Search Results - "Bruns, Karsten"

Phosphorylation of the influenza A virus protein PB1-F2 by PKC is crucial for apoptosis promoting functions in monocytes by Mitzner, David, Dudek, Sabine Eva, Studtrucker, Nicole, Anhlan, Darisuren, Mazur, Igor, Wissing, Josef, Jänsch, Lothar, Wixler, Ludmilla, Bruns, Karsten, Sharma, Alok, Wray, Victor, Henklein, Peter, Ludwig, Stephan, Schubert, Ulrich

“…The 11th influenza A virus (IAV) protein PB1-F2 is encoded by an alternative reading frame of the PB1 polymerase gene and found in the nucleus, cytosol and at…”
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Structural Characterization and Oligomerization of PB1-F2, a Proapoptotic Influenza A Virus Protein by Bruns, Karsten, Studtrucker, Nicole, Sharma, Alok, Fossen, Torgils, Mitzner, David, Eissmann, André, Tessmer, Uwe, Röder, René, Henklein, Peter, Wray, Victor, Schubert, Ulrich

“…Recently, a novel 87-amino acid influenza A virus protein with proapoptotic properties, PB1-F2, has been reported that originates from an alternative reading…”
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Solution Structure of the Human Immunodeficiency Virus Type 1 p6 Protein by Fossen, Torgils, Wray, Victor, Bruns, Karsten, Rachmat, Judhi, Henklein, Peter, Tessmer, Uwe, Maczurek, Annette, Klinger, Patricia, Schubert, Ulrich

“…The human immunodeficiency virus type 1 p6 protein represents a docking site for several cellular and viral binding factors and fulfills major roles in the…”
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Cyclophilin A Interacts with HIV-1 Vpr and Is Required for Its Functional Expression by Zander, Kerstin, Sherman, Michael P., Tessmer, Uwe, Bruns, Karsten, Wray, Victor, Prechtel, Alexander T., Schubert, Evelyn, Henklein, Peter, Luban, Jeremy, Neidleman, Jason, Greene, Warner C., Schubert, Ulrich

“…Viral protein R (Vpr) of human immunodeficiency virus, type 1 (HIV-1) is the major virion-associated accessory protein that affects a number of biological…”
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Functional and Structural Characterization of Synthetic HIV-1 Vpr That Transduces Cells, Localizes to the Nucleus, and Induces G2 Cell Cycle Arrest by Henklein, Peter, Bruns, Karsten, Sherman, Michael P., Tessmer, Uwe, Licha, Kai, Kopp, Jeffrey, de Noronha, Carlos M.C., Greene, Warner C., Wray, Victor, Schubert, Ulrich

“…Human immunodeficiency virus (HIV) Vpr contributes to nuclear import of the viral pre-integration complex and induces G2 cell cycle arrest. We describe the…”
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Proline 35 of Human Immunodeficiency Virus Type 1 (HIV-1) Vpr Regulates the Integrity of the N-Terminal Helix and the Incorporation of Vpr into Virus Particles and Supports the Replication of R5-Tropic HIV-1 in Human Lymphoid Tissue Ex Vivo by VOTTELER, Jörg, STUDTRUCKER, Nicole, SHARMA, Alok, WRAY, Victor, SCHUBERT, Ulrich, SÖRGEL, Stefan, MÜNCH, Jan, RÜCKER, Elke, KIRCHHOFF, Frank, SCHICK, Bernhard, HENKLEIN, Peter, FOSSEN, Torgils, BRUNS, Karsten

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Solution structure of the equine infectious anemia virus p9 protein: a rationalization of its different ALIX binding requirements compared to the analogous HIV-p6 protein by Sharma, Alok, Bruns, Karsten, Roder, Rene, Henklein, Peter, Votteler, Jorg, Wray, Victor, Schubert, Ulrich

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Structural Characterization of the HIV-1 Vpr N Terminus by Bruns, Karsten, Fossen, Torgils, Wray, Victor, Henklein, Peter, Tessmer, Uwe, Schubert, Ulrich

“…The 96-residue human immunodeficiency virus (HIV) accessory protein Vpr serves manifold functions in the retroviral life cycle including augmentation of viral…”
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Requirement of Specific Intrahelical Interactions for Stabilizing the Inactive Conformation of Glycoprotein Hormone Receptors by Schulz, Angela, Bruns, Karsten, Henklein, Peter, Krause, Gerd, Schubert, Mario, Gudermann, Thomas, Wray, Victor, Schultz, Günter, Schöneberg, Torsten

“…Systematic analysis of structural changes induced by activating mutations has been frequently utilized to study activation mechanisms of G-protein-coupled…”
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Influenza A virus protein PB1-F2 from different strains shows distinct structural signatures by Solbak, Sara M.Ø., Sharma, Alok, Bruns, Karsten, Röder, René, Mitzner, David, Hahn, Friedrich, Niebert, Rebekka, Vedeler, Anni, Henklein, Petra, Henklein, Peter, Schubert, Ulrich, Wray, Victor, Fossen, Torgils

