Search Results - "Brunner–Ferber, Françoise"

Azithromycin to prevent Pseudomonas aeruginosa ventilator-associated pneumonia by inhibition of quorum sensing: a randomized controlled trial by van Delden, Christian, Köhler, Thilo, Brunner-Ferber, Françoise, François, Bruno, Carlet, Jean, Pechère, Jean-Claude

“…Purpose Anti-virulence strategies have not been evaluated for the prevention of bacterial infections. Prolonged colonization of intubated patients with…”
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An innovative ethosuximide granule formulation designed for pediatric use: Comparative pharmacokinetics, safety, tolerability, and palatability profile versus reference syrup by Diezi, Léonore, Dao, Kim, Jullien, Vincent, Roussel‐Maupetit, Caroline, Burton, Ingrid, André, Pascal, Bardinet, Carine, Rothuizen, Laura E., Chtioui, Haithem, Manso‐Silvan, Maria A., Guittet, Catherine, Brunner‐Ferber, Françoise, Vandenhende, Francois, Chiron, Catherine, Granier, Luc‐André, Buclin, Thierry

“…Ethosuximide, the first‐line therapy for childhood absence epilepsy, is currently formulated as a syrup (Zarontin®, Pfizer) with a bitter taste and high sugar…”
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Efficacy of THN102 (a combination of modafinil and flecainide) on vigilance and cognition during 40‐hour total sleep deprivation in healthy subjects: Glial connexins as a therapeutic target by Sauvet, Fabien, Erblang, Mégane, Gomez‐Merino, Danielle, Rabat, Arnaud, Guillard, Mathias, Dubourdieu, Dominique, Lefloch, Hervé, Drogou, Catherine, Van Beers, Pascal, Bougard, Clément, Bourrrilhon, Cyprien, Arnal, Pierrick, Rein, Werner, Mouthon, Franck, Brunner‐Ferber, Francoise, Leger, Damien, Dauvilliers, Yves, Chennaoui, Mounir, Charvériat, Mathieu

“…Aims THN102 is a novel combination of modafinil and low‐dose flecainide, targeting glial connexin activity to modulate modafinil effects. We investigated…”
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Effects of a New Selective Estrogen Receptor Modulator (MDL 103,323) on Cancellous and Cortical Bone in Ovariectomized Ewes: A Biochemical, Histomorphometric, and Densitometric Study by Chavassieux, Pascale, Garnero, Patrick, Duboeuf, Francois, Vergnaud, Philippe, Brunner‐Ferber, Francoise, Delmas, Pierre D., Meunier, Pierre J.

“…The aims of this study performed in ewes were: (1) to confirm in this animal model the effects on bone of ovariectomy (OVX) alone or associated with Lentaron…”
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Biases affecting injected doses of an experimental drug during clinical trials by Perrottet, Nancy, Brunner-Ferber, Françoise, Grouzmann, Eric, Spertini, François, Biollaz, Jérôme, Buclin, Thierry, Widmer, Nicolas

“…During clinical trials, researchers rarely question nominal doses specified on labels of investigational products, overlooking the potential for inaccuracies…”
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Trastuzumab versus MYL-1401O (a proposed trastuzumab biosimilar) in a phase I bioequivalence study: In vivo and in vitro immunomodulation by Audran, Régine, Chtioui, Haithem, Thierry, Anne-Christine, Mayor, Carole, Vallotton, Laure, Dao, Kim, Rothuizen, Laura, Maghraoui, Ali, Pennella, Eduardo J., Brunner-Ferber, Françoise, Buclin, Thierry, Spertini, Francois

“…Abstract only 10 Background: Trastuzumab is a humanized monoclonal antibody targeting breast cancer cells overexpressing the HER2-oncoprotein. During a Phase-I…”
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Comparative pharmacokinetics of lovastatin, simvastatin and pravastatin in humans by Pentikainen, P J, Saraheimo, M, Schwartz, J I, Amin, R D, Schwartz, M S, Brunner-Ferber, F, Rogers, J D

“…Twelve healthy male volunteers received single market-image 40-mg oral doses of lovastatin and simvastatin (both lactone prodrugs), or pravastatin (a…”
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Incremental dosage of the new antipsychotic mazapertine induces tolerance to cardiovascular and cognitive effects in healthy men by Kleinbloesem, C H, Jaquet-Müller, F, al-Hamdan, Y, Baldauf, C, Gisclon, L, Wesnes, K, Curtin, C R, Stubbs, R J, Walker, S A, Brunner-Ferber, F

“…Mazapertine is a structurally novel antipsychotic compound with high affinity for D2, D3, 5-HT1a, and alpha 1 receptors. The objectives were to determine…”
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Blocking the bradykinin response: Pharmacodynamics and safety of icatibant, a potent and selective bradykinin B2 receptor antagonist by Zimmermann, Jens, Rosenkranz, Bernd, Brunner-Ferber, Françoise, Knolle, Jochen

