Search Results - "Bruno A. Rocha"

Pre-clinical evaluation of quinoxaline-derived chalcones in tuberculosis by Muradás, Thaís C, Abbadi, Bruno L, Villela, Anne D, Macchi, Fernanda S, Bergo, Pedro F, de Freitas, Talita F, Sperotto, Nathalia D M, Timmers, Luis F S M, Norberto de Souza, Osmar, Picada, Jaqueline N, Fachini, Jean, da Silva, Juliana Bondan, de Albuquerque, Nayara C P, Habenschus, Maísa D, Carrão, Daniel B, Rocha, Bruno A, Barbosa Junior, Fernando, de Oliveira, Anderson R M, Mascarello, Alessandra, Neuenfeldf, Patrícia, Nunes, Ricardo J, Morbidoni, Héctor R, Campos, Maria M, Basso, Luiz A, Rodrigues-Junior, Valnês S

“…New effective compounds for tuberculosis treatment are needed. This study evaluated the effects of a series of quinoxaline-derived chalcones against…”
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Urinary concentrations of 25 phthalate metabolites in Brazilian children and their association with oxidative DNA damage by Rocha, Bruno A., Asimakopoulos, Alexandros G., Barbosa, Fernando, Kannan, Kurunthachalam

“…Exposure of humans to phthalates has received considerable attention due to the ubiquitous occurrence and potential adverse health effects of these chemicals…”
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Proteomic analysis and purification of an unusual germin-like protein with proteolytic activity in the latex of Thevetia peruviana by de Freitas, Cleverson D. T., da Cruz, Wallace T., Silva, Maria Z. R., Vasconcelos, Ilka M., Moreno, Frederico B. M. B., Moreira, Renato A., Monteiro-Moreira, Ana C. O., Alencar, Luciana M. R., Sousa, Jeanlex S., Rocha, Bruno A. M., Ramos, Márcio V.

“…More than 20,000 plant species produce latex, including Apocynaceae, Sapotaceae, Papaveraceae and Euphorbiaceae. To better understand the physiological role…”
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Purification, Partial Characterization, and CNBr-Sepharose Immobilization of a Vasorelaxant Glucose/Mannose Lectin from Canavalia virosa Seeds by Osterne, Vinicius J. S, Santiago, Mayara Q, Pinto-Junior, Vanir R, Cajazeiras, João B, Correia, Jorge L. A, Leitão, Cintia C. F, Carneiro, Rômulo F, Pereira-Junior, Francisco N, Vasconcelos, Mayron A, Rocha, Bruno A. M, Assreuy, Ana Maria S, Bringel, Pedro Henrique S. F, Nagano, Celso S, Nascimento, Kyria S, Cavada, Benildo S

“…A novel mannose/glucose-binding lectin from Canavalia virosa (designated as ConV) has been purified from seeds of C. virosa by affinity chromatography on a…”
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The Galactose-Binding Lectin Isolated from Vatairea macrocarpa Seeds Enhances the Effect of Antibiotics Against Staphylococcus aureus–Resistant Strain by Santos, Valdenice F., Costa, Maria S., Campina, Fábia F., Rodrigues, Renato R., Santos, Ana L. E., Pereira, Felipe M., Batista, Karla L. R., Silva, Rafael C., Pereira, Raquel O., Rocha, Bruno A. M., Coutinho, Henrique D. M., Teixeira, Claudener S.

“…The use of natural products together with standard antimicrobial drugs has recently received more attention as a strategy to combat infectious diseases caused…”
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A Chitin-binding Protein Purified from Moringa oleifera Seeds Presents Anticandidal Activity by Increasing Cell Membrane Permeability and Reactive Oxygen Species Production by Neto, João X S, Pereira, Mirella L, Oliveira, Jose T A, Rocha-Bezerra, Lady C B, Lopes, Tiago D P, Costa, Helen P S, Sousa, Daniele O B, Rocha, Bruno A M, Grangeiro, Thalles B, Freire, José E C, Monteiro-Moreira, Ana Cristina O, Lobo, Marina D P, Brilhante, Raimunda S N, Vasconcelos, Ilka M

