging/delivery systems and medical devices are characterized via a controlled extraction study as part of the development process for new…”
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The effect of calorie restriction and exercise on cell proliferation rates in female mice by Thompson, Airlia, Bruss, Matthew D

“…Calorie restriction (CR) inhibits tumor growth, which is associated with reduced cell proliferation in tumorigenic tissues. Exercise also slows tumor growth,…”
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Critical role of PDE4D in beta2-adrenoceptor-dependent cAMP signaling in mouse embryonic fibroblasts by Bruss, Matthew D, Richter, Wito, Horner, Kathleen, Jin, S-L Catherine, Conti, Marco

“…One of the defining properties of beta2-adrenergic receptor (beta(2)AR) signaling is the transient and rapidly reversed accumulation of cAMP. Here we have…”
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Critical Role of PDE4D in β2-Adrenoceptor-dependent cAMP Signaling in Mouse Embryonic FibroblastsS by Bruss, Matthew D., Richter, Wito, Horner, Kathleen, Jin, S.-L. Catherine, Conti, Marco

“…One of the defining properties of β 2 -adrenergic receptor (β 2 AR) signaling is the transient and rapidly reversed accumulation of cAMP. Here we have…”
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Critical Role of PDE4D in β2-Adrenoceptor-dependent cAMP Signaling in Mouse Embryonic Fibroblasts by Matthew D. Bruss, Wito Richter, Kathleen Horner, S.-L. Catherine Jin, Marco Conti

“…One of the defining properties of β 2 -adrenergic receptor (β 2 AR) signaling is the transient and rapidly reversed accumulation of cAMP. Here we have…”
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Signaling from β1‐ and β2‐adrenergic receptors is defined by differential interactions with PDE4 by Richter, Wito, Day, Peter, Agrawal, Rani, Bruss, Matthew D., Granier, Sébastien, Wang, Yvonne L., Rasmussen, Søren G.F., Horner, Kathleen, Wang, Ping, Lei, Tao, Patterson, Andrew J., Kobilka, Brian, Conti, Marco

“…Abstract only β1‐ and β2‐adrenergic receptors (βARs) are highly homologous, yet they play clearly distinct roles in cardiac physiology and pathology. Myocyte…”
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Signaling from β 1 - and β 2 -adrenergic receptors is defined by differential interactions with PDE4 by Conti, Marco, Richter, Wito, Day, Peter, Agrawal, Rani, Bruss, Matthew D, Granier, Sébastien, Wang, Yvonne L, Rasmussen, Søren G F, Horner, Kathleen, Wang, Ping, Lei, Tao, Patterson, Andrew J, Kobilka, Brian

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