Search Results - "Bruse, Petra"

Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease by Linsel-Nitschke, Patrick, Heeren, Jörg, Aherrahrou, Zouhair, Bruse, Petra, Gieger, Christian, Illig, Thomas, Prokisch, Holger, Heim, Katharina, Doering, Angela, Peters, Annette, Meitinger, Thomas, Wichmann, H.-Erich, Hinney, Anke, Reinehr, Thomas, Roth, Christian, Ortlepp, Jan. R, Soufi, Mouhidien, Sattler, Alexander M, Schaefer, Jürgen, Stark, Klaus, Hengstenberg, Christian, Schaefer, Arne, Schreiber, Stefan, Kronenberg, Florian, Samani, Nilesh J, Schunkert, Heribert, Erdmann, Jeanette

“…Abstract Background A single nucleotide polymorphism (SNP) rs599839 located at chromosome 1p13.3 has previously been associated with risk of coronary artery…”
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Effect of Differences in the Microbiome of Cyp17a1 -Deficient Mice on Atherosclerotic Background by Künstner, Axel, Aherrahrou, Redouane, Hirose, Misa, Bruse, Petra, Ibrahim, Saleh Mohamed, Busch, Hauke, Erdmann, Jeanette, Aherrahrou, Zouhair

“…CYP17A1 is a cytochrome P450 enzyme that has 17-alpha-hydroxylase and C17,20-lyase activities. deficiency is associated with high body mass and visceral fat…”
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The 4977bp deletion of mitochondrial DNA in human skeletal muscle, heart and different areas of the brain: A useful biomarker or more? by Meissner, Christoph, Bruse, Petra, Mohamed, Salaheldien Ali, Schulz, Anja, Warnk, Hanne, Storm, Thilo, Oehmichen, Manfred

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Dysfunctional nitric oxide signalling increases risk of myocardial infarction by Erdmann, Jeanette, Stark, Klaus, Esslinger, Ulrike B., Rumpf, Philipp Moritz, Koesling, Doris, de Wit, Cor, Kaiser, Frank J., Braunholz, Diana, Medack, Anja, Fischer, Marcus, Zimmermann, Martina E., Tennstedt, Stephanie, Graf, Elisabeth, Eck, Sebastian, Aherrahrou, Zouhair, Nahrstaedt, Janja, Willenborg, Christina, Bruse, Petra, Brænne, Ingrid, Nöthen, Markus M., Hofmann, Per, Braund, Peter S., Mergia, Evanthia, Reinhard, Wibke, Burgdorf, Christof, Schreiber, Stefan, Balmforth, Anthony J., Hall, Alistair S., Bertram, Lars, Steinhagen-Thiessen, Elisabeth, Li, Shu-Chen, März, Winfried, Reilly, Muredach, Kathiresan, Sekar, McPherson, Ruth, Walter, Ulrich, Ott, Jurg, Samani, Nilesh J., Strom, Tim M., Meitinger, Thomas, Hengstenberg, Christian, Schunkert, Heribert

“…Two private, heterozygous mutations in two functionally related genes, GUCY1A3 and CCT7 , are identified in an extended family with myocardial infarction;…”
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New susceptibility locus for coronary artery disease on chromosome 3q22.3 by Perret, Claire, Blankenberg, Stefan, Stark, Klaus, Braund, Peter S, Rubin, Diana, Deloukas, Panos, Ball, Stephen G, Schäfer, Arne, Thompson, John R, Voight, Benjamin F, Zeller, Tanja, Schunkert, Heribert, Ouwehand, Willem H, Merlini, Piera Angelica, Schrezenmeir, Jürgen, Linsel-Nitschke, Patrick, Bernardinelli, Luisa, Elosua, Roberto, Wright, Ben, Peyvandi, Flora, Schillert, Arne, Meisinger, Christa, Hengstenberg, Christian, Samani, Nilesh J, Salomaa, Veikko, Peltonen, Leena, Melander, Olle, Schreiber, Stefan, Trégouët, David-Alexandre, Mokhtari, Nour Eddine El, Schwarz, Daniel F, Balmforth, Anthony J, Kathiresan, Sekar, Wagner, Arnika K, Siscovick, David S, Schwartz, Stephen M, Bugert, Peter, Ardissino, Diego, König, Inke R, Aherrahrou, Zouhair, Wild, Philipp, Erdmann, Jeanette, Baumert, Jens, Renner, Wilfried, Bruse, Petra, Klüter, Harald, Altshuler, David, März, Winfried, Wichmann, H-Erich, Ziegler, Andreas, Fischer, Marcus, Hall, Alistair S, Cambien, Francois, Meitinger, Thomas, Großhennig, Anika, Tiret, Laurence, O'Donnell, Christopher J, Peters, Annette