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Assessment of systemic effects of different ophthalmic beta-blockers in healthy volunteers by Bauer, K, Brunner-Ferber, F, Distlerath, L M, Lippa, E A, Binkowitz, B, Till, P, Kaik, G

“…Systemic beta-blockade after single doses of ophthalmic beta-blockers (one drop in each eye) was investigated in healthy volunteers in two randomized,…”
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Absence of metabolic effects of the topical carbonic anhydrase inhibitors MK-927 and sezolamide during two-week ocular administration to normal subjects by Buclin, T, Biollaz, J, Lippa, E A, Brunner-Ferber, F, van Melle, G, Munafo, A, Clineschmidt, C, Schelling, J L

“…Potential systemic effects of the racemic carbonic anhydrase inhibitor MK-927 and its S-enantiomer, sezolamide hydrochloride, after topical ocular…”
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Sezolamide: Additivity to timolol twice daily by GUNNING, F, BECHETOILLE, A, GREVE, E, LIPPA, E. A, PFEIFFER, N, GERLING, J, HOLDER, D, CLINESCHMIDT, C, BUNTINX, A, BRUNNER-FERBER, F. L, GREHN, F

“…Sezolamide, a potent topical carbonic anhydrase inhibitor previously known as MK-417, was studied to determine its ocular hypotensive activity in patients with…”
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Efficacy of THN102, a new combination between modafinil and flecainide low-dose, during total sleep deprivation in healthy subjects: A double-blind, randomized, placebo and modafinil controlled study by Sauvet, Fabien, Erblang, Megane, Gomez-Merino, Danielle, Rabat, Arnaud, Guillard, Mathias, Drogou, Catherine, Beers, M. Pascal Van, Mouthon, M. Franck, Bourrilhon, Cyprien, Debellemaniere, Eden, Brunner-Ferber, Francoise, Chennaoui, Mounir, Charvériat, Mathieu

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Local tolerance and activity of MK-927, a novel topical carbonic anhydrase inhibitor by Lippa, E A, von Denffer, H A, Hofmann, H M, Brunner-Ferber, F L

“…A three-dose, randomized, double-masked, parallel, placebo-controlled ocular tolerance study was undertaken in 12 healthy, normal volunteers with the…”
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Multiple-dose efficacy comparison of the two topical carbonic anhydrase inhibitors sezolamide and MK-927 by Bron, A, Lippa, E A, Gunning, F, Bénichou, C, Lesure, P, Sirbat, D, Royer, J, Flament, J, Clineschmidt, C, Panebianco, D

“…The multiple-dose twice-daily efficacy of the topical carbonic anhydrase inhibitor MK-927, a racemic compound, was compared with that of its pharmacologically…”
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Effects of a dual inhibitor of angiotensin converting enzyme and neutral endopeptidase, MDL 100 240, on endocrine and renal functions in healthy volunteers by Rousso, Philippe, Buclin, Thierry, Nussberger, Jürg, Décosterd, Laurent A, La Roche, Salome D, Brunner-Ferber, Françoise, Brunner, Hans R, Biollaz, Jérôme

“…OBJECTIVETo investigate the endocrine and renal effects of the dual inhibitor of angiotensin converting enzyme and neutral endopeptidase, MDL 100 240. DESIGNA…”
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MK-927: a topically effective carbonic anhydrase inhibitor in patients by Bron, A M, Lippa, E A, Hofmann, H M, Feicht, B I, Royer, J G, Brunner-Ferber, F L, Panebianco, D L, Von Denffer, H A

“…The effects on intraocular pressure of the novel topical carbonic anhydrase inhibitor MK-927 were investigated for the first time in patients. Three drops of…”
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Effects of MDL 100,240, a Dual Inhibitor of Angiotensin-Converting Enzyme and Neutral Endopeptidase on the Vasopressor Response to Exogenous Angiotensin I and Angiotensin II Challenges in Healthy Volunteers by Rousso, Philippe, Buclin, Thierry, Nussberger, Jürg, Brunner-Ferber, Françoise, Brunner, Hans R, Biollaz, Jérôme

“…MDL 100,240, a dual inhibitor of angiotensin-converting enzyme (ACE) and neutral endopeptidase (NEP), was administered intravenously to two panels of four…”
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Site of the action of a synthetic atrial natriuretic peptide evaluated in humans by Biollaz, Jérôme, Bidiville, Jacques, Diézi, Jacques, Waeber, Bernard, Nussberger, Jürg, Brunner–Ferber, Françoise, Gomez, Hector J., Brunner, Hans R.

“…Site of the action of a synthetic atrial natriuretic peptide evaluated in humans. The renal site of the natriuretic effect of human, atrial natriuretic peptide…”
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Activities of Human Acidic Fibroblast Growth Factor in an In Vitro Dermal Equivalent Model by Dubertret, Louis, Brunner-Ferber, Françoise, Misiti, John, Thomas, Kenneth A., Dubertret, Marie-Liesse

“…Acidic fibroblast growth factor is a potent mitogen for human dermal fibroblasts in an in vitro three-dimensional collagen matrix, the “dermal equivalent.”…”
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