Search Results - "Bruns, I."

Azacitidine and donor lymphocyte infusions as first salvage therapy for relapse of AML or MDS after allogeneic stem cell transplantation by Schroeder, T, Czibere, A, Platzbecker, U, Bug, G, Uharek, L, Luft, T, Giagounidis, A, Zohren, F, Bruns, I, Wolschke, C, Rieger, K, Fenk, R, Germing, U, Haas, R, Kröger, N, Kobbe, G

“…The combination of azacitidine and donor lymphocyte infusions (DLI) as first salvage therapy for relapse after allogeneic transplantation (allo-HSCT) was…”
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Insufficient stromal support in MDS results from molecular and functional deficits of mesenchymal stromal cells by Geyh, S, Öz, S, Cadeddu, R-P, Fröbel, J, Brückner, B, Kündgen, A, Fenk, R, Bruns, I, Zilkens, C, Hermsen, D, Gattermann, N, Kobbe, G, Germing, U, Lyko, F, Haas, R, Schroeder, T

“…Ineffective hematopoiesis is a major characteristic of myelodysplastic syndromes (MDS) causing relevant morbidity and mortality. Mesenchymal stromal cells…”
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"Activity Matters was great - I now realize: if I move, I'm fitter.": development and process evaluation of a web-based program for persons with multiple sclerosis by Daniel, N, Bruns, I, Casey, B, Coote, S, Daubmann, A, Heesen, C, Riemann-Lorenz, K

“…Research shows that persons with mild to moderate multiple sclerosis are less physically active than healthy controls even though they would benefit from it…”
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5-Azacytidine for the treatment of patients with acute myeloid leukemia or myelodysplastic syndrome who relapse after allo-SCT: a retrospective analysis by Czibere, A, Bruns, I, Kröger, N, Platzbecker, U, Lind, J, Zohren, F, Fenk, R, Germing, U, Schröder, T, Gräf, T, Haas, R, Kobbe, G

“…Patients with AML or myelodysplastic syndrome who relapse after allo-SCT have a poor prognosis. In the search for novel treatment strategies for these…”
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Impact of carbonaceous aerosol emissions on regional climate change by ROECKNER, E, STIER, P, FEICHTER, J, KLOSTER, S, ESCH, M, FISCHER-BRUNS, I

“…The past and future evolution of atmospheric composition and climate has been simulated with a version of the Max Planck Institute Earth System Model…”
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The hematopoietic stem cell in chronic phase CML is characterized by a transcriptional profile resembling normal myeloid progenitor cells and reflecting loss of quiescence by Bruns, I, Czibere, A, Fischer, J C, Roels, F, Cadeddu, R-P, Buest, S, Bruennert, D, Huenerlituerkoglu, A N, Stoecklein, N H, Singh, R, Zerbini, L F, Jäger, M, Kobbe, G, Gattermann, N, Kronenwett, R, Brors, B, Haas, R

“…We found that composition of cell subsets within the CD34+ cell population is markedly altered in chronic phase (CP) chronic myeloid leukemia (CML)…”
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First-in-human study of the monopolar spindle 1 (Mps1) kinase inhibitor BAY 1161909 in combination with paclitaxel in subjects with advanced malignancies by Lorusso, P, Chawla, S P, Bendell, J, Shields, A F, Shapiro, G, Rajagopalan, P, Cyris, C, Bruns, I, Mei, J, Souza, F, Rasco, D, Eder, J P, Tolcher, A W

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Sorafenib (Nexavar® ) induces molecular remission and regression of extramedullary disease in a patient with FLT3-ITD+ acute myeloid leukemia by Safaian, N.N, Czibere, A, Bruns, I, Fenk, R, Reinecke, P, Dienst, A, Haas, R, Kobbe, G

“…Abstract The fms-related tyrosine kinase 3 internal tandem duplication (FLT3-ITD) can be found in about one quarter of patients with acute myeloid leukemia…”
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Molecular signature of CD34 hematopoietic stem and progenitor cells of patients with CML in chronic phase by DIAZ-BLANCO, E, BRUNS, I, BAER, A, ROHR, U.-P, KOBBE, G, VON HAESELER, A, GATTERMANN, N, HAAS, R, KRONENWETT, R, NEUMANN, F, FISCHER, J. C, GRAEF, T, ROSSKOPF, M, BRORS, B, PECHTEL, S, BORK, S, KOCH, A

“…In this study, we provide a molecular signature of highly enriched CD34+ cells from bone marrow of untreated patients with chronic myelogenous leukemia (CML)…”
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PB1820: CD47‐BLOCKER TTI‐622 COMBINED WITH AZACITIDINE IN PATIENTS WITH TP53‐MUTATED ACUTE MYELOID LEUKEMIA (AML) AND WITH AZACITIDINE + VENETOCLAX IN ELDERLY OR UNFIT PATIENTS WITH TP53‐WILDTYPE AML by Daver, N., Maris, M., Ramchandren, R., Bixby, D., Doucette, K., Mawad, R., Egan, D., Stevens, D., Zonder, J., Molloy, N., Scheuber, A., Bruns, I., Mantzaris, I., Konopleva, M., Goldberg, A. D.