“…We present a three-stage analysis of genome-wide SNP data in 1,222 German individuals with myocardial infarction and 1,298 controls, in silico replication in…”
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Serum microRNA-1233 is a specific biomarker for diagnosing acute pulmonary embolism by Kessler, Thorsten, Erdmann, Jeanette, Vilne, Baiba, Bruse, Petra, Kurowski, Volkhard, Diemert, Patrick, Schunkert, Heribert, Sager, Hendrik B

“…Circulating microRNAs (miRNAs) emerge as novel biomarkers in cardiovascular diseases. Diagnosing acute pulmonary embolism (PE) remains challenging due to a…”
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The 4977 bp deletion of mitochondrial DNA in human skeletal muscle, heart and different areas of the brain: A useful biomarker or more? by Meissner, Christoph, Bruse, Petra, Mohamed, Salaheldien Ali, Schulz, Anja, Warnk, Hanne, Storm, Thilo, Oehmichen, Manfred

“…It has been suggested that deletions of mitochondrial DNA (mtDNA) are important players with regard to the ageing process. Since the early 1990s, the 4977 bp…”
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Genome-wide association study identifies a new locus for coronary artery disease on chromosome 10p11.23 by ERDMANN, Jeanette, WILLENBORG, Christina, AHERRAHROU, Zouhair, KLOPP, Norman, LOLEY, Christina, STARK, Klaus, HENGSTENBERG, Christian, BRUSE, Petra, FREYER, Jennifer, WAGNER, Arnika K, MEDACK, Anja, LIEB, Wolfgang, NAHRSTAEDT, Janja, GROSSHENNIG, Anika, SAGER, Hendrik B, REINHARDT, Adrian, SCHÄFER, Arne, SCHREIBER, Stefan, EDDINE EL MOKHTARI, Nour, RAAZ-SCHRAUDER, Dorette, ILLIG, Thomas, GARLICHS, Christoph D, EKICI, Arif B, PREUSS, Michael, REIS, André, SCHREZENMEIR, Jürgen, RUBIN, Diana, ZIEGLER, Andreas, WICHMANN, H.-E, DOERING, Angela, MEISINGER, Christa, MEITINGER, Thomas, PETERS, Annette, SCHUNKERT, Heribert, KÖNIG, Inke R, BAUMERT, Jens, LINSEL-NITSCHKE, Patrick, GIEGER, Christian, TENNSTEDT, Stephanie, BELCREDI, Petra

“…Recent genome-wide association (GWA) studies identified 10 chromosomal loci for coronary artery disease (CAD) or myocardial infarction (MI). However, these…”
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Large Scale Association Analysis of Novel Genetic Loci for Coronary Artery Disease by Samani, N J, Deloukas, P, Erdmann, J, Hengstenberg, C, Kuulasmaa, K, McGinnis, R, Schunkert, H, Soranzo, N, Thompson, J, Tiret, L, Ziegler, A

“…Combined analysis of 2 genome-wide association studies in cases enriched for family history recently identified 7 loci (on 1p13.3, 1q41, 2q36.3, 6q25.1, 9p21,…”
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RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies by Herder, Christian, Peeters, Wouter, Illig, Thomas, Baumert, Jens, de Kleijn, Dominique P V, Moll, Frans L, Poschen, Ulrike, Klopp, Norman, Müller-Nurasyid, Martina, Roden, Michael, Preuss, Michael, Karakas, Mahir, Meisinger, Christa, Thorand, Barbara, Pasterkamp, Gerard, Koenig, Wolfgang, Assimes, Themistocles L, Deloukas, Panos, Erdmann, Jeanette, Holm, Hilma, Kathiresan, Sekar, König, Inke R, McPherson, Ruth, Reilly, Muredach P, Roberts, Robert, Samani, Nilesh J, Schunkert, Heribert, Stewart, Alexandre F R

