Search Results - "Bruno, M."
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Mesenchymal stem cell perspective: cell biology to clinical progress
Published in npj Regenerative medicine (02-12-2019)“…The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell population of multipotential stem/progenitor cells commonly referred to…”
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A divalent siRNA chemical scaffold for potent and sustained modulation of gene expression throughout the central nervous system
Published in Nature biotechnology (01-08-2019)“…Sustained silencing of gene expression throughout the brain using small interfering RNAs (siRNAs) has not been achieved. Here we describe an siRNA…”
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3
Photoredox C(2)-Arylation of Indole- and Tryptophan-Containing Biomolecules
Published in Organic letters (17-05-2024)“…We introduce a novel and straightforward methodology for photoredox arylation of an indole scaffold using aryldiazonium salts under mild and metal-free…”
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Parameters influencing the size of chitosan-TPP nano- and microparticles
Published in Scientific reports (16-03-2018)“…Chitosan nanoparticles, produced by ionic gelation, are among the most intensely studied nanosystems for drug delivery. However, a lack of inter-laboratory…”
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5
Abdominal compartment syndrome and intra-abdominal hypertension
Published in Current opinion in critical care (01-12-2019)“…Abdominal compartment syndrome (ACS) is a severe complication resulting from an acute and sustained increase in intra-abdominal pressure (IAP), causing…”
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6
Variations on the Maiani-Testa approach and the inverse problem
Published in The journal of high energy physics (01-06-2021)“…A bstract We discuss a method to construct hadronic scattering and decay amplitudes from Euclidean correlators, by combining the approach of a regulated…”
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Targeting CXCR1/2 Significantly Reduces Breast Cancer Stem Cell Activity and Increases the Efficacy of Inhibiting HER2 via HER2-Dependent and -Independent Mechanisms
Published in Clinical cancer research (01-02-2013)“…Breast cancer stem-like cells (CSC) are an important therapeutic target as they are predicted to be responsible for tumor initiation, maintenance, and…”
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Deep Cortical Layers Are Activated Directly by Thalamus
Published in Science (American Association for the Advancement of Science) (28-06-2013)“…The thalamocortical (TC) projection to layer 4 (L4) is thought to be the main route by which sensory organs communicate with cortex. Sensory information is…”
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Ceramide: A simple sphingolipid with unique biophysical properties
Published in Progress in lipid research (01-04-2014)“…Ceramides are involved in a variety of cellular processes and in disease. Their biological functions are thought to depend on ceramides’ unique biophysical…”
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Kinetic Evidence That the Solvent Barrier for Electron Transfer Is Absent in the Electric Double Layer
Published in Journal of the American Chemical Society (02-09-2020)“…Classical capacitance studies have revealed that the first layer of water present at an aqueous metal–electrolyte interface has a dielectric constant less than…”
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11
Deep strong light–matter coupling in plasmonic nanoparticle crystals
Published in Nature (London) (30-07-2020)“…In the regime of deep strong light–matter coupling, the coupling strength exceeds the transition energies of the material 1 – 3 , fundamentally changing its…”
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Life cycle assessment of chitosan production in India and Europe
Published in The international journal of life cycle assessment (01-05-2018)“…Purpose The aim of this article is to present the first life cycle assessment of chitosan production based on data from two real producers located in India and…”
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Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling
Published in Nature communications (01-11-2019)“…Dissemination of tumour cells to the bone marrow is an early event in breast cancer, however cells may lie dormant for many years before bone metastases…”
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Multifunctionalized iron oxide nanoparticles for selective drug delivery to CD44-positive cancer cells
Published in Nanotechnology (12-02-2016)“…Nanomedicine nowadays offers novel solutions in cancer therapy and diagnosis by introducing multimodal treatments and imaging tools in one single formulation…”
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15
Effects and Mechanisms of Wakefulness on Local Cortical Networks
Published in Neuron (Cambridge, Mass.) (24-03-2011)“…Mammalian brains generate internal activity independent of environmental stimuli. Internally generated states may bring about distinct cortical processing…”
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RNAi modulation of placental sFLT1 for the treatment of preeclampsia
Published in Nature biotechnology (01-12-2018)“…Preeclampsia, a hypertension condition with no approved therapies, is treated in monkeys by gene silencing in the placenta. Preeclampsia is a placentally…”
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17
Graph Convolutional Recurrent Neural Networks for Water Demand Forecasting
Published in Water resources research (01-07-2022)“…Short‐term forecasting of water demand is a crucial process for managing efficiently water supply systems. This paper proposes to develop a novel graph…”
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18
Supermassive Black Holes as the Regulators of Star Formation in Central Galaxies
Published in The Astrophysical journal (01-08-2017)“…We present the relationship between the black hole mass, stellar mass, and star formation rate (SFR) of a diverse group of 91 galaxies with dynamically…”
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Towards a theory of coarse geometry of operator spaces
Published in Israel journal of mathematics (01-03-2024)“…We introduce two notions of coarse embeddability between operator spaces: almost complete coarse embeddability of bounded subsets and spherically-complete…”
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Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity
Published in Cell reports (Cambridge) (29-09-2015)“…Breast cancers (BCs) typically express estrogen receptors (ERs) but frequently exhibit de novo or acquired resistance to hormonal therapies. Here, we show that…”
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