“…species are opportunistic pathogens that infect immunocompromised and/or immunosuppressed patients, particularly in hospital facilities, that besides…”
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Anti-inflammatory and Antinociceptive Activity of Chitin-binding Lectin from Canna Limbata Seeds by Araújo, Theolyta S, Teixeira, Claudener S, Falcão, Maria A. P, Junior, Vanir R. Pinto, Santiago, Mayara Quiroz, Benevides, Raquel G, Delatorre, Plínio, Martins, Jorge L, Alexandre-Moreira, Magna S, Cavada, Benildo S, Campesatto, Eliane A, Rocha, Bruno A. M

“…Lectins are a structurally heterogeneous group of proteins or glycoproteins with at least one noncatalytic domain binding reversibly to a specific mono- or…”
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Advanced data mining approaches in the assessment of urinary concentrations of bisphenols, chlorophenols, parabens and benzophenones in Brazilian children and their association to DNA damage by Rocha, Bruno A., Asimakopoulos, Alexandros G., Honda, Masato, da Costa, Nattane L., Barbosa, Rommel M., Barbosa, Fernando, Kannan, Kurunthachalam

“…Human exposure to endocrine disrupting chemicals (EDCs) has received considerable attention over the last three decades. However, little is known about the…”
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Polycyclic aromatic hydrocarbons (PAHs): Updated aspects of their determination, kinetics in the human body, and toxicity by Barbosa, Fernando, Rocha, Bruno A., Souza, Marília C. O., Bocato, Mariana Z., Azevedo, Lara F., Adeyemi, Joseph A., Santana, Anthony, Campiglia, Andres D.

“…Polycyclic aromatic hydrocarbons (PAHs) are legacy pollutants of considerable public health concern. Polycyclic aromatic hydrocarbons arise from natural and…”
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Mass Spectrometry and X-ray Diffraction Analysis of Two Crystal Types of Dioclea virgata Lectin: An Antinociceptive Protein Candidate to Structure/Function Analysis by Delatorre, Plínio, Rocha, Bruno A. M., Simões, Rafael C., Pereira-Júnior, Francisco N., Silva, Helton C., Bezerra, Eduardo Henrique S., Bezerra, Maria Julia B., Marinho, Emmanuel S., Gadelha, Carlos A. A., Santi-Gadelha, Tatiane, Farias, Daniel L., Assreuy, Ana Maria S., Marques-Domingos, Gabriela F. O., Nagano, Celso S., Cavada, Benildo S.

“…The lectin from seeds of Dioclea virgata (DvirL) was purified in a single step affinity chromatography, sequenced by tandem mass spectrometry and submitted to…”
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Structure of a lectin from Canavalia gladiata seeds: new structural insights for old molecules by Delatorre, Plínio, Rocha, Bruno A M, Souza, Emmanuel P, Oliveira, Taianá M, Bezerra, Gustavo A, Moreno, Frederico B M B, Freitas, Beatriz T, Santi-Gadelha, Tatiane, Sampaio, Alexandre H, Azevedo, Jr, Walter F, Cavada, Benildo S

“…Lectins are mainly described as simple carbohydrate-binding proteins. Previous studies have tried to identify other binding sites, which possible recognize…”
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In vitro antiproliferative effects of Vatairea macrocarpa (Benth.) Ducke lectin on human tumor cell lines and in vivo evaluation of its toxicity in Drosophila melanogaster by Costa, Adrielle R., Santos, Antonio M.O., Barreto, Francisco S., Costa, Pedro M.S., Roma, Renato R., Rocha, Bruno A.M., Oliveira, Carlos V.B., Duarte, Antonia E., Pessoa, Claudia, Teixeira, Claudener S.

“…Tumor cells may develop alterations in glycosylation patterns during the initial phase of carcinogenesis. These alterations may be important therapeutic…”
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Occurrence of trace elements in print paper products: Non-carcinogenic risk assessment through dermal exposure by Adeyemi, Joseph A., Cruz, Jonas C., Ayo-Awe, Tolulope V., Rocha, Bruno A., Adedire, Chris O., de Oliveira-Souza, Vanessa C., Oliveira Souza, Marília Cristina, Domingo, José L., Barbosa, Fernando

