Search Results - "Brunner, DB"

Blood Pressure-Independent Cardiac Hypertrophy Induced by Locally Activated Renin-Angiotensin System by Mazzolai, Lucia, Nussberger, Jurg, Aubert, Jean-Francois, Brunner, Dorette B, Gabbiani, Giulio, Brunner, Hans R, Pedrazzini, Thierry

“…Cardiac hypertrophy is frequent in chronic hypertension. The renin-angiotensin system, via its effector angiotensin II (Ang II), regulates blood pressure and…”
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Effect of a new angiotensin converting enzyme inhibitor MK 421 and its lysine analogue on the components of the renin system in healthy subjects by Brunner, D.B., Desponds, G., Biollaz, J., Keller, I., Ferber, F., Gavras, H., Brunner, H.R., Schelling, J.L.

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Measurement of Immunoreactive Angiotensin-(1-7) Heptapeptide in Human Blood by Nussberger, Juerg, Brunner, Dorette B, Nyfeler, Juerg A, Linder, Lilly, Brunner, Hans R

“…The renal enzyme renin cleaves from the hepatic alpha(2)-globulin angiotensinogen angiotensin-(1-10) decapeptide [Ang-(1-10)], which is further metabolized to…”
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True Versus Immunoreactive Angiotensin II in Human Plasma by NUSSBERGER, JURG, BRUNNER, DORETTE B, WAEBER, BERNARD, BRUNNER, HANS R

“…To measure specifically angiotensin- (l-8) octapeptide, peptides were extracted from 2 ml of plasma by reversible adsorption to bonded-phase silica. The…”
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Specific measurement of angiotensin metabolites and in vitro generated angiotensin II in plasma by NUSSBERGER, J, BRUNNER, D. B, WAEBER, B, BRUNNER, H. R

“…Combining high-performance liquid chromatography with radioimmunoassay enabled the precise measurement of different angiotensins and their metabolites in…”
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Repeated administration of the converting enzyme inhibitor cilazapril to normal volunteers by Nussberger, J, Fasanella d'Amore, T, Porchet, M, Waeber, B, Brunner, D B, Brunner, H R, Kler, L, Brown, A N, Francis, R J

“…Cilazapril 1.25 and 5.0 mg p.o. q.d. was administered in double-blind fashion to two groups of six normal volunteers on 8 consecutive days. Blood pressure,…”
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Effect of a new angiotensin converting enzyme inhibitor MK 421 and its lysine analogue on the components of the renin system in healthy subjects by Brunner, DB, Desponds, G, Biollaz, J, Keller, I, Ferber, F, Gavras, H, Brunner, HR, Schelling, JL

“…1 MK 421 and its lysine analogue are two new inhibitors of angiotensin converting enzyme. Ten mg of both compounds were each given p.o. to 12 normotensive…”
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Enalapril maleate and a lysine analogue (MK‐521) in normal volunteers; relationship between plasma drug levels and the renin angiotensin system by Biollaz, J, Schelling, JL, Jacot Des Combes, B, Brunner, DB, Desponds, G, Brunner, HR, Ulm, EH, Hichens, M, Gomez, HJ

“…1 Two single doses of 10 mg each of the converting enzyme inhibitor enalapril maleate or MK‐421 and of its lysine analogue (MK‐521) were administered p.o. to…”
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Discrepancy Between Antihypertensive Effect and Angiotensin Converting Enzyme Inhibition by Captopril by WAEBER, BERNARD, BRUNNER, HANS R, BRUNNER, DORETTE B, CURTET, ANNE-LISE, TURINI, GUSTAVE A, GAVRAS, HARALAMBOS

“…SUMMARY Captopril, an inhibitor of angiotensin conTerting enzyme, was administered twice daily to 13 hypertensive patients for a mean period of 9 weeks…”
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Plasma angiotensins under sustained converting enzyme inhibition with enalapril in normal humans by Nussberger, J, Brunner, D B, Waeber, B, Brunner, H R

“…During converting enzyme inhibition, a striking difference is found between plasma immunoreactive angiotensin (ANG) II and ANG-(1-8)octapeptide as specifically…”
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Plasma vasopressin in rats: effect of sodium, angiotensin, and catecholamines by Brunner, D B, Burnier, M, Brunner, H R

“…A radioimmunoassay was set up to measure plasma arginine vasopressin levels (AVP). Characteristics of the assay include a sensitivity to 0.25 pg, high…”
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Blood pressure maintenance in awake dehydrated rats: renin, vasopressin, and sympathetic activity by Burnier, M, Biollaz, J, Brunner, D B, Brunner, H R

“…The role of vasopressin, the renin system, and sympathetic activity in sustaining blood pressure in the dehydrated state was investigated in normotensive…”
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Lack of angiotensin I accumulation after converting enzyme blockade by enalapril or lisinopril in man by Nussberger, J, Brunner, D B, Waeber, B, Biollaz, J, Brunner, H R

“…In nine normal volunteers, a series of five venous blood samples was obtained before and up to 24 h after converting enzyme inhibition by a single oral dose of…”
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Role of the renin-angiotensin system in the regulation of late steps in aldosterone biosynthesis by sodium intake of potassium-deficient rats by Müller, J, Hofstetter, L, Schwendener-Canlas, P, Brunner, D B, Lund, E G

“…The role of the renin-angiotensin system in the adaptation of late steps in aldosterone biosynthesis to sodium intake was studied in potassium-deficient rats…”
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Angiotensin II blockade in normal man: Interaction of renin and sodium in maintaining blood pressure by Posternak, Laurence, Brunner, Hans R., Gavras, Haralambos, Brunner, Dorette B.

“…Angiotensin II blockade in normal man: Interaction of renin and sodium in maintaining blood pressure. Nine normotensive volunteers underwent six days of…”
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Octapeptide-specific and sensitive assay for angiotensin II in plasma by Nussberger, J, Brunner, D B, Waeber, B, Brunner, H R

“…Angiotensin-(1-8)octapeptide (angiotensin II) is the active principle of the renin-angiotensin system. Crossreaction of angiotensin II-antisera with inactive…”
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Stimulation of aldosterone biosynthesis by sodium sequestration: role of angiotensin II by Müller, J, Lund, E G, Hofstetter, L, Brunner, D B, Haldy, P

“…The role of angiotensin II in the stimulation of aldosterone biosynthesis by sodium sequestration in potassium-deficient rats was assessed by experiments…”
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A potent converting enzyme inhibitor CGS 13928C: drug profile in normal volunteers by SCHALLER, M. D, BRUNNER, D. B, NUSSBERGER, J, TURINI, G. A, SEN, S. B, CHEN, D, WAEBER, B, BRUNNER, H. R

“…The converting enzyme inhibitor CGS 13928C was evaluated in 15 healthy male volunteers. First the efficacy of a single oral dose of 0.5, 1, 2 or 5 mg in…”
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Thyroid hormone-aldosterone interaction on Na+ transport in toad bladder by Rossier, B C, Gäggeler, H P, Brunner, D B, Keller, I, Rossier, M

“…Repeated administration of thyroxine (T4) in vivo (2 microgram/100 g body wt for 6 days) lowered by 2.3 times (P less than 0.025, df = 18) the basal rate of…”
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Measurement of low angiotensin concentrations after ethanol and Dowex extraction procedures by Nussberger, J, Brunner, D B, Waeber, B, Brunner, H R

“…Current radioimmunoassays do not demonstrate total absence of angiotensin II during converting enzyme inhibition. To assess the meaning of plasma angiotensin…”
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