“…The chemokine RANTES (regulated on activation, normal T-cell expressed and secreted)/CCL5 is involved in the pathogenesis of cardiovascular disease in mice,…”
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Lack of age-related increase of mitochondrial DNA amount in brain, skeletal muscle and human heart by Frahm, Thomas, Mohamed, Salaheldien A., Bruse, Petra, Gemünd, Christine, Oehmichen, Manfred, Meissner, Christoph

“…During the ageing process, an increase of mitochondrial DNA (mtDNA) deletions and other mutations have been reported. These structural alterations of mtDNA are…”
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Tissue-specific deletion patterns of the mitochondrial genome with advancing age by Meissner, Christoph, Bruse, Petra, Oehmichen, Manfred

“…Aging is a multifactorial process and a lot of theories have been put forward to explain the deterioration of organ function with advancing age. The free…”
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Genetic variation in the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) is associated with myocardial infarction in the German population by Linsel-Nitschke, Patrick, Götz, Anika, Medack, Anja, König, Inke R, Bruse, Petra, Lieb, Wolfgang, Mayer, Björn, Stark, Klaus, Hengstenberg, Christian, Fischer, Marcus, Baessler, Andrea, Ziegler, Andreas, Schunkert, Heribert, Erdmann, Jeanette

“…Genetic variation in the genes ALOX5AP (arachidonate 5-lipoxygenase-activating protein) and LTA4H (leukotriene A4 hydrolase) has previously been shown to…”
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Abstract 3452: The Common Variant Rs9939609 In The FTO Gene Is Associated With Myocardial Infarction In Two Large German Populations (German Family MI Study And KORA-B) by Erdmann, Jeanette, Götz, Anika, Bruse, Petra, Medack, Anja, Lieb, Wolfgang, Fischer, Marcus, Baessler, Andrea, Stark, Klaus, Hengstenberg, Christian, Ziegler, Andreas, Schunkert, Heribert

“…Abstract only Very recently, a genome-wide search for type 2 diabetes susceptibility genes identified a common variant in the FTO gene that predisposes to…”
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Lack of association of genetic variants in the LRP8 gene with familial and sporadic myocardial infarction by Lieb, Wolfgang, Zeller, Tanja, Mangino, Massimo, Götz, Anika, Braund, Peter, Wenzel, Juergen J., Horn, Christian, Proust, Carole, Linsel-Nitschke, Patrick, Amouyel, Philippe, Bruse, Petra, Arveiler, Dominique, König, Inke R., Ferrières, Jean, Ziegler, Andreas, Balmforth, Anthony J., Evans, Alun, Ducimetière, Pierre, Cambien, Francois, Hengstenberg, Christian, Stark, Klaus, Hall, Alistair S., Schunkert, Heribert, Blankenberg, Stefan, Samani, Nilesh J., Erdmann, Jeanette, Tiret, Laurence

“…Coronary artery disease (CAD) and myocardial infarction (MI) have a genetic basis, but the precise genetic underpinning remains controversial. Recently, an…”
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The sialate‐pyruvate lyase from pig kidney by Traving, Christina, Bruse, Petra, Wächter, Andrea, Schauer, Roland

“…The first complete primary structure of a mammalian sialate‐pyruvate lyase, namely of the enzyme from porcine kidney, was elucidated by a combination of…”
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The sialate-pyruvate lyase from pig kidney. Elucidation of the primary structure and expression of recombinant enzyme activity by Traving, C, Bruse, P, Wächter, A, Schauer, R

“…The first complete primary structure of a mammalian sialate-pyruvate lyase, namely of the enzyme from porcine kidney, was elucidated by a combination of…”
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