Search Results - "Brunner, M"

Early immunologic changes during the onset of atopic dermatitis by Brunner, Patrick M.

“…Atopic dermatitis (AD), which is commonly called eczema, is the most common chronic inflammatory skin disease. The pipeline of new targeted treatments is…”
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Interleukin‐17 alters the biology of many cell types involved in the genesis of psoriasis, systemic inflammation and associated comorbidities by Krueger, James G., Brunner, Patrick M.

“…Psoriasis is a chronic, immune‐mediated, systemic inflammatory disease that is defined by a characteristic skin reaction produced when elevated levels of…”
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Novel immune directed therapies in myelodysplastic syndromes and acute myeloid leukemia by Brunner, Andrew M.

“…Therapies that target the immune system are increasingly used across oncology, including in hematologic malignancies such as myelodysplastic syndromes (MDS)…”
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The immunology of atopic dermatitis and its reversibility with broad-spectrum and targeted therapies by Brunner, Patrick M., MD, Guttman-Yassky, Emma, MD, PhD, Leung, Donald Y.M., MD, PhD

“…Atopic dermatitis (AD), the most common chronic inflammatory skin disease, is driven by both terminal keratinocyte differentiation defects and strong type 2…”
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Trends and Drivers of Water Temperature Extremes in Mountain Rivers by Hamel, A., Brunner, M. I.

“…Water temperature extremes can pose serious threats to the aquatic ecosystems of mountain rivers. These rivers are influenced by snow and glaciermelt, which…”
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Immunologic, microbial, and epithelial interactions in atopic dermatitis by Brunner, Patrick M., Leung, Donald Y.M., Guttman-Yassky, Emma

“…To provide an overview of studies contributing to the understanding of immunologic, microbial, and epithelial interactions in atopic dermatitis. PubMed…”
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Early-onset pediatric atopic dermatitis is characterized by TH2/TH17/TH22-centered inflammation and lipid alterations by Brunner, Patrick M., Israel, Ariel, Zhang, Ning, Leonard, Alexandra, Wen, Huei-Chi, Huynh, Thy, Tran, Gary, Lyon, Sarah, Rodriguez, Giselle, Immaneni, Supriya, Wagner, Annette, Zheng, Xiuzhong, Estrada, Yeriel D., Xu, Hui, Krueger, James G., Paller, Amy S., Guttman-Yassky, Emma

“…Although atopic dermatitis (AD) often starts in early childhood, detailed tissue profiling of early-onset AD in children is lacking, hindering therapeutic…”
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Changing Views of the Role of Langerhans Cells by Romani, Nikolaus, Brunner, Patrick M., Stingl, Georg

“…Langerhans cells (LCs) have long been considered to be the major sensitizing cells in the skin by initiating productive immunity in naive resting T cells. This…”
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Early-onset pediatric atopic dermatitis is TH2 but also TH17 polarized in skin by Esaki, Hitokazu, Brunner, Patrick M., Renert-Yuval, Yael, Czarnowicki, Tali, Huynh, Thy, Tran, Gary, Lyon, Sarah, Rodriguez, Giselle, Immaneni, Supriya, Johnson, Donald B., Bauer, Bruce, Fuentes-Duculan, Judilyn, Zheng, Xiuzhong, Peng, Xiangyu, Estrada, Yeriel D., Xu, Hui, de Guzman Strong, Christina, Suárez-Fariñas, Mayte, Krueger, James G., Paller, Amy S., Guttman-Yassky, Emma

“…Atopic dermatitis (AD) affects 15% to 25% of children and 4% to 7% of adults. Paradigm-shifting discoveries about AD have been based on adult biomarkers,…”
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Identification of combinatorial patterns of post-translational modifications on individual histones in the mouse brain by Tweedie-Cullen, Ry Y, Brunner, Andrea M, Grossmann, Jonas, Mohanna, Safa, Sichau, David, Nanni, Paolo, Panse, Christian, Mansuy, Isabelle M

“…Post-translational modifications (PTMs) of proteins are biochemical processes required for cellular functions and signalling that occur in every sub-cellular…”
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The atopic dermatitis blood signature is characterized by increases in inflammatory and cardiovascular risk proteins by Brunner, Patrick M., Suárez-Fariñas, Mayte, He, Helen, Malik, Kunal, Wen, Huei-Chi, Gonzalez, Juana, Chan, Tom Chih-Chieh, Estrada, Yeriel, Zheng, Xiuzhong, Khattri, Saakshi, Dattola, Annunziata, Krueger, James G., Guttman-Yassky, Emma