“…Over time, the risk assessment of dermal exposure to pollutants in print paper products has received considerable attention. Most studies have focused on…”
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Purification, Characterization, and Preliminary X-Ray Diffraction Analysis of a Lactose-Specific Lectin from Cymbosema roseum Seeds by Rocha, Bruno A. M, Moreno, Frederico B. M. B, Delatorre, Plínio, Souza, Emmanuel P, Marinho, Emmanuel S, Benevides, Raquel G, Rustiguel, Joane Kathelen Rodrigues, Souza, Luis A. G, Nagano, Celso S, Debray, Henri, Sampaio, Alexandre H, de Azevedo, Walter F. Jr, Cavada, Benildo S

“…The unique carbohydrate-binding property of lectins makes them invaluable tools in biomedical research. Here, we report the purification, partial primary…”
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Purification and partial characterization of a new mannose/glucose-specific lectin from Dialium guineense Willd seeds that exhibits toxic effect by Bari, Alfa U., Silva, Helton C., Silva, Mayara T. L., Pereira Júnior, Francisco N., Cajazeiras, João B., Sampaio, Alexandre H., Leal, Rodrigo B., Teixeira, Edson H., Rocha, Bruno A. M., Nascimento, Kyria S., Nagano, Celso S., Cavada, Benildo S.

“…A new mannose/glucose‐specific lectin, named DigL, was purified from seeds of Dialium guineense by a single step using a Sepharose 4b‐Mannose affinity…”
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DVL, lectin from Dioclea violacea seeds, has multiples mechanisms of action against Candida spp via carbohydrate recognition domain by Silva, Romério R.S., Malveira, Ellen A., Aguiar, Tawanny K.B., Neto, Nilton A.S., Roma, Renato R., Santos, Maria H.C., Santos, Ana L.E., Silva, Ayrles F.B., Freitas, Cleverson D.T., Rocha, Bruno A.M., Souza, Pedro F.N., Teixeira, Claudener S.

“…Lectins are proteins of non-immunological origin with the ability to bind to carbohydrates reversibly. They emerge as an alternative to conventional…”
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Dioclea violacea lectin increases the effect of neomycin against multidrug-resistant strains and promotes the purification of the antibiotic in immobilized lectin column by Santos, Maria H.C., Santos, Valdenice F., Freitas, Priscilla R., Silva, Romério R.S., Roma, Renato Rodrigues, Santos, Ana L.E., Ribeiro, Daiany Alves, Coutinho, Henrique D.M., Rocha, Bruno A.M., Oliveira, Manoel M.E., Teixeira, Claudener S.

“…DVL is a Man/Glc-binding lectin from Dioclea violacea seeds that has the ability to interact with the antibiotic gentamicin. The present work aimed to evaluate…”
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Purification, Characterization and Evaluation of the Anticoagulant Effect of an Uncompetitive Trypsin Inhibitor obtained from Bauhinia pulchella (Benth) Seeds by Roma, Renato R, Dias, Lucas P, Santos, Ana L E, Silva, Romério R S, Santos, Maria H C, Rocha, Bruno A M, Carneiro, Rômulo F, Nagano, Celso S, Sampaio, Alexandre H, Oliva, Maria L V, Silva, Cláudio G L, Souza, Racquel O S, Teixeira, Claudener S

“…Trypsin inhibitors (TIs) have the ability to competitively or non-competitively bind to trypsin and inhibit its action. These inhibitors are commonly found in…”
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Machaerium acutifolium lectin alters membrane structure and induces ROS production in Candida parapsilosis by Dias, Lucas P., Santos, Ana L.E., Araújo, Nadine M.S., Silva, Romério R.S., Santos, Maria H.C., Roma, Renato R., Rocha, Bruno A.M., Oliveira, Jose T.A., Teixeira, Claudener S.

“…Lectins are a group of widely distributed and structurally heterogeneous proteins of nonimmune origin. These proteins have the ability to interact with glycans…”
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Parkia platycephala lectin enhances the antibiotic activity against multi-resistant bacterial strains and inhibits the development of Haemonchus contortus by Silva, Romerio R.S., Silva, Carolina R., Santos, Valdenice F., Barbosa, Cristina R.S., Muniz, Debora F., Santos, Ana L.E., Santos, Maria H.C., Rocha, Bruno A.M., Batista, Karla L.R., Costa-Júnior, Livio M., Coutinho, Henrique D.M., Teixeira, Claudener S.

“…Lectins have been studied in the past few years as an alternative to inhibit the development of pathogenic bacteria and gastrointestinal nematodes of small…”
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