“…The proapoptotic influenza A virus PB1-F2 protein contributes to viral pathogenicity and is present in most human and avian influenza isolates. The structures…”
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Structural characterization of the HIV-1 Vpr N terminus: evidence of cis/trans-proline isomerism by Bruns, Karsten, Fossen, Torgils, Wray, Victor, Henklein, Peter, Tessmer, Uwe, Schubert, Ulrich

“…The 96-residue human immunodeficiency virus (HIV) accessory protein Vpr serves manifold functions in the retroviral life cycle including augmentation of viral…”
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Tryparedoxin Peroxidase of Leishmania donovani: Molecular Cloning, Heterologous Expression, Specificity, and Catalytic Mechanism by Flohé, Leopold, Budde, Heike, Bruns, Karsten, Castro, Helena, Clos, Joachim, Hofmann, Birgit, Kansal-Kalavar, Sonia, Krumme, Dirk, Menge, Ulrich, Plank-Schumacher, Karin, Sztajer, Helena, Wissing, Joseph, Wylegalla, Claudia, Hecht, Hans-Jürgen

“…Tryparedoxin peroxidase (TXNPx) of Trypanosomatidae is the terminal peroxidase of a complex redox cascade that detoxifies hydroperoxides by NADPH (Nogoceke et…”
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Influenza A virus protein PB1-F2: synthesis and characterization of the biologically active full length protein and related peptides by Henklein, Peter, Bruns, Karsten, Nimtz, Manfred, Wray, Victor, Tessmer, Uwe, Schubert, Ulrich

“…Recently the discovery of a novel 87 amino acid influenza A virus (IAV) protein, named PB1‐F2, has been reported that originates from an alternative reading…”
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The intriguing cyclophilin A-HIV-1 Vpr interaction: prolyl cis/trans isomerisation catalysis and specific binding by Solbak, Sara M, Reksten, Tove R, Wray, Victor, Bruns, Karsten, Horvli, Ole, Raae, Arnt J, Henklein, Petra, Henklein, Peter, Röder, Rene, Mitzner, David, Schubert, Ulrich, Fossen, Torgils

“…Cyclophilin A (CypA) represents a potential target for antiretroviral therapy since inhibition of CypA suppresses human immunodeficiency virus type 1 (HIV-1)…”
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Solution structure of the equine infectious anemia virus p9 protein: a rationalization of its different ALIX binding requirements compared to the analogous HIV-p6 protein by Sharma, Alok, Bruns, Karsten, Röder, René, Henklein, Peter, Votteler, Jörg, Wray, Victor, Schubert, Ulrich

“…The equine infection anemia virus (EIAV) p9 Gag protein contains the late (L-) domain required for efficient virus release of nascent virions from the cell…”
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Synthesis of full length PB1-F2 influenza A virus proteins from 'Spanish flu' and 'bird flu' by Röder, René, Bruns, Karsten, Sharma, Alok, Eissmann, André, Hahn, Friedrich, Studtrucker, Nicole, Fossen, Torgils, Wray, Victor, Henklein, Peter, Schubert, Ulrich

“…The proapoptotic influenza A virus PB1‐F2 protein contributes to viral pathogenicity and is present in most human and avian isolates. Previous synthetic…”
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Structures of tryparedoxins revealing interaction with trypanothione by Hofmann, B, Budde, H, Bruns, K, Guerrero, S A, Kalisz, H M, Menge, U, Montemartini, M, Nogoceke, E, Steinert, P, Wissing, J B, Flohé, L, Hecht, H J

“…Tryparedoxins (TXNs) catalyse the reduction of peroxiredoxin-type peroxidases by the bis-glutathionyl derivative of spermidine, trypanothione, and are relevant…”
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Tryparedoxin Peroxidase of Leishmania donovani: Molecular Cloning, Heterologous Expression, Specificity, and Catalytic Mechanism: Volume 397, Number 2 (January 15, 2002), pages 324–335 by Flohé, Leopold, Budde, Heike, Bruns, Karsten, Castro, Helena, Clos, Joachim, Hofmann, Birgit, Kansal-Kalavar, Sonia, Krumme, Dirk, Menge, Ulrich, Plank-Schumacher, Karin, Sztajer, Helena, Wissing, Joseph, Wylegalla, Claudia, Hecht, Hans-Jürgen

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Tryparedoxin Peroxidase of Leishmania donovani: Molecular Cloning, Heterologous Expression, Specificity, and Catalytic Mechanism by Flohé, Leopold, Budde, Heike, Bruns, Karsten, Castro, Helena, Clos, Joachim, Hofmann, Birgit, Kansal-Kalavar, Sonia, Krumme, Dirk, Menge, Ulrich, Plank-Schumacher, Karin, Sztajer, Helena, Wissing, Joseph, Wylegalla, Claudia, Hecht, Hans-Jürgen

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