“…Beyond classic “allergic”/atopic comorbidities, atopic dermatitis (AD) emerges as systemic disease with increased cardiovascular risk. To better define serum…”
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Population genomics of Populus trichocarpa identifies signatures of selection and adaptive trait associations by Evans, Luke M, Slavov, Gancho T, Rodgers-Melnick, Eli, Martin, Joel, Ranjan, Priya, Muchero, Wellington, Brunner, Amy M, Schackwitz, Wendy, Gunter, Lee, Chen, Jin-Gui, Tuskan, Gerald A, DiFazio, Stephen P

“…Stephen DiFazio and colleagues report the genome sequences and population genomic analyses of 544 black cottonwood trees ( Populus trichocarpa ) along the…”
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Mechanical forces couple bone matrix mineralization with inhibition of angiogenesis to limit adolescent bone growth by Dzamukova, Maria, Brunner, Tobias M., Miotla-Zarebska, Jadwiga, Heinrich, Frederik, Brylka, Laura, Mashreghi, Mir-Farzin, Kusumbe, Anjali, Kühn, Ralf, Schinke, Thorsten, Vincent, Tonia L., Löhning, Max

“…Bone growth requires a specialised, highly angiogenic blood vessel subtype, so-called type H vessels, which pave the way for osteoblasts surrounding these…”
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Epigenetic marking of sperm by post-translational modification of histones and protamines by Brunner, Andrea M, Nanni, Paolo, Mansuy, Isabelle M

“…The concept that individual traits can be acquired and transmitted by the germline through epigenetic mechanisms has gained recognition in the past years…”
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Multicenter analysis of outcomes in blastic plasmacytoid dendritic cell neoplasm offers a pretargeted therapy benchmark by Taylor, Justin, Haddadin, Michael, Upadhyay, Vivek A., Grussie, Erwin, Mehta-Shah, Neha, Brunner, Andrew M., Louissaint, Abner, Lovitch, Scott B., Dogan, Ahmet, Fathi, Amir T., Stone, Richard M., Tallman, Martin S., Rampal, Raajit K., Neuberg, Donna S., Stevenson, Kristen E., Horwitz, Steven M., Lane, Andrew A.

“…Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an uncommon hematologic malignancy with poor outcomes. Existing data on the clinical behavior of BPDCN…”
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Differentiating Staphylococcus aureus from Escherichia coli mastitis: S. aureus triggers unbalanced immune-dampening and host cell invasion immediately after udder infection by Günther, Juliane, Petzl, Wolfram, Bauer, Isabel, Ponsuksili, Siriluck, Zerbe, Holm, Schuberth, Hans-Joachim, Brunner, Ronald M., Seyfert, Hans-Martin

“…The etiology determines quality and extent of the immune response after udder infection (mastitis). Infections with Gram negative bacteria (e.g. Escherichia…”
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Genome-wide analysis of Aux/IAA and ARF gene families in Populus trichocarpa by Kalluri, Udaya C, Difazio, Stephen P, Brunner, Amy M, Tuskan, Gerald A

“…Auxin/Indole-3-Acetic Acid (Aux/IAA) and Auxin Response Factor (ARF) transcription factors are key regulators of auxin responses in plants. We identified the…”
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Acute Myeloid Leukemia: A New Era of Therapies, a New Wave of Toxicities? by Brunner, Andrew M

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Long-term performance of adhesively bonded timber-concrete composites by Tannert, T., Endacott, B., Brunner, M., Vallée, T.

“…Timber-concrete-composite (TCC) floors are a successful example of hybrid structural components. TCC are composed of timber and concrete layers connected by a…”
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FLOWERING LOCUS T duplication coordinates reproductive and vegetative growth in perennial poplar by Hsu, Chuan-Yu, Adams, Joshua P, Kim, Hyejin, No, Kyoungok, Ma, Caiping, Strauss, Steven H, Drnevich, Jenny, Vandervelde, Lindsay, Ellis, Jeffrey D, Rice, Brandon M, Wickett, Norman, Gunter, Lee E, Tuskan, Gerald A, Brunner, Amy M, Page, Grier P, Barakat, Abdelali, Carlson, John E, dePamphilis, Claude W, Luthe, Dawn S, Yuceer, Cetin

“…Annual plants grow vegetatively at early developmental stages and then transition to the reproductive stage, followed by senescence in the same year. In…”
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