Search Results - "Brusco, Concetta"

Plexin-B2 facilitates glioblastoma infiltration by modulating cell biomechanics by Huang, Yong, Tejero, Rut, Lee, Vivian K., Brusco, Concetta, Hannah, Theodore, Bertucci, Taylor B., Junqueira Alves, Chrystian, Katsyv, Igor, Kluge, Michael, Foty, Ramsey, Zhang, Bin, Friedel, Caroline C., Dai, Guohao, Zou, Hongyan, Friedel, Roland H.

“…Infiltrative growth is a major cause of high lethality of malignant brain tumors such as glioblastoma (GBM). We show here that GBM cells upregulate guidance…”
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Hypoxic niches attract and sequester tumor-associated macrophages and cytotoxic T cells and reprogram them for immunosuppression by Sattiraju, Anirudh, Kang, Sangjo, Giotti, Bruno, Chen, Zhihong, Marallano, Valerie J., Brusco, Concetta, Ramakrishnan, Aarthi, Shen, Li, Tsankov, Alexander M., Hambardzumyan, Dolores, Friedel, Roland H., Zou, Hongyan

“…Glioblastoma (GBM), a highly lethal brain cancer, is notorious for immunosuppression, but the mechanisms remain unclear. Here, we documented a temporospatial…”
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EXTH-04. ELUCIDATING THE PLEIOTROPIC EFFECTS OF VERTEPORFIN PHOTODYNAMIC THERAPY IN PRECLINICAL GLIOBLASTOMA MODELS by Price, Gabrielle, Sudhir, Sweta, Brusco, Concetta, Bouras, Alexandros, Tsankova, Nadejda, Hadjipanayis, Constantinos

“…Abstract Glioblastoma (GBM) has the highest mortality rate, incidence, and therapy resistance of all primary brain tumors. Deregulation of the epidermal growth…”
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TAMI-59. RECIPROCAL IMPACT OF CANCER IMMUNITY AND TUMOR HYPOXIA DURING GLIOBLASTOMA PROGRESSION by Sattiraju, Anirudh, Kang, Sangjo, Marallano, Valerie, Brusco, Concetta, Chen, Zhihong, Ramakrishnan, Aarthi, Shen, Li, Hambardzumyan, Dolores, Friedel, Roland, Zou, Hongyan

“…Abstract Tumor hypoxia is linked to poor outcome for glioblastoma (GBM), a highly malignant brain cancer, but the underlying mechanisms and the environmental…”
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TAMI-60. MODULATION OF CELL BIOMECHANICS THROUGH GUIDANCE RECEPTOR PLEXIN-B2 FACILITATES GLIOBLASTOMA INFILTRATION by Friedel, Roland, Huang, Yong, Tejero, Rut, Alves, Chrystian Junqueira, Brusco, Concetta, Hannah, Theodore, Lee, Vivian, Dai, Guohao, Zou, Hongyan

“…Abstract Infiltrative growth is a major cause of the high lethality of malignant brain tumors such as glioblastoma (GBM). The study of the contribution of…”
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TAMI-18. SINGLE-CELL SEQUENCING AND GENETIC LABELING TO CHARACTERIZE HYPOXIC GBM CELLS IN THEIR MICROENVIRONMENT by Sattiraju, Anirudh, Marallano, Valerie, Ramakrishnan, Aarthi, Brusco, Concetta, Shen, Li, Wojcinski, Alexandre, Kesari, Santosh, Friedel, Roland H, Zou, Hongyan

“…Abstract Glioblastoma (GBM) recurrence, arising from treatment-resistant hypoxic cells, is a major contributor to patient mortality. We have engineered GBM…”
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Investigations into Glioblastoma Hypoxia, the Tumor Microenvironment, and Diffuse Invasion by Brusco, Concetta T

“…Glioblastoma (GBM) is an incurable brain tumor as it inevitably recurs after standard treatments. Hypoxic cells are known to be resistant to treatments and…”
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