Search Results - "Bruno, Ivone G"

Identification of a MicroRNA that Activates Gene Expression by Repressing Nonsense-Mediated RNA Decay by Bruno, Ivone G., Karam, Rachid, Huang, Lulu, Bhardwaj, Anjana, Lou, Chih H., Shum, Eleen Y., Song, Hye-Won, Corbett, Mark A., Gifford, Wesley D., Gecz, Jozef, Pfaff, Samuel L., Wilkinson, Miles F.

“…Nonsense-mediated decay (NMD) degrades both normal and aberrant transcripts harboring stop codons in particular contexts. Mutations that perturb NMD cause…”
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Transient introduction of human telomerase mRNA improves hallmarks of progeria cells by Li, Yanhui, Zhou, Gang, Bruno, Ivone G., Zhang, Ning, Sho, Sei, Tedone, Enzo, Lai, Tsung‐Po, Cooke, John P., Shay, Jerry W.

“…Hutchinson–Gilford progeria syndrome (HGPS) is characterized by accelerated senescence due to a de novo mutation in the LMNA gene. The mutation produces an…”
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Telomerase mRNA Reverses Senescence in Progeria Cells by Li, Yanhui, Zhou, Gang, Bruno, Ivone G., Cooke, John P.

“…The present study was driven by the hypothesis that transient expression of human telomerase might restore telomere length sufficiently to reverse the…”
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High yield recovery of equine mesenchymal stem cells from umbilical cord matrix/Wharton's jelly using a semi-automated process by Nazari-Shafti, Timo Z, Bruno, Ivone G, Martinez, Rudy F, Coleman, Michael E, Alt, Eckhard U, McClure, Scott R

“…Umbilical cord is an abundant source of perinatal, plastic adherent mesenchymal stem cells (UC-MSCs). UC-MSCs exhibit robust stemness and strong…”
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Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements by Bruno, Ivone G., Jin, Wei, Cote, Gilbert J.

“…Alternative RNA splicing is now known to be pervasive throughout the genome and a target of human disease. We evaluated if targeting intronic splicing…”
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Polypyrimidine tract-binding protein down-regulates fibroblast growth factor receptor 1 α-exon inclusion by WEI JIN, BRUNO, Ivone G, XIE, Tong-Xin, SANGER, Laura J, COTE, Gilbert J

“…Exclusion of the alpha-exon by alternative RNA splicing of the fibroblast growth factor receptor 1 (FGFR1) primary transcript leads to the production of…”
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Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements by Bruno, Ivone G., Jin, Wei, Cote, Gilbert J.

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A MicroRNA Upregulates Neuron‐Specific Transcripts through the NMD Pathway by Wilkinson, Miles Frome, Huang, Lulu, Bhalla, Angela D, Bhardwaj, Anjana, Song, Hye‐Won, Karam, Rachid, Bruno, Ivone G

“…Cells are equipped with multiple RNA regulatory mechanisms that control the expression of specific proteins. Here we report that an miRNA expressed selectively…”
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