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Pegfilgrastim for PBSC mobilization and autologous haematopoietic SCT by Kobbe, G, Bruns, I, Fenk, R, Czibere, A, Haas, R

“…To date, G-CSF is the most favoured cytokine administered for PBSC mobilization because of its great efficacy and lack of serious toxicity. Recently, a…”
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Bendamustine in patients with relapsed or refractory multiple myeloma by Michael, M, Bruns, I, Bölke, E, Zohren, F, Czibere, A, Safaian, N N, Neumann, F, Haas, R, Kobbe, G, Fenk, Roland

“…In patients with multiple myeloma, bendamustine monotherapy is effective as 1st and 2nd line therapy. However, data for patients with advanced multiple myeloma…”
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Early in vivo changes of the transcriptome in Philadelphia chromosome-positive CD34+ cells from patients with chronic myelogenous leukaemia following imatinib therapy by Bruennert, D, Czibere, A, Bruns, I, Kronenwett, R, Gattermann, N, Haas, R, Neumann, F

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Complete remission in a patient with relapsed angioimmunoblastic T-cell lymphoma following treatment with bevacizumab by BRUNS, I, FOX, F, REINECKE, P, KOBBE, G, KRONENWETT, R, JUNG, G, HAAS, R

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A 3-day short course of palifermin before HDT reduces toxicity and need for supportive care after autologous blood stem-cell transplantation in patients with multiple myeloma by Kobbe, G., Bruns, I., Schroeder, T., Czibere, A., Warnecke, J., Hieronimus, N., Safaian, N., Kondakci, M., Saure, C., Germing, U., Haas, R., Fenk, R.

“…We retrospectively determined whether a 3-day short course of palifermin could reduce the toxicity of high-dose therapy (HDT) and autologous blood stem-cell…”
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Tacrolimus and mycofenolate mofetil as GvHD prophylaxis following nonmyeloablative conditioning and unrelated hematopoietic SCT for adult patients with advanced hematologic diseases by Zohren, F, Schroeder, T, Czibere, A, Fenk, R, Bruns, I, Kondakci, M, Saure, C, Haas, R, Kobbe, G

“…In the current study, we evaluated a combination of tacrolimus and mycophenolate mofetil (MMF) as GvHD prophylaxis in 50 patients undergoing truly…”
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Successful transplantation of peripheral blood stem cells mobilized by chemotherapy and a single dose of pegylated G-CSF in patients with multiple myeloma by STEIDL, U, FENK, R, HAAS, R, KOBBE, G, BRUNS, I, NEUMANN, F, KONDAKCI, M, HOYER, B, GRÄF, T, ROHR, U-P, BORK, S, KRONENWETT, R

“…Following induction therapy and 4 g/m(2) cyclophosphamide, a single dose of 12 mg polyethyleneglycol-conjugated G-CSF (pegfilgrastim; n=12) or daily doses of…”
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Fludarabine, amsacrine, high-dose cytarabine and 12Gy total body irradiation followed by allogeneic hematopoietic stem cell transplantation is effective in patients with relapsed or high-risk acute lymphoblastic leukemia by Zohren, F, Czibere, A, Bruns, I, Fenk, R, Schroeder, T, Graef, T, Haas, R, Kobbe, G

“…In this prospective study, we examined the toxicity and efficacy of an intensified conditioning regimen for treatment of patients with relapsed or high-risk…”
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Fludarabine, amsacrine, high-dose cytarabine and 12 Gy total body irradiation followed by allogeneic hematopoietic stem cell transplantation is effective in patients with relapsed or high-risk acute lymphoblastic leukemia by Zohren, F, Czibere, A, Bruns, I, Fenk, R, Schroeder, T, Gräf, T, Haas, R, Kobbe, G

“…In this prospective study, we examined the toxicity and efficacy of an intensified conditioning regimen for treatment of patients with relapsed or high-risk…”
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Splenic rupture following administration of pegfilgrastim in a patient with multiple myeloma undergoing autologous peripheral blood stem cell transplantation by Kuendgen, A, Fenk, R, Bruns, I, Dommach, M, Schutte, A, Engers, R, Hünerlitürkoglu, A, Haas, R, Kobbe, G

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