Search Results - "Brunt, ER"

Spinocerebellar ataxias in the Netherlands: Prevalence and age at onset variance analysis by VAN DE WARRENBURG, B. P. C, SINKE, R. J, KNOERS, N. V. A. M, KREMER, H. P. H, VERSCHUUREN-BEMELMANS, C. C, SCHEFFER, H, BRUNT, E. R, IPPEL, P. F, MAAT-KIEVIT, J. A, DOOIJES, D, NOTERMANS, N. C, LINDHOUT, D

“…International prevalence estimates of autosomal dominant cerebellar ataxias (ADCA) vary from 0.3 to 2.0 per 100,000. The prevalence of ADCA in the Netherlands…”
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Caspase‐mediated proteolysis of the polyglutamine disease protein ataxin‐3 by Berke, Sarah J Shoesmith, Schmied, Francisca A Flores, Brunt, Ewout R., Ellerby, Lisa M., Paulson, Henry L.

“…Spinocerebellar ataxia type‐3, also known as Machado‐Joseph Disease, is one of many inherited neurodegenerative disorders caused by polyglutamine‐encoding CAG…”
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Accumulation of aberrant ubiquitin induces aggregate formation and cell death in polyglutamine diseases by de Pril, Remko, Fischer, David F., Maat-Schieman, Marion L.C., Hobo, Barbara, de Vos, Rob A.I., Brunt, Ewout R., Hol, Elly M., Roos, Raymund A.C., van Leeuwen, Fred W.

“…Polyglutamine diseases are characterized by neuronal intranuclear inclusions (NIIs) of expanded polyglutamine proteins, indicating the failure of protein…”
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A 3-year randomized trial of ropinirole and bromocriptine in early Parkinson's disease by KORCZYN, A. D, BRUNT, E. R, LARSEN, J. P, NAGY, Z, POEWE, W. H, RUGGIERI, S

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Thalamic involvement in a spinocerebellar ataxia type 2 (SCA2) and a spinocerebellar ataxia type 3 (SCA3) patient, and its clinical relevance by Rüb, U., Del Turco, D., Del Tredici, K., de Vos, R. A. I., Brunt, E. R., Reifenberger, G., Seifried, C., Schultz, C., Auburger, G., Braak, H.

“…In spite of the considerable progress in clinical and molecular research, knowledge regarding brain damage in spinocerebellar ataxia type 2 (SCA2) and type 3…”
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Damage to the reticulotegmental nucleus of the pons in spinocerebellar ataxia type 1, 2, and 3 by Rüb, U, Bürk, K, Schöls, L, Brunt, E R, de Vos, R A I, Diaz, G Orozco, Gierga, K, Ghebremedhin, E, Schultz, C, Del Turco, D, Mittelbronn, M, Auburger, G, Deller, T, Braak, H

“…The reticulotegmental nucleus of the pons (RTTG) is among the precerebellar nuclei of the human brainstem. Although it represents an important component of the…”
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Ropinirole in the treatment of early Parkinson's disease: A 6-month interim report of a 5-year levodopa-controlled study by Rascol, Olivier, Brooks, David J., Brunt, Ehrout R., Korczyn, Amos D., Poewe, Warner H., Stocchi, Fabrizzio

“…The efficacies of ropinirole and levodopa were compared after 6 months of treatment in a planned interim analysis of a 5‐year, double‐blind, randomized,…”
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Spinocerebellar ataxias types 2 and 3: degeneration of the precerebellar nuclei isolates the three phylogenetically defined regions of the cerebellum by Rüb, U., Gierga, K., Brunt, E. R., de Vos, R. A. I., Bauer, M., Schöls, L., Bürk, K., Auburger, G., Bohl, J., Schultz, C., Vuksic, M., Burbach, G. J., Braak, H., Deller, T.

“…The precerebellar nuclei act as a gate for the entire neocortical, brainstem and spinal cord afferent input destined for the cerebellum. Since no…”
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Spinocerebellar ataxia type 3 (Machado–Joseph disease): severe destruction of the lateral reticular nucleus by Rüb, U., de Vos, R. A. I., Schultz, C., Brunt, E. R., Paulson, H., Braak, H.

“…The lateral reticular nucleus (LRT) of the medulla oblongata is a precerebellar nucleus involved in proprioception and somatomotor automatisms. We investigated…”
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Spinocerebellar Ataxia Type 7 (SCA7): First Report of a Systematic Neuropathological Study of the Brain of a Patient with a Very Short Expanded CAG-Repeat by Rüb, U, Brunt, ER, Gierga, K, Seidel, K, Schultz, C, Schöls, L, Auburger, G, Heinsen, H, Ippel, PF, Glimmerveen, WF, Wittebol-Post, D, Arai, K, Deller, T, de Vos, RAI

“…Spinocerebellar ataxia type 7 (ScA7) represents a very rare and severe autosomal dominantly inherited cerebellar ataxia (AdCA). It belongs to the group of…”
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Ropinirole versus bromocriptine in the treatment of early Parkinson's disease: A 6-month interim report of a 3-year study by Korczyn, Amos D., Brooks, David J., Brunt, Ehrout R., Poewe, Warner H., Rascol, Olivier, Stocchi, Fabrizzio

“…We compared the efficacy and safety of ropinirole with that of bromocriptine after 6 months of treatment in a planned interim analysis of a 3‐year,…”
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Degeneration of the central vestibular system in spinocerebellar ataxia type 3 (SCA3) patients and its possible clinical significance by Rüb, U., Brunt, E. R., De Vos, R. A. I., Del Turco, D., Del Tredici, K., Gierga, K., Schultz, C., Ghebremedhin, E., Bürk, K., Auburger, G., Braak, H.

“…Although the vestibular complex represents an important component of the neural circuits crucial for the maintenance of truncal and postural stability, and it…”
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A six-month multicentre, double-blind, bromocriptine-controlled study of the safety and efficacy of ropinirole in the treatment of patients with Parkinson's disease not optimally controlled by L-dopa by Brunt, Ehrout R, Brooks, David J, Korczyn, Amos D, Montasturc, Jean-Louis, Stocchi, Fabrizzio

“…To compare the safety and efficacy of ropinirole and bromocriptine as adjunct therapy in patients with Parkinson's disease (PD) not optimally controlled by…”
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Neurophysiological evaluation in children with Friedreich's ataxia by Sival, D.A, du Marchie Sarvaas, G.J, Brouwer, O.F, Uges, D.R, Verschuuren-Bemelmans, C.C, Maurits, N.M, Brunt, E.R, van der Hoeven, J.H

“…Abstract Introduction In children with Friedreich's ataxia (FRDA children), clinical ataxia outcomes are hardly substantiated by underlying neurophysiological…”
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Degeneration of the external cuneate nucleus in spinocerebellar ataxia type 3 (Machado–Joseph disease) by Rüb, U, de Vos, R.A.I, Brunt, E.R, Schultz, C, Paulson, H, Del Tredici, K, Braak, H

“…Owing to its anatomical connections, the external cuneate nucleus (ECU) plays a crucial role in processing proprioceptive input from the upper trunk and upper…”
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The nucleus raphe interpositus in spinocerebellar ataxia type 3 (Machado–Joseph disease) by Rüb, U., Brunt, E.R., Gierga, K., Schultz, C., Paulson, H., de Vos, R.A.I., Braak, H.

“…The nucleus raphe interpositus (RIP) plays an important role in the premotor network for saccades. Its omnipause neurons gate the activity of the burst neurons…”
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Guidelines for the pathoanatomical examination of the lower brain stem in ingestive and swallowing disorders and its application to a dysphagic spinocerebellar ataxia type 3 patient by Rüb, U., Brunt, E. R., Del Turco, D., De Vos, R. A. I., Gierga, K., Paulson, H., Braak, H.

“…U. Rüb, E. R. Brunt, D. Del Turco, R. A. I. de Vos, K. Gierga, H. Paulson and H. Braak (2003) Neuropathology and Applied Neurobiology 29, 1–13 
Guildelines for…”
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Episodic ataxia type 2: Three novel truncating mutations and one novel missense mutation in the CACNA1A gene by VAN DEN MAAGDENBERG, A. M. J. M, KORS, E. E, HAAN, J, FRANTS, R. R, FERRARI, M. D, BRUNT, E. R, VAN PAESSCHEN, W, PASCUAL, J, RAVINE, D, KEELING, S, VANMOLKOT, K. R. J, VERMEULEN, F. L. M. G, TERWINDT, G. M

“…We analysed the CACNA1A gene, located on chromosome 19p13, in three unrelated families and one sporadic case with episodic ataxia type 2 (EA-2). In two of the…”
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