Search Results - "Brunner, Andrea M"
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Identification of combinatorial patterns of post-translational modifications on individual histones in the mouse brain
Published in PloS one (31-05-2012)“…Post-translational modifications (PTMs) of proteins are biochemical processes required for cellular functions and signalling that occur in every sub-cellular…”
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2
Epigenetic marking of sperm by post-translational modification of histones and protamines
Published in Epigenetics & chromatin (20-01-2014)“…The concept that individual traits can be acquired and transmitted by the germline through epigenetic mechanisms has gained recognition in the past years…”
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3
Protocol for the production of micro- and nanoplastic test materials
Published in Microplastics and nanoplastics (05-05-2023)“…Micro- and nanoplastics (MNP) are ubiquitous, but little is known about the risks they pose to human health. Currently available data are of limited use for…”
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Online Prioritization of Toxic Compounds in Water Samples through Intelligent HRMS Data Acquisition
Published in Analytical chemistry (Washington) (30-03-2021)“…LC-HRMS-based nontarget screening (NTS) has become the method of choice to monitor organic micropollutants (OMPs) in drinking water and its sources. OMPs are…”
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Deciphering the Interplay among Multisite Phosphorylation, Interaction Dynamics, and Conformational Transitions in a Tripartite Protein System
Published in ACS central science (27-07-2016)“…Multisite phosphorylation is a common pathway to regulate protein function, activity, and interaction pattern in vivo, but routine biochemical analysis is…”
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Potential of Environmental Enrichment to Prevent Transgenerational Effects of Paternal Trauma
Published in Neuropsychopharmacology (New York, N.Y.) (01-10-2016)“…Adverse experiences in early life are risk factors for the development of behavioral and physiological symptoms that can lead to psychiatric and cognitive…”
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Risk-based prioritization of suspects detected in riverine water using complementary chromatographic techniques
Published in Water research (Oxford) (01-10-2021)“…•Development of comprehensive risk-based prioritization workflow.•Use of complementary chromatographic separations to broaden chemical space covered.•In-vitro…”
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Identification of organic micro-pollutants in surface water using MS-based infrared ion spectroscopy
Published in Chemosphere (Oxford) (01-11-2023)“…Comprehensive monitoring of organic micro-pollutants (OMPs) in drinking water sources relies on non-target screening (NTS) using liquid-chromatography and…”
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Integration of target analyses, non-target screening and effect-based monitoring to assess OMP related water quality changes in drinking water treatment
Published in The Science of the total environment (25-02-2020)“…The ever-increasing production and use of chemicals lead to the occurrence of organic micro-pollutants (OMPs) in drinking water sources, and consequently the…”
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Organic micropollutant removal in full-scale rapid sand filters used for drinking water treatment in The Netherlands and Belgium
Published in Chemosphere (Oxford) (01-12-2020)“…Biological treatment processes have the potential to remove organic micropollutants (OMPs) during water treatment. The OMP removal capacity of conventional…”
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Prioritizing anthropogenic chemicals in drinking water and sources through combined use of mass spectrometry and ToxCast toxicity data
Published in Journal of hazardous materials (15-02-2019)“…[Display omitted] •Visualization of ToxCast data availability and density, including water relevant mechanisms of toxicity.•Efficient prioritization strategy…”
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Effects of high pressure and temperature conditions on the chemical fate of flowback water related chemicals
Published in The Science of the total environment (25-08-2023)“…Environmental risk assessment is generally based on atmospheric conditions for the modelling of chemical fate after entering the environment. However, during…”
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Liquid Chromatography–High-Resolution Mass Spectrometry-Based Target and Nontarget Screening Methods to Characterize Film-Forming Amine-Treated Steam-Water Systems
Published in Industrial & engineering chemistry research (23-12-2020)“…Film-forming amine products (FFAP) are frequently used as corrosion inhibitors in steam-water systems. To have a better understanding of their behavior in the…”
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14
Benchmarking Multiple Fragmentation Methods on an Orbitrap Fusion for Top-down Phospho-Proteoform Characterization
Published in Analytical chemistry (Washington) (21-04-2015)“…Top-down analysis of intact proteins by mass spectrometry provides an ideal platform for comprehensive proteoform characterization, in particular, for the…”
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HERMES: a molecular-formula-oriented method to target the metabolome
Published in Nature methods (01-11-2021)“…Comprehensive metabolome analyses are essential for biomedical, environmental, and biotechnological research. However, current MS1- and MS2-based acquisition…”
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Suspension of micro- and nanoplastic test materials: Liquid compatibility, (bio)surfactants, toxicity and environmental relevance
Published in Environmental pollution (1987) (01-09-2024)“…Micro- and nanoplastics have been detected in environmental compartments from the highest mountains to the deepest seas. They have been shown to be present at…”
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NORMAN guidance on suspect and non-target screening in environmental monitoring
Published in Environmental sciences Europe (04-09-2023)“…Increasing production and use of chemicals and awareness of their impact on ecosystems and humans has led to large interest for broadening the knowledge on the…”
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Comparing conventional and green fracturing fluids by chemical characterisation and effect-based screening
Published in The Science of the total environment (10-11-2021)“…There is public and scientific concern about air, soil and water contamination and possible adverse environmental and human health effects as a result of…”
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Quantifying Positional Isomers (QPI) by Top-Down Mass Spectrometry
Published in Molecular & cellular proteomics (01-01-2021)“…Proteomics has exposed a plethora of posttranslational modifications, but demonstrating functional relevance requires new approaches. Top-down proteomics of…”
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Clustering and prioritization to design a risk-based monitoring program in groundwater sources for drinking water
Published in Environmental sciences Europe (01-12-2021)“…Background The number of chemical parameters included in monitoring programs of water utilities increased in the last decade. In accordance with the